Sandbox:Mitra3

All patients with acute inferior wall myocardial infarction (ST elevation in leads II, III, aVF)

Obtain right-sided precordial leads

>= 1mm ST elevation in lead V4R

Highly suggestive of RVMI

Physical examination

Echocardiography

Coronary Angiography

Hemodynamic study

❑ Classic triad of: • Hypotension • Elevated JVP • Clear Lungs ❑ Kussmaul sign ❑ Pulsus paradoxus ❑ Tricuspid regurgitation murmur ❑ Atrioventrcicular dissociation ❑ Vagal symptoms: • Bradycardia • Nausea • Vomiting • Diaphoresis • Pallor

❑ RV dilatation ❑ Depressed RV systolic function ❑ RV wall akinesia or dyskinesia ❑ RA enlargement ❑ Elevated pulmonary pressures ❑ Pulmonary regurgitation ❑ Tricuspid regurgitation ❑ Increased right atrial pressure

Gold standard diagnostic modality ❑ In the majority of RVMI: • The culprit artery: Proximal RCA ❑ Occasionally: • The culprit artery: Left circumflex or left anterior descending artery

❑ Hemodynamically significant RVMI: • Increased RAP>10 mmHg • RAP to PCWP ratio >0.8 (normal<0.6) • RAP within 5 mmHg of the PCWP • Reduced cardiac index • Disproportionate elevation of right-sided filling pressures: Hallmark of RVMI ❑ In concomitant LV dysfunction: • RAP to PCWP ratio can change ❑ Additional hemodynamic changes: •Prominent Y-descend of the RAP •Drop of the systemic arterial pressure >10 mmHg with inspiration • "Dip and plateau" morphology and equalization of the diastolic filling pressures