SLCO2B1: Difference between revisions

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Latest revision as of 18:42, 3 July 2018

Solute carrier organic anion transporter family member 2B1 also known as organic anion-transporting polypeptide 2B1 (OATP2B1) is a protein that in humans is encoded by the gene SLCO2B1.^[1]

References

↑ "Entrez Gene: SLCO2B1 solute carrier organic anion transporter family, member 2B1".

Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485.
Tamai I, Nezu J, Uchino H, et al. (2000). "Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family". Biochem. Biophys. Res. Commun. 273 (1): 251–60. doi:10.1006/bbrc.2000.2922. PMID 10873595.
St-Pierre MV, Hagenbuch B, Ugele B, et al. (2002). "Characterization of an organic anion-transporting polypeptide (OATP-B) in human placenta". J. Clin. Endocrinol. Metab. 87 (4): 1856–63. doi:10.1210/jc.87.4.1856. PMID 11932330.
Nozawa T, Nakajima M, Tamai I, et al. (2002). "Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis". J. Pharmacol. Exp. Ther. 302 (2): 804–13. doi:10.1124/jpet.302.2.804. PMID 12130747.
Ugele B, St-Pierre MV, Pihusch M, et al. (2003). "Characterization and identification of steroid sulfate transporters of human placenta". Am. J. Physiol. Endocrinol. Metab. 284 (2): E390–8. doi:10.1152/ajpendo.00257.2002. PMID 12409283.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Hänggi E, Grundschober AF, Leuthold S, et al. (2006). "Functional analysis of the extracellular cysteine residues in the human organic anion transporting polypeptide, OATP2B1". Mol. Pharmacol. 70 (3): 806–17. doi:10.1124/mol.105.019547. PMID 16754786.
Grube M, Köck K, Karner S, et al. (2006). "Modification of OATP2B1-mediated transport by steroid hormones". Mol. Pharmacol. 70 (5): 1735–41. doi:10.1124/mol.106.026450. PMID 16908597.

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[entrez-1] "Entrez Gene: SLCO2B1 solute carrier organic anion transporter family, member 2B1".

[1]

@@ Line 1: / Line 1: @@
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+{{Infobox_gene}}
-{{PBB_Controls
+'''Solute carrier organic anion transporter family member 2B1''' also known as '''organic anion-transporting polypeptide 2B1''' (OATP2B1) is a [[protein]] that in humans is encoded by the [[gene]] ''SLCO2B1''.<ref name="entrez">{{cite web | title = Entrez Gene: SLCO2B1 solute carrier organic anion transporter family, member 2B1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11309| accessdate = }}</ref>
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-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Solute carrier organic anion transporter family, member 2B1
- | HGNCid = 10962
- | Symbol = SLCO2B1
- | AltSymbols =; DKFZp686E0517; KIAA0880; OATP-B; OATP2B1; OATPB; SLC21A9
- | OMIM = 604988
- | ECnumber =
- | Homologene = 21419
- | MGIid = 1351872
- | GeneAtlas_image1 = PBB_GE_SLCO2B1_203473_at_tn.png
- | GeneAtlas_image2 = PBB_GE_SLCO2B1_203472_s_at_tn.png
- | GeneAtlas_image3 = PBB_GE_SLCO2B1_211557_x_at_tn.png
- | Function = {{GNF_GO|id=GO:0005215 |text = transporter activity}}
- | Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
- | Process = {{GNF_GO|id=GO:0006811 |text = ion transport}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 11309
-    | Hs_Ensembl = ENSG00000137491
-    | Hs_RefseqProtein = NP_009187
-    | Hs_RefseqmRNA = NM_007256
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 11
-    | Hs_GenLoc_start = 74539809
-    | Hs_GenLoc_end = 74594945
-    | Hs_Uniprot = O94956
-    | Mm_EntrezGene = 101488
-    | Mm_Ensembl = ENSMUSG00000030737
-    | Mm_RefseqmRNA = NM_175316
-    | Mm_RefseqProtein = NP_780525
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 7
-    | Mm_GenLoc_start = 99531887
-    | Mm_GenLoc_end = 99585423
-    | Mm_Uniprot = Q05D10
-  }}
-}}
-'''Solute carrier organic anion transporter family, member 2B1''', also known as '''SLCO2B1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SLCO2B1 solute carrier organic anion transporter family, member 2B1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11309| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
@@ Line 60: / Line 12: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
@@ Line 66: / Line 18: @@
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Nagase T, Ishikawa K, Suyama M, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 6 |pages= 355-64 |year= 1999 |pmid= 10048485 |doi=  }}
+*{{cite journal   |vauthors=Nagase T, Ishikawa K, Suyama M, etal |title=Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 6 |pages= 355–64 |year= 1999 |pmid= 10048485 |doi=10.1093/dnares/5.6.355  }}
-*{{cite journal  | author=Tamai I, Nezu J, Uchino H, ''et al.'' |title=Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family. |journal=Biochem. Biophys. Res. Commun. |volume=273 |issue= 1 |pages= 251-60 |year= 2000 |pmid= 10873595 |doi= 10.1006/bbrc.2000.2922 }}
+*{{cite journal   |vauthors=Tamai I, Nezu J, Uchino H, etal |title=Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family. |journal=Biochem. Biophys. Res. Commun. |volume=273 |issue= 1 |pages= 251–60 |year= 2000 |pmid= 10873595 |doi= 10.1006/bbrc.2000.2922 }}
-*{{cite journal  | author=St-Pierre MV, Hagenbuch B, Ugele B, ''et al.'' |title=Characterization of an organic anion-transporting polypeptide (OATP-B) in human placenta. |journal=J. Clin. Endocrinol. Metab. |volume=87 |issue= 4 |pages= 1856-63 |year= 2002 |pmid= 11932330 |doi=  }}
+*{{cite journal   |vauthors=St-Pierre MV, Hagenbuch B, Ugele B, etal |title=Characterization of an organic anion-transporting polypeptide (OATP-B) in human placenta. |journal=J. Clin. Endocrinol. Metab. |volume=87 |issue= 4 |pages= 1856–63 |year= 2002 |pmid= 11932330 |doi=10.1210/jc.87.4.1856  }}
-*{{cite journal  | author=Nozawa T, Nakajima M, Tamai I, ''et al.'' |title=Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis. |journal=J. Pharmacol. Exp. Ther. |volume=302 |issue= 2 |pages= 804-13 |year= 2002 |pmid= 12130747 |doi=  }}
+*{{cite journal   |vauthors=Nozawa T, Nakajima M, Tamai I, etal |title=Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis. |journal=J. Pharmacol. Exp. Ther. |volume=302 |issue= 2 |pages= 804–13 |year= 2002 |pmid= 12130747 |doi=10.1124/jpet.302.2.804  }}
-*{{cite journal  | author=Ugele B, St-Pierre MV, Pihusch M, ''et al.'' |title=Characterization and identification of steroid sulfate transporters of human placenta. |journal=Am. J. Physiol. Endocrinol. Metab. |volume=284 |issue= 2 |pages= E390-8 |year= 2003 |pmid= 12409283 |doi= 10.1152/ajpendo.00257.2002 }}
+*{{cite journal   |vauthors=Ugele B, St-Pierre MV, Pihusch M, etal |title=Characterization and identification of steroid sulfate transporters of human placenta. |journal=Am. J. Physiol. Endocrinol. Metab. |volume=284 |issue= 2 |pages= E390–8 |year= 2003 |pmid= 12409283 |doi= 10.1152/ajpendo.00257.2002 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Hänggi E, Grundschober AF, Leuthold S, ''et al.'' |title=Functional analysis of the extracellular cysteine residues in the human organic anion transporting polypeptide, OATP2B1. |journal=Mol. Pharmacol. |volume=70 |issue= 3 |pages= 806-17 |year= 2006 |pmid= 16754786 |doi= 10.1124/mol.105.019547 }}
+*{{cite journal   |vauthors=Hänggi E, Grundschober AF, Leuthold S, etal |title=Functional analysis of the extracellular cysteine residues in the human organic anion transporting polypeptide, OATP2B1. |journal=Mol. Pharmacol. |volume=70 |issue= 3 |pages= 806–17 |year= 2006 |pmid= 16754786 |doi= 10.1124/mol.105.019547 }}
-*{{cite journal  | author=Grube M, Köck K, Karner S, ''et al.'' |title=Modification of OATP2B1-mediated transport by steroid hormones. |journal=Mol. Pharmacol. |volume=70 |issue= 5 |pages= 1735-41 |year= 2006 |pmid= 16908597 |doi= 10.1124/mol.106.026450 }}
+*{{cite journal   |vauthors=Grube M, Köck K, Karner S, etal |title=Modification of OATP2B1-mediated transport by steroid hormones. |journal=Mol. Pharmacol. |volume=70 |issue= 5 |pages= 1735–41 |year= 2006 |pmid= 16908597 |doi= 10.1124/mol.106.026450 }}
 }}
 {{refend}}
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 {{Membrane transport proteins}}
 [[Category:Solute carrier family]]
-{{WikiDoc Sources}}
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+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}

SLCO2B1: Difference between revisions

Latest revision as of 18:42, 3 July 2018

See also

References

Further reading

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