SLC25A19: Difference between revisions

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Latest revision as of 06:29, 11 September 2017

Mitochondrial thiamine pyrophosphate carrier is a protein that in humans is encoded by the SLC25A19 gene.^[1]^[2]^[3]

References

↑ Iacobazzi V, Ventura M, Fiermonte G, Prezioso G, Rocchi M, Palmieri F (Jul 2001). "Genomic organization and mapping of the gene (SLC25A19) encoding the human mitochondrial deoxynucleotide carrier (DNC)". Cytogenet Cell Genet. 93 (1–2): 40–2. doi:10.1159/000056945. PMID 11474176.
↑ Dolce V, Fiermonte G, Runswick MJ, Palmieri F, Walker JE (Mar 2001). "The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals". Proc Natl Acad Sci U S A. 98 (5): 2284–8. doi:10.1073/pnas.031430998. PMC 30130. PMID 11226231.
↑ "Entrez Gene: SLC25A19 solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Rosenberg MJ, Agarwala R, Bouffard G, et al. (2002). "Mutant deoxynucleotide carrier is associated with congenital microcephaly". Nat. Genet. 32 (1): 175–9. doi:10.1038/ng948. PMID 12185364.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Carrisi C, Antonucci D, et al. (2013). "Transport of platinum bonded nucleotides into proteoliposomes, mediated by Drosophila melanogaster thiamine pyrophosphate carrier protein (DmTpc1)". j.jinorgbio. 130: 1172. doi:10.1016/j.jinorgbio.2013.09.012. PMID 24148759.
Lam W, Chen C, Ruan S, et al. (2005). "Expression of deoxynucleotide carrier is not associated with the mitochondrial DNA depletion caused by anti-HIV dideoxynucleoside analogs and mitochondrial dNTP uptake". Mol. Pharmacol. 67 (2): 408–16. doi:10.1124/mol.104.007120. PMID 15539640.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Lindhurst MJ, Fiermonte G, Song S, et al. (2006). "Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia". Proc. Natl. Acad. Sci. U.S.A. 103 (43): 15927–32. doi:10.1073/pnas.0607661103. PMC 1595310. PMID 17035501.
Iacopetta D, Carrisi C, et al. (2010). "The biochemical properties of the mitochondrial thiamine pyrophosphate carrier from Drosophila melanogaster". FEBS J. 277: 1172. doi:10.1111/j.1742-4658.2009.07550.x. PMID 20121944.

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[pmid11474176-1] Iacobazzi V, Ventura M, Fiermonte G, Prezioso G, Rocchi M, Palmieri F (Jul 2001). "Genomic organization and mapping of the gene (SLC25A19) encoding the human mitochondrial deoxynucleotide carrier (DNC)". Cytogenet Cell Genet. 93 (1–2): 40–2. doi:10.1159/000056945. PMID 11474176.

[pmid11226231-2] Dolce V, Fiermonte G, Runswick MJ, Palmieri F, Walker JE (Mar 2001). "The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals". Proc Natl Acad Sci U S A. 98 (5): 2284–8. doi:10.1073/pnas.031430998. PMC 30130. PMID 11226231.

[entrez-3] "Entrez Gene: SLC25A19 solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19".

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Mitochondrial thiamine pyrophosphate carrier''' is a [[protein]] that in humans is encoded by the ''SLC25A19'' [[gene]].<ref name="pmid11474176">{{cite journal | vauthors = Iacobazzi V, Ventura M, Fiermonte G, Prezioso G, Rocchi M, Palmieri F | title = Genomic organization and mapping of the gene (SLC25A19) encoding the human mitochondrial deoxynucleotide carrier (DNC) | journal = Cytogenet Cell Genet | volume = 93 | issue = 1–2 | pages = 40–2 |date=Jul 2001 | pmid = 11474176 | pmc =  | doi =10.1159/000056945  }}</ref><ref name="pmid11226231">{{cite journal | vauthors = Dolce V, Fiermonte G, Runswick MJ, Palmieri F, Walker JE | title = The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals | journal = Proc Natl Acad Sci U S A | volume = 98 | issue = 5 | pages = 2284–8 |date=Mar 2001 | pmid = 11226231 | pmc = 30130 | doi = 10.1073/pnas.031430998 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC25A19 solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=60386| accessdate = }}</ref>
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-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19
- | HGNCid = 14409
- | Symbol = SLC25A19
- | AltSymbols =; DNC; MCPHA; MUP1
- | OMIM = 606521
- | ECnumber =
- | Homologene = 5982
- | MGIid = 1914533
-  | Function = {{GNF_GO|id=GO:0005215 |text = transporter activity}} {{GNF_GO|id=GO:0005488 |text = binding}} {{GNF_GO|id=GO:0030233 |text = deoxynucleotide transmembrane transporter activity}}
- | Component = {{GNF_GO|id=GO:0005739 |text = mitochondrion}} {{GNF_GO|id=GO:0005743 |text = mitochondrial inner membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
- | Process = {{GNF_GO|id=GO:0006810 |text = transport}} {{GNF_GO|id=GO:0030302 |text = deoxynucleotide transport}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 60386
-    | Hs_Ensembl = ENSG00000125454
-    | Hs_RefseqProtein = NP_068380
-    | Hs_RefseqmRNA = NM_021734
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 17
-    | Hs_GenLoc_start = 70780669
-    | Hs_GenLoc_end = 70797109
-    | Hs_Uniprot = Q9HC21
-    | Mm_EntrezGene = 67283
-    | Mm_Ensembl = ENSMUSG00000020744
-    | Mm_RefseqmRNA = NM_026071
-    | Mm_RefseqProtein = NP_080347
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 11
-    | Mm_GenLoc_start = 115431073
-    | Mm_GenLoc_end = 115444235
-    | Mm_Uniprot = Q80XJ6
-  }}
-}}
-'''Solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19''', also known as '''SLC25A19''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SLC25A19 solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=60386| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
 ==See also==
@@ Line 57: / Line 6: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
-{{PBB_Further_reading
+*{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
-| citations =
+*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  }}
-*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
+*{{cite journal   |vauthors=Rosenberg MJ, Agarwala R, Bouffard G, etal |title=Mutant deoxynucleotide carrier is associated with congenital microcephaly |journal=Nat. Genet. |volume=32 |issue= 1 |pages= 175–9 |year= 2002 |pmid= 12185364 |doi= 10.1038/ng948 }}
-*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Dolce V, Fiermonte G, Runswick MJ, ''et al.'' |title=The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 5 |pages= 2284-8 |year= 2001 |pmid= 11226231 |doi= 10.1073/pnas.031430998 }}
+*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
-*{{cite journal  | author=Iacobazzi V, Ventura M, Fiermonte G, ''et al.'' |title=Genomic organization and mapping of the gene (SLC25A19) encoding the human mitochondrial deoxynucleotide carrier (DNC). |journal=Cytogenet. Cell Genet. |volume=93 |issue= 1-2 |pages= 40-2 |year= 2001 |pmid= 11474176 |doi=  }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Rosenberg MJ, Agarwala R, Bouffard G, ''et al.'' |title=Mutant deoxynucleotide carrier is associated with congenital microcephaly. |journal=Nat. Genet. |volume=32 |issue= 1 |pages= 175-9 |year= 2002 |pmid= 12185364 |doi= 10.1038/ng948 }}
+*{{cite journal   |vauthors= Carrisi C, Antonucci D, etal |title= Transport of platinum bonded nucleotides into proteoliposomes, mediated by Drosophila melanogaster thiamine pyrophosphate carrier protein (DmTpc1). |journal= j.jinorgbio |volume=130 |pages= 1172 |year= 2013 |pmid=    24148759 |doi= 10.1016/j.jinorgbio.2013.09.012}}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Lam W, Chen C, Ruan S, etal |title=Expression of deoxynucleotide carrier is not associated with the mitochondrial DNA depletion caused by anti-HIV dideoxynucleoside analogs and mitochondrial dNTP uptake |journal=Mol. Pharmacol. |volume=67 |issue= 2 |pages= 408–16 |year= 2005 |pmid= 15539640 |doi= 10.1124/mol.104.007120 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal   |vauthors=Otsuki T, Ota T, Nishikawa T, etal |title=Signal sequence and keyword trap ''in silico'' for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Lindhurst MJ, Fiermonte G, Song S, etal |title=Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 43 |pages= 15927–32 |year= 2006 |pmid= 17035501 |doi= 10.1073/pnas.0607661103  | pmc=1595310 }}
-*{{cite journal  | author=Lam W, Chen C, Ruan S, ''et al.'' |title=Expression of deoxynucleotide carrier is not associated with the mitochondrial DNA depletion caused by anti-HIV dideoxynucleoside analogs and mitochondrial dNTP uptake. |journal=Mol. Pharmacol. |volume=67 |issue= 2 |pages= 408-16 |year= 2005 |pmid= 15539640 |doi= 10.1124/mol.104.007120 }}
+*{{cite journal   |vauthors=Iacopetta D, Carrisi C, et al. |title=The biochemical properties of the mitochondrial thiamine pyrophosphate carrier from Drosophila melanogaster. |journal= FEBS J |volume=277 |pages= 1172 |year= 2010 |pmid=20121944 |doi= 10.1111/j.1742-4658.2009.07550.x }}
-*{{cite journal  | author=Otsuki T, Ota T, Nishikawa T, ''et al.'' |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117-26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
-*{{cite journal  | author=Lindhurst MJ, Fiermonte G, Song S, ''et al.'' |title=Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 43 |pages= 15927-32 |year= 2006 |pmid= 17035501 |doi= 10.1073/pnas.0607661103 }}
-}}
 {{refend}}
-{{membrane-protein-stub}}
+==External links==
+* [https://www.ncbi.nlm.nih.gov/books/NBK1365/  GeneReviews/NCBI/NIH/UW entry on Amish Lethal Microcephaly]
+* [https://www.ncbi.nlm.nih.gov/omim/220500,606521,607196,606521,607196  OMIM entries on Amish Lethal Microcephaly]
 {{Membrane transport proteins}}
 [[Category:Solute carrier family]]
-{{WikiDoc Sources}}
+{{membrane-protein-stub}}

SLC25A19: Difference between revisions

Latest revision as of 06:29, 11 September 2017

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See also

References

Further reading

External links

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