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==Overview==
==Overview==
[[Rheumatoid arthritis]] signs and symptoms are noticed by Augustin Jacob Landre-Beauvais, a resident physician at the Saltpetriere asylum in France, in 1800. He named it as Goutte Asthenique Primitive or Primary Asthenic [[Gout]]. The name [[Rheumatoid arthritis]] coined by Archibald Garrod in 1890. [[HLA-DR]] locus present on [[chromosome]] 6 is involved in the pathogenesis of rheumatoid arthritis.
Signs and symptoms associated with [[rheumatoid arthritis]] were noticed by Augustin Jacob Landre-Beauvais, a resident physician at the Saltpetriere asylum in France, in 1800. He named this disease as Goutte Asthenique Primitive or Primary Asthenic [[Gout]]. The name [[Rheumatoid arthritis]] was coined by Archibald Garrod in 1890. In 1970, [[human leukocyte antigen]] (HLA) was first implicated in the pathogenesis of [[rheumatoid arthritis]].
 
==Historical Perspective==
==Historical Perspective==


===Discovery===
===Discovery===
*[[Rheumatoid arthritis]] signs and symptoms are noticed by Augustin Jacob Landre-Beauvais, a resident physician at the Saltpetriere asylum in France, in 1800, He named it as  Goutte Asthenique Primitive or Primary Asthenic [[Gout]].<ref name="pmid11324929">{{cite journal |vauthors=Landré-Beauvais AJ |title=The first description of rheumatoid arthritis. Unabridged text of the doctoral dissertation presented in 1800 |journal=Joint Bone Spine |volume=68 |issue=2 |pages=130–43 |date=March 2001 |pmid=11324929 |doi= |url=}}</ref>  
*[[Rheumatoid arthritis]] associated signs and symptoms were noticed by Augustin Jacob Landre-Beauvais, a resident physician at the Saltpetriere asylum in France, in 1800. He named [[rheumatoid arthritis]] as  Goutte Asthenique Primitive or Primary Asthenic [[Gout]].<ref name="pmid11324929">{{cite journal |vauthors=Landré-Beauvais AJ |title=The first description of rheumatoid arthritis. Unabridged text of the doctoral dissertation presented in 1800 |journal=Joint Bone Spine |volume=68 |issue=2 |pages=130–43 |date=March 2001 |pmid=11324929 |doi= |url=}}</ref>  
*In 1890, Archibald Garrod coined the name '''Rheumatoid arthritis'''<nowiki/>'<ref name="pmid11600751">{{cite journal |vauthors=Storey GD |title=Alfred Baring Garrod (1819-1907) |journal=Rheumatology (Oxford) |volume=40 |issue=10 |pages=1189–90 |date=October 2001 |pmid=11600751 |doi= |url=}}</ref>
*In 1890, Archibald Garrod coined the name '''Rheumatoid arthritis'''.<nowiki/><ref name="pmid11600751">{{cite journal |vauthors=Storey GD |title=Alfred Baring Garrod (1819-1907) |journal=Rheumatology (Oxford) |volume=40 |issue=10 |pages=1189–90 |date=October 2001 |pmid=11600751 |doi= |url=}}</ref>
*[[Major histocompatibility complex]] (MHC class II) cell surface receptors encoded by alleles of the [[HLA-DR]] locus on [[chromosome]] 6 were first implicated in the [[pathogenesis]] of [[rheumatoid arthritis]].<ref name="pmid9608321">{{cite journal |vauthors=Reveille JD |title=The genetic contribution to the pathogenesis of rheumatoid arthritis |journal=Curr Opin Rheumatol |volume=10 |issue=3 |pages=187–200 |date=May 1998 |pmid=9608321 |doi= |url=}}</ref><ref name="pmid21176794">{{cite journal |vauthors=Entezami P, Fox DA, Clapham PJ, Chung KC |title=Historical perspective on the etiology of rheumatoid arthritis |journal=Hand Clin |volume=27 |issue=1 |pages=1–10 |date=February 2011 |pmid=21176794 |pmc=3119866 |doi=10.1016/j.hcl.2010.09.006 |url=}}</ref>
*In 1970, [[human leukocyte antigen]] (HLA) was first implicated in the pathogenesis of [[rheumatoid arthritis]].<ref name="pmid869952">{{cite journal |vauthors=McMichael AJ, Sasazuki T, McDevitt HO, Payne RO |title=Increased frequency of HLA-Cw3 and HLA-Dw4 in rheumatoid arthritis |journal=Arthritis Rheum. |volume=20 |issue=5 |pages=1037–42 |date=June 1977 |pmid=869952 |doi= |url=}}</ref><ref name="pmid147420">{{cite journal |vauthors=Stastny P |title=Association of the B-cell alloantigen DRw4 with rheumatoid arthritis |journal=N. Engl. J. Med. |volume=298 |issue=16 |pages=869–71 |date=April 1978 |pmid=147420 |doi=10.1056/NEJM197804202981602 |url=}}</ref>


==References==
==References==

Latest revision as of 15:13, 23 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]

Overview

Signs and symptoms associated with rheumatoid arthritis were noticed by Augustin Jacob Landre-Beauvais, a resident physician at the Saltpetriere asylum in France, in 1800. He named this disease as Goutte Asthenique Primitive or Primary Asthenic Gout. The name Rheumatoid arthritis was coined by Archibald Garrod in 1890. In 1970, human leukocyte antigen (HLA) was first implicated in the pathogenesis of rheumatoid arthritis.

Historical Perspective

Discovery

References

  1. Landré-Beauvais AJ (March 2001). "The first description of rheumatoid arthritis. Unabridged text of the doctoral dissertation presented in 1800". Joint Bone Spine. 68 (2): 130–43. PMID 11324929.
  2. Storey GD (October 2001). "Alfred Baring Garrod (1819-1907)". Rheumatology (Oxford). 40 (10): 1189–90. PMID 11600751.
  3. McMichael AJ, Sasazuki T, McDevitt HO, Payne RO (June 1977). "Increased frequency of HLA-Cw3 and HLA-Dw4 in rheumatoid arthritis". Arthritis Rheum. 20 (5): 1037–42. PMID 869952.
  4. Stastny P (April 1978). "Association of the B-cell alloantigen DRw4 with rheumatoid arthritis". N. Engl. J. Med. 298 (16): 869–71. doi:10.1056/NEJM197804202981602. PMID 147420.

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