SLC15A2: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Robot: Automated text replacement (-{{reflist}} +{{reflist|2}}, -<references /> +{{reflist|2}}, -{{WikiDoc Cardiology Network Infobox}} +))
 
m (Bot: HTTP→HTTPS)
 
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Solute carrier family 15 (H+/peptide transporter), member 2''', also known as '''SLC15A2''', is a [[human]] [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SLC15A2 solute carrier family 15 (H+/peptide transporter), member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6565| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Solute carrier family 15 (H+/peptide transporter), member 2
| HGNCid = 10921
| Symbol = SLC15A2
| AltSymbols =; PEPT2
| OMIM = 602339
| ECnumber = 
| Homologene = 56912
| MGIid = 1890457
| GeneAtlas_image1 = PBB_GE_SLC15A2_205317_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_SLC15A2_205316_at_tn.png
| Function = {{GNF_GO|id=GO:0005215 |text = transporter activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0015198 |text = oligopeptide transporter activity}} {{GNF_GO|id=GO:0015293 |text = symporter activity}} {{GNF_GO|id=GO:0015333 |text = peptide:hydrogen symporter activity}} {{GNF_GO|id=GO:0015334 |text = high affinity oligopeptide transporter activity}}
| Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0006857 |text = oligopeptide transport}} {{GNF_GO|id=GO:0015031 |text = protein transport}} {{GNF_GO|id=GO:0015893 |text = drug transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6565
    | Hs_Ensembl = ENSG00000163406
    | Hs_RefseqProtein = NP_066568
    | Hs_RefseqmRNA = NM_021082
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 3
    | Hs_GenLoc_start = 123095977
    | Hs_GenLoc_end = 123143147
    | Hs_Uniprot = Q16348
    | Mm_EntrezGene = 57738
    | Mm_Ensembl = ENSMUSG00000022899
    | Mm_RefseqmRNA = NM_021301
    | Mm_RefseqProtein = NP_067276
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 16
    | Mm_GenLoc_start = 36669420
    | Mm_GenLoc_end = 36704201
    | Mm_Uniprot = Q80XC0
  }}
}}
'''Solute carrier family 15 (H+/peptide transporter), member 2''', also known as '''SLC15A2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SLC15A2 solute carrier family 15 (H+/peptide transporter), member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6565| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Line 59: Line 12:


==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
Line 65: Line 18:
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Liu W, Liang R, Ramamoorthy S, ''et al.'' |title=Molecular cloning of PEPT 2, a new member of the H+/peptide cotransporter family, from human kidney. |journal=Biochim. Biophys. Acta |volume=1235 |issue= 2 |pages= 461-6 |year= 1995 |pmid= 7756356 |doi=  }}
*{{cite journal   |vauthors=Liu W, Liang R, Ramamoorthy S, etal |title=Molecular cloning of PEPT 2, a new member of the H+/peptide cotransporter family, from human kidney. |journal=Biochim. Biophys. Acta |volume=1235 |issue= 2 |pages= 461–6 |year= 1995 |pmid= 7756356 |doi=10.1016/0005-2736(95)80036-F }}
*{{cite journal  | author=Döring F, Martini C, Walter J, Daniel H |title=Importance of a small N-terminal region in mammalian peptide transporters for substrate affinity and function. |journal=J. Membr. Biol. |volume=186 |issue= 2 |pages= 55-62 |year= 2002 |pmid= 11944083 |doi= 10.1007/s00232-001-0135-9 }}
*{{cite journal  | vauthors=Döring F, Martini C, Walter J, Daniel H |title=Importance of a small N-terminal region in mammalian peptide transporters for substrate affinity and function. |journal=J. Membr. Biol. |volume=186 |issue= 2 |pages= 55–62 |year= 2002 |pmid= 11944083 |doi= 10.1007/s00232-001-0135-9 }}
*{{cite journal  | author=Alcorn J, Lu X, Moscow JA, McNamara PJ |title=Transporter gene expression in lactating and nonlactating human mammary epithelial cells using real-time reverse transcription-polymerase chain reaction. |journal=J. Pharmacol. Exp. Ther. |volume=303 |issue= 2 |pages= 487-96 |year= 2002 |pmid= 12388627 |doi= 10.1124/jpet.102.038315 }}
*{{cite journal  | vauthors=Alcorn J, Lu X, Moscow JA, McNamara PJ |title=Transporter gene expression in lactating and nonlactating human mammary epithelial cells using real-time reverse transcription-polymerase chain reaction. |journal=J. Pharmacol. Exp. Ther. |volume=303 |issue= 2 |pages= 487–96 |year= 2002 |pmid= 12388627 |doi= 10.1124/jpet.102.038315 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal  | author=Groneberg DA |title=[Expression, localization and functional aspects of the peptide transporter PEPT2 in the normal respiratory tract and in cystic fibrosis] |journal=Pneumologie (Stuttgart, Germany) |volume=57 |issue= 2 |pages= 104-5 |year= 2003 |pmid= 12579467 |doi= 10.1055/s-2003-37158 }}
*{{cite journal  | author=Groneberg DA |title=[Expression, localization and functional aspects of the peptide transporter PEPT2 in the normal respiratory tract and in cystic fibrosis] |journal=Pneumologie (Stuttgart, Germany) |volume=57 |issue= 2 |pages= 104–5 |year= 2003 |pmid= 12579467 |doi= 10.1055/s-2003-37158 }}
*{{cite journal  | author=Terada T, Irie M, Okuda M, Inui K |title=Genetic variant Arg57His in human H+/peptide cotransporter 2 causes a complete loss of transport function. |journal=Biochem. Biophys. Res. Commun. |volume=316 |issue= 2 |pages= 416-20 |year= 2004 |pmid= 15020234 |doi= 10.1016/j.bbrc.2004.02.063 }}
*{{cite journal  | vauthors=Terada T, Irie M, Okuda M, Inui K |title=Genetic variant Arg57His in human H+/peptide cotransporter 2 causes a complete loss of transport function. |journal=Biochem. Biophys. Res. Commun. |volume=316 |issue= 2 |pages= 416–20 |year= 2004 |pmid= 15020234 |doi= 10.1016/j.bbrc.2004.02.063 }}
*{{cite journal  | author=Pinsonneault J, Nielsen CU, Sadée W |title=Genetic variants of the human H+/dipeptide transporter PEPT2: analysis of haplotype functions. |journal=J. Pharmacol. Exp. Ther. |volume=311 |issue= 3 |pages= 1088-96 |year= 2005 |pmid= 15282265 |doi= 10.1124/jpet.104.073098 }}
*{{cite journal  | vauthors=Pinsonneault J, Nielsen CU, Sadée W |title=Genetic variants of the human H+/dipeptide transporter PEPT2: analysis of haplotype functions. |journal=J. Pharmacol. Exp. Ther. |volume=311 |issue= 3 |pages= 1088–96 |year= 2005 |pmid= 15282265 |doi= 10.1124/jpet.104.073098 }}
*{{cite journal | author=Bahadduri PM, D'Souza VM, Pinsonneault JK, ''et al.'' |title=Functional characterization of the peptide transporter PEPT2 in primary cultures of human upper airway epithelium. |journal=Am. J. Respir. Cell Mol. Biol. |volume=32 |issue= 4 |pages= 319-25 |year= 2005 |pmid= 15626774 |doi= 10.1165/rcmb.2004-0322OC }}
*{{cite journal   |vauthors=Bahadduri PM, D'Souza VM, Pinsonneault JK, etal |title=Functional characterization of the peptide transporter PEPT2 in primary cultures of human upper airway epithelium. |journal=Am. J. Respir. Cell Mol. Biol. |volume=32 |issue= 4 |pages= 319–25 |year= 2005 |pmid= 15626774 |doi= 10.1165/rcmb.2004-0322OC }}
*{{cite journal | author=Zhang EY, Emerick RM, Pak YA, ''et al.'' |title=Comparison of human and monkey peptide transporters: PEPT1 and PEPT2. |journal=Mol. Pharm. |volume=1 |issue= 3 |pages= 201-10 |year= 2005 |pmid= 15981923 |doi=  }}
*{{cite journal   |vauthors=Zhang EY, Emerick RM, Pak YA, etal |title=Comparison of human and monkey peptide transporters: PEPT1 and PEPT2. |journal=Mol. Pharm. |volume=1 |issue= 3 |pages= 201–10 |year= 2005 |pmid= 15981923 |doi=10.1021/mp0499712 }}
*{{cite journal | author=Noshiro R, Anzai N, Sakata T, ''et al.'' |title=The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity. |journal=Kidney Int. |volume=70 |issue= 2 |pages= 275-82 |year= 2006 |pmid= 16738539 |doi= 10.1038/sj.ki.5001522 }}
*{{cite journal   |vauthors=Noshiro R, Anzai N, Sakata T, etal |title=The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity. |journal=Kidney Int. |volume=70 |issue= 2 |pages= 275–82 |year= 2006 |pmid= 16738539 |doi= 10.1038/sj.ki.5001522 }}
*{{cite journal  |vauthors=Søndergaard H, Bravo S, Nielsen CU, etal |title=Cloning of the pig PEPT2 (pPEPT2) and characterization of the effects of epidermal growth factor (EGF) on pPEPT2-mediated peptide uptake in the renal porcine cell line LLC-PK1. |journal=Eur. J. Pharm. Sci. |volume=33 |issue= 4 |pages= 332–42 |year= 2008 |pmid= 18295462|doi= 10.1016/j.ejps.2008.01.001 }}
}}
}}
{{refend}}
{{refend}}


{{membrane-protein-stub}}
{{Membrane transport proteins}}
{{Membrane transport proteins}}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
[[Category:Solute carrier family]]
[[Category:Solute carrier family]]
{{WikiDoc Sources}}
 
 
{{membrane-protein-stub}}

Latest revision as of 06:26, 11 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Solute carrier family 15 (H+/peptide transporter), member 2, also known as SLC15A2, is a human gene.[1]


See also

References

  1. ↑ "Entrez Gene: SLC15A2 solute carrier family 15 (H+/peptide transporter), member 2".

Further reading

  • Liu W, Liang R, Ramamoorthy S, et al. (1995). "Molecular cloning of PEPT 2, a new member of the H+/peptide cotransporter family, from human kidney". Biochim. Biophys. Acta. 1235 (2): 461–6. doi:10.1016/0005-2736(95)80036-F. PMID 7756356.
  • Döring F, Martini C, Walter J, Daniel H (2002). "Importance of a small N-terminal region in mammalian peptide transporters for substrate affinity and function". J. Membr. Biol. 186 (2): 55–62. doi:10.1007/s00232-001-0135-9. PMID 11944083.
  • Alcorn J, Lu X, Moscow JA, McNamara PJ (2002). "Transporter gene expression in lactating and nonlactating human mammary epithelial cells using real-time reverse transcription-polymerase chain reaction". J. Pharmacol. Exp. Ther. 303 (2): 487–96. doi:10.1124/jpet.102.038315. PMID 12388627.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Groneberg DA (2003). "[Expression, localization and functional aspects of the peptide transporter PEPT2 in the normal respiratory tract and in cystic fibrosis]". Pneumologie (Stuttgart, Germany). 57 (2): 104–5. doi:10.1055/s-2003-37158. PMID 12579467.
  • Terada T, Irie M, Okuda M, Inui K (2004). "Genetic variant Arg57His in human H+/peptide cotransporter 2 causes a complete loss of transport function". Biochem. Biophys. Res. Commun. 316 (2): 416–20. doi:10.1016/j.bbrc.2004.02.063. PMID 15020234.
  • Pinsonneault J, Nielsen CU, Sadée W (2005). "Genetic variants of the human H+/dipeptide transporter PEPT2: analysis of haplotype functions". J. Pharmacol. Exp. Ther. 311 (3): 1088–96. doi:10.1124/jpet.104.073098. PMID 15282265.
  • Bahadduri PM, D'Souza VM, Pinsonneault JK, et al. (2005). "Functional characterization of the peptide transporter PEPT2 in primary cultures of human upper airway epithelium". Am. J. Respir. Cell Mol. Biol. 32 (4): 319–25. doi:10.1165/rcmb.2004-0322OC. PMID 15626774.
  • Zhang EY, Emerick RM, Pak YA, et al. (2005). "Comparison of human and monkey peptide transporters: PEPT1 and PEPT2". Mol. Pharm. 1 (3): 201–10. doi:10.1021/mp0499712. PMID 15981923.
  • Noshiro R, Anzai N, Sakata T, et al. (2006). "The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity". Kidney Int. 70 (2): 275–82. doi:10.1038/sj.ki.5001522. PMID 16738539.
  • Søndergaard H, Bravo S, Nielsen CU, et al. (2008). "Cloning of the pig PEPT2 (pPEPT2) and characterization of the effects of epidermal growth factor (EGF) on pPEPT2-mediated peptide uptake in the renal porcine cell line LLC-PK1". Eur. J. Pharm. Sci. 33 (4): 332–42. doi:10.1016/j.ejps.2008.01.001. PMID 18295462.


Retrieved from "https://www.wikidoc.org/index.php?title=SLC15A2&oldid=1413282"