SLC6A6
| Solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | SLC6A6 ; MGC10619; MGC131729; TAUT | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 2291 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE SLC6A6 205921 s at tn.png | |||||||||||
| File:PBB GE SLC6A6 205920 at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Solute carrier family 6 (neurotransmitter transporter, taurine), member 6, also known as SLC6A6, is a human gene.[1]
References
Further reading
- Uchida S, Kwon HM, Yamauchi A; et al. (1992). "Molecular cloning of the cDNA for an MDCK cell Na(+)- and Cl(-)-dependent taurine transporter that is regulated by hypertonicity". Proc. Natl. Acad. Sci. U.S.A. 89 (17): 8230–4. PMID 1518851.
- Ramamoorthy S, Leibach FH, Mahesh VB; et al. (1994). "Functional characterization and chromosomal localization of a cloned taurine transporter from human placenta". Biochem. J. 300 ( Pt 3): 893–900. PMID 8010975.
- Jhiang SM, Fithian L, Smanik P; et al. (1993). "Cloning of the human taurine transporter and characterization of taurine uptake in thyroid cells". FEBS Lett. 318 (2): 139–44. PMID 8382624.
- Miyamoto Y, Liou GI, Sprinkle TJ (1996). "Isolation of a cDNA encoding a taurine transporter in the human retinal pigment epithelium". Curr. Eye Res. 15 (3): 345–9. PMID 8654117.
- Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548.
- Mochizuki T, Satsu H, Shimizu M (2002). "Tumor necrosis factor alpha stimulates taurine uptake and transporter gene expression in human intestinal Caco-2 cells". FEBS Lett. 517 (1–3): 92–6. PMID 12062416.
- Han X, Patters AB, Chesney RW (2002). "Transcriptional repression of taurine transporter gene (TauT) by p53 in renal cells". J. Biol. Chem. 277 (42): 39266–73. doi:10.1074/jbc.M205939200. PMID 12163498.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Han X, Chesney RW (2003). "Regulation of taurine transporter gene (TauT) by WT1". FEBS Lett. 540 (1–3): 71–6. PMID 12681485.
- Roos S, Powell TL, Jansson T (2004). "Human placental taurine transporter in uncomplicated and IUGR pregnancies: cellular localization, protein expression, and regulation". Am. J. Physiol. Regul. Integr. Comp. Physiol. 287 (4): R886–93. doi:10.1152/ajpregu.00232.2004. PMID 15166008.
- Satsu H, Manabe M, Shimizu M (2004). "Activation of Ca2+/calmodulin-dependent protein kinase II is involved in hyperosmotic induction of the human taurine transporter". FEBS Lett. 569 (1–3): 123–8. doi:10.1016/j.febslet.2004.05.062. PMID 15225620.
- Mochizuki T, Satsu H, Nakano T, Shimizu M (2005). "Regulation of the human taurine transporter by TNF-alpha and an anti-inflammatory function of taurine in human intestinal Caco-2 cells". Biofactors. 21 (1–4): 141–4. PMID 15630186.
- Mochizuki T, Satsu H, Shimizu M (2005). "Signaling pathways involved in tumor necrosis factor alpha-induced upregulation of the taurine transporter in Caco-2 cells". FEBS Lett. 579 (14): 3069–74. doi:10.1016/j.febslet.2005.04.063. PMID 15907840.
- Nakashima E, Pop-Busui R, Towns R; et al. (2006). "Regulation of the human taurine transporter by oxidative stress in retinal pigment epithelial cells stably transformed to overexpress aldose reductase". Antioxid. Redox Signal. 7 (11–12): 1530–42. doi:10.1089/ars.2005.7.1530. PMID 16356117.
- Iruloh CG, D'Souza SW, Speake PF; et al. (2007). "Taurine transporter in fetal T lymphocytes and platelets: differential expression and functional activity". Am. J. Physiol., Cell Physiol. 292 (1): C332–41. doi:10.1152/ajpcell.00634.2005. PMID 16956961.
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