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:*Useful in monitoring or predicting treatment response
:*Useful in monitoring or predicting treatment response
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| style="padding: 5px 5px; background: #DCDCDC;" | '''HBV DNA'''
| style="padding: 5px 5px; background: #DCDCDC;" | '''HBeAg'''
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*Negative in an estimated 85% of patients
*Associated with detectable anti-HBe
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| style="padding: 5px 5px; background: #DCDCDC;" | '''HBV DNA Polymerase'''
| style="padding: 5px 5px; background: #DCDCDC;" | '''HBV DNA Polymerase'''

Revision as of 20:58, 6 August 2014

Diagnostic Markers Significance
Anti-HDV IgG antibody
  • Positive in persons exposed to HDV
  • Persists, even after viral clearance
Anti-HDV IgM antibody
  • Positive in acute infection
  • Negative in past infection
  • Persists in many patients with chronic infection
HDV RNA

Qualitative

  • Marker of HDV replication
  • Positive in chronic infection
  • Negative in spontaneous or treatment-induced viral clearance

Quantitative

  • Useful in monitoring or predicting treatment response
HBsAg

Qualitative

  • Must be positive for HDV infectivity

Quantitative

  • Positively correlated with HDV RNA
  • Falling titer signals HBsAg loss, and hence HDV clearance
  • Useful in monitoring or predicting treatment response
HBeAg
  • Negative in an estimated 85% of patients
  • Associated with detectable anti-HBe
HBV DNA Polymerase
HBV DNA Polymerase