SOCS7

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Suppressor of cytokine signaling 7
Identifiers
Symbols SOCS7 ; NAP4
External IDs Template:OMIM5 Template:MGI HomoloGene16331
RNA expression pattern
File:PBB GE SOCS7 214015 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Suppressor of cytokine signaling 7, also known as SOCS7, is a human gene.[1]


References

  1. "Entrez Gene: SOCS7 suppressor of cytokine signaling 7".

Further reading

  • Cooney RN (2002). "Suppressors of cytokine signaling (SOCS): inhibitors of the JAK/STAT pathway". Shock. 17 (2): 83–90. PMID 11837794.
  • Kile BT, Schulman BA, Alexander WS; et al. (2002). "The SOCS box: a tale of destruction and degradation". Trends Biochem. Sci. 27 (5): 235–41. PMID 12076535.
  • Wormald S, Hilton DJ (2004). "Inhibitors of cytokine signal transduction". J. Biol. Chem. 279 (2): 821–4. doi:10.1074/jbc.R300030200. PMID 14607831.
  • Fujimoto M, Naka T (2004). "Regulation of cytokine signaling by SOCS family molecules". Trends Immunol. 24 (12): 659–66. PMID 14644140.
  • Matuoka K, Miki H, Takahashi K, Takenawa T (1997). "A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2 domain and nuclear signaling motifs". Biochem. Biophys. Res. Commun. 239 (2): 488–92. doi:10.1006/bbrc.1997.7492. PMID 9344857.
  • Hilton DJ, Richardson RT, Alexander WS; et al. (1998). "Twenty proteins containing a C-terminal SOCS box form five structural classes". Proc. Natl. Acad. Sci. U.S.A. 95 (1): 114–9. PMID 9419338.
  • Dogusan Z, Hooghe-Peters EL, Berus D; et al. (2000). "Expression of SOCS genes in normal and leukemic human leukocytes stimulated by prolactin, growth hormone and cytokines". J. Neuroimmunol. 109 (1): 34–9. PMID 10969179.
  • Krebs DL, Uren RT, Metcalf D; et al. (2002). "SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation". Mol. Cell. Biol. 22 (13): 4567–78. PMID 12052866.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Martens N, Wery M, Wang P; et al. (2004). "The suppressor of cytokine signaling (SOCS)-7 interacts with the actin cytoskeleton through vinexin". Exp. Cell Res. 298 (1): 239–48. doi:10.1016/j.yexcr.2004.04.002. PMID 15242778.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Martens N, Uzan G, Wery M; et al. (2005). "Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear translocation". J. Biol. Chem. 280 (14): 13817–23. doi:10.1074/jbc.M411596200. PMID 15677474.
  • Banks AS, Li J, McKeag L; et al. (2005). "Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans". J. Clin. Invest. 115 (9): 2462–71. doi:10.1172/JCI23853. PMID 16127460.
  • Zody MC, Garber M, Adams DJ; et al. (2006). "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage". Nature. 440 (7087): 1045–9. doi:10.1038/nature04689. PMID 16625196.
  • Kremer BE, Adang LA, Macara IG (2007). "Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7". Cell. 130 (5): 837–50. doi:10.1016/j.cell.2007.06.053. PMID 17803907.

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