Sandbox: wdx causes: Difference between revisions
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! rowspan="6" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hematologic | ! rowspan="6" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hematologic | ||
|Hereditary neutrophilia | ! align="center" style="background:#DCDCDC;" |Hereditary neutrophilia | ||
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|- | |- | ||
|Chronic idiopathic neutrophilia | ! align="center" style="background:#DCDCDC;" |Chronic idiopathic neutrophilia | ||
| align="center" style="background:#F5F5F5;" + | | |||
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|- | |- | ||
|CML | ! align="center" style="background:#DCDCDC;" |CML | ||
| align="center" style="background:#F5F5F5;" + | | |||
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|- | |- | ||
|Polycythemia Vera | ! align="center" style="background:#DCDCDC;" |Polycythemia Vera | ||
| align="center" style="background:#F5F5F5;" + | | |||
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|- | |- | ||
|Hemolytic anemia | ! align="center" style="background:#DCDCDC;" |Hemolytic anemia | ||
| align="center" style="background:#F5F5F5;" + | | |||
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|- | |- | ||
|Immature thrombocytopenia | ! align="center" style="background:#DCDCDC;" |Immature thrombocytopenia | ||
| align="center" style="background:#F5F5F5;" + | | |||
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|- | |- | ||
! rowspan="6" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Immunology/ | ! rowspan="6" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Immunology/ | ||
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! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings | ||
|- | |- | ||
|RA | ! align="center" style="background:#DCDCDC;" |RA | ||
| align="center" style="background:#F5F5F5;" + | | |||
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| align="center" style="background:#F5F5F5;" + | | |||
| align="center" style="background:#F5F5F5;" + | | |||
|- | |- | ||
!JRA | ! align="center" style="background:#DCDCDC;" |JRA | ||
| align="center" style="background:#F5F5F5;" + | | |||
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|- | |- | ||
!IBD | ! align="center" style="background:#DCDCDC;" |IBD | ||
| align="center" style="background:#F5F5F5;" + | | |||
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|- | |- | ||
|Chronic hepatitis | ! align="center" style="background:#DCDCDC;" |Chronic hepatitis | ||
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|- | |- | ||
|Acute Gout | ! align="center" style="background:#DCDCDC;" |Acute Gout | ||
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|- | |- | ||
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Metabolic | ! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Metabolic | ||
|Diabetic coma | ! align="center" style="background:#DCDCDC;" |Diabetic coma | ||
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|- | |- | ||
|Acidosis | ! align="center" style="background:#DCDCDC;" |Acidosis | ||
| align="center" style="background:#F5F5F5;" + | | |||
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Revision as of 17:20, 13 September 2018
Differentiating Leukocytosis from Other Diseases
- There are no other mimickers of pancytopenia, as the diagnosis can be unequivocally established by laboratory testing (complete blood count).
| Category | Condition | Etiology | Mechanism | Congenital | Acquried | Clinical manifestations | Para−clinical findings | Gold standard | Associated findings | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Demography | History | Symptoms | Signs | |||||||||||||||||||||||
| Lab Findings | ||||||||||||||||||||||||||
| Appearance | Fever | Bleeding | BP | Splenomegaly | Jaundice | Other | CBC | PBS | Bone marrow exam | PT | PTT | UA | ||||||||||||||
| Physiologic | Primary | Secondary | Plt | HB | WBC | |||||||||||||||||||||
| Hematologic | Hereditary neutrophilia | |||||||||||||||||||||||||
| Chronic idiopathic neutrophilia | ||||||||||||||||||||||||||
| CML | ||||||||||||||||||||||||||
| Polycythemia Vera | ||||||||||||||||||||||||||
| Hemolytic anemia | ||||||||||||||||||||||||||
| Immature thrombocytopenia | ||||||||||||||||||||||||||
| Immunology/
Rheumatology |
Condition | Etiology | Bone marrow infiltration | Bone marrow failure | Destruction/
sequestration/ redistribution |
Congenital | Acquried | Demography | History | Appearance | Fever | Bleeding | BP | Splenomegaly | Jaundice | Other signs | Plt | HB | WBC | PBS | Bone marrow exam | PT | PTT | UA | Gold standard | Associated findings |
| RA | ||||||||||||||||||||||||||
| JRA | ||||||||||||||||||||||||||
| IBD | ||||||||||||||||||||||||||
| Chronic hepatitis | ||||||||||||||||||||||||||
| Acute Gout | ||||||||||||||||||||||||||
| Metabolic | Diabetic coma | |||||||||||||||||||||||||
| Acidosis | ||||||||||||||||||||||||||
| Thyroid strom | ||||||||||||||||||||||||||
| Seizures | ||||||||||||||||||||||||||
| Infections | Condition | Etiology | Bone marrow infiltration | Bone marrow failure | Destruction/
sequestration/ redistribution |
Congenital | Acquried | Demography | History | Appearance | Fever | Bleeding | BP | Splenomegaly | Jaundice | Other signs | Plt | HB | WBC | PBS | Bone marrow exam | PT | PTT | UA | Gold standard | Associated findings |
| Acute | ||||||||||||||||||||||||||
| Chronic | ||||||||||||||||||||||||||
| Medications | Steriod | |||||||||||||||||||||||||
| Lithium | ||||||||||||||||||||||||||
| Beta agonists | ||||||||||||||||||||||||||
| Cytokines | ||||||||||||||||||||||||||
| Other | Post splenectomy | |||||||||||||||||||||||||
| Down syndrome | ||||||||||||||||||||||||||
| Birth | ||||||||||||||||||||||||||
| Pregnancy | ||||||||||||||||||||||||||
| Category | Condition | Etiology | Bone marrow infiltration | Bone marrow failure | Destruction/
sequestration/ redistribution |
Congenital | Acquried | Demography | History | Appearance | Fever | Bleeding | BP | Splenomegaly | Jaundice | Other signs | Plt | HB | WBC | PBS | Bone marrow exam | PT | PTT | UA | Gold standard | Associated findings |
- Leukocytosis is defined as an elevated white blood cell (WBC) count greater than 11,000 per mm3 (11.0 × 109 per L).
- The most common type of leukocytosis is neutrophilia.
- Neutrophilia can be defined as an increase in the absolute number of mature neutrophils to greater than 7,000 per mm3 [7.0 × 109 per L].