Sandbox:Ali
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ali Akram, M.B.B.S.[2]
Overview
Classification
Immunodeficiency disorders are classified into two types:
- Primary immunodeficiency
- Secondary immunodeficiency
Primary immunodeficiency:
| Primary immunodeficiency disorders | ||||
|---|---|---|---|---|
| Phagocyte cell defects | Decreased number
Functional Defects |
Schwachman-Diamond Syndrome
G6PC3 deficiency Cohen Syndrome Barth Syndrome Glycogen Storage Disease Type 1b Clericuzio Syndrome VPS45 deficiency P14/LAMTOR2 deficiency JAGN1 deficiency 3-methylglutaconic aciduria SMARCD2 deficiency WDR1 deficiency HYOU1 deficiency Elastase deficiency HAX1 deficiency(Kostmann Disease) GFI1 deficiency G-CSF receptor deficiency X-linked neutropenia /mylodysplasia WAS GOF Neutropenia with combined immune deficiency Cystic Fibrosis Papillion-Lefèvre Localized juvenile peridontitis B-Actin Leukocyte adhesion deficiency GATA2 def (MonoMac sd) Specific granule deficiency Pulmonary alveolar proteinosis Chronic Granulomatous Disease Rac 2 def G6PD def Class 1 |
||
| Defects in Intrinsic and Innate immunity | Predisposition to bacterial infections | |||