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Diagnostic Markers Significance
Anti-HDV IgG antibody
  • Positive in persons exposed to HDV
  • Persists, even after viral clearance
Anti-HDV IgM antibody
  • Positive in acute infection
  • Negative in past infection
  • Persists in many patients with chronic infection
HDV RNA

Qualitative - Positive in chronic infection

Negative in spontaneous or treatment-induced viral clearance

Quantitative - Useful in monitoring or predicting treatment response

HBxAg
HBV DNA
HBV DNA Polymerase
HBV DNA Polymerase