Sandbox:Leptospirosis: Difference between revisions
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Association of renal failure with icteric leptospirosis, was first reported over 100 years ago and described by Adolf Weil. | Association of renal failure with icteric leptospirosis, was first reported over 100 years ago and described by Adolf Weil. | ||
==Pathophysiology== | ==Pathophysiology== | ||
The disease leptospirosis involves a spectrum of symptoms ranging from subclinical infection to a severe syndrome of multiorgan infection with high mortality. | The disease leptospirosis involves a spectrum of symptoms ranging from subclinical infection to a severe syndrome of multiorgan infection with high mortality and Weil’s disease represents only the most severe presentation. Severe leptospirosis is frequently caused by serovars of the icterohaemorrhagiae serogroup. The presentation of leptospirosis is biphasic, with the acute or septicemic phase lasting about a week, followed by the immune phase, characterized by antibody production and excretion of leptospires in the urine.<ref name="Levett2001">{{cite journal|last1=Levett|first1=P. N.|title=Leptospirosis|journal=Clinical Microbiology Reviews|volume=14|issue=2|year=2001|pages=296–326|issn=0893-8512|doi=10.1128/CMR.14.2.296-326.2001}}</ref> | ||
==Causes== | |||
Severe leptospirosis is frequently caused by serovars of the icterohaemorrhagiae serogroup. | |||
==Daignosis== | |||
===History & Symptoms=== | |||
The clinical presentation of leptospirosis is biphasic, with the acute or septicemic phase lasting about a week, followed by the immune phase, characterized by antibody production and excretion of leptospires in the urine.<ref name="Levett2001">{{cite journal|last1=Levett|first1=P. N.|title=Leptospirosis|journal=Clinical Microbiology Reviews|volume=14|issue=2|year=2001|pages=296–326|issn=0893-8512|doi=10.1128/CMR.14.2.296-326.2001}}</ref> | |||
==References== | ==References== | ||
Revision as of 20:01, 16 February 2017
Overview
Leptospirosis is a zoonotic disorder with ubiquitous distribution, caused by Leptospira species.
Historical Perspective
Association of renal failure with icteric leptospirosis, was first reported over 100 years ago and described by Adolf Weil.
Pathophysiology
The disease leptospirosis involves a spectrum of symptoms ranging from subclinical infection to a severe syndrome of multiorgan infection with high mortality and Weil’s disease represents only the most severe presentation. Severe leptospirosis is frequently caused by serovars of the icterohaemorrhagiae serogroup. The presentation of leptospirosis is biphasic, with the acute or septicemic phase lasting about a week, followed by the immune phase, characterized by antibody production and excretion of leptospires in the urine.[1]
Causes
Severe leptospirosis is frequently caused by serovars of the icterohaemorrhagiae serogroup.
Daignosis
History & Symptoms
The clinical presentation of leptospirosis is biphasic, with the acute or septicemic phase lasting about a week, followed by the immune phase, characterized by antibody production and excretion of leptospires in the urine.[1]