Riedel's thyroiditis

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Riedel's thyroiditis
ICD-10 E06.5
ICD-9 245.3
DiseasesDB 11590
eMedicine med/2036 

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Riedel's thyroiditis, also called Riedel's struma is a chronic form of thyroiditis.

Pathophysiology

Riedel's thyroiditis is characterized by a replacement of the normal thyroid parenchyma by a dense fibrosis that invades adjacent structures of the neck and extends beyond the thyroid capsule.[1] This makes the thyroid gland stone-hard and fixed to adjacent structures.

A shared mechanism with retroperitoneal fibrosis and sclerosing cholangitis has been suggested.[2]

Prevalence

Riedel's thyroiditis is classified as rare. Most patients remain euthyroid, but approximately 30% of patients become hypothyroid and very few patients are hyperthyroid. It is most seen in women.[3]

Treatment

Tamoxifen has been proposed as part of a treatment plan.[4]

Eponym

It is named for Bernhard Riedel. He first recognized the disease In 1883 and published its description in 1896.[5][6]

References

  1. Cho MH, Kim CS, Park JS; et al. (2007). "Riedel's thyroiditis in a patient with recurrent subacute thyroiditis: a case report and review of the literature". Endocr. J. 54 (4): 559–62. PMID 17603227. Unknown parameter |month= ignored (help)
  2. De Boer WA (1993). "Riedel's thyroiditis, retroperitoneal fibrosis, and sclerosing cholangitis: diseases with one pathogenesis?". Gut. 34 (5): 714. PMC 1374200. PMID 8504980. Unknown parameter |month= ignored (help)
  3. eMedicine
  4. Dabelic N, Jukic T, Labar Z, Novosel SA, Matesa N, Kusic Z (2003). "Riedel's thyroiditis treated with tamoxifen" (PDF). Croat. Med. J. 44 (2): 239–41. PMID 12698518. Unknown parameter |month= ignored (help)
  5. B. M. C. L. Riedel. Die chronische, zur Bildung eisenharter Tumoren führende Entzündung der Schilddrüse. Verhandlungen der deutschen Gesellschaft für Chirurgie, 1896, 25: 101-105.
  6. synd/3242 at Who Named It



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