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(New page: {{Rheumatic fever}} {{CMG}}; '''Associate Editor(s)-In-Chief:''' Varun Kumar, M.B.B.S. ==Inflammatory Markers== The following inflammatory markers are often elevated: *[[Complete Blo...)
 
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==Diagnosis of Streptococcus Pharyngitis==
==Diagnosis of Streptococcus Pharyngitis==
*Throat culture for group A beta hemolytic streptococci may be performed. However many patients may have negative culture by the time rheumatic fever develops<ref name="pmid1404745">{{cite journal| author=| title=Guidelines for the diagnosis of rheumatic fever. Jones Criteria, 1992 update. Special Writing Group of the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young of the American Heart Association. | journal=JAMA | year= 1992 | volume= 268 | issue= 15 | pages= 2069-73 | pmid=1404745 | doi= | pmc= | url= }} </ref>.
*[[Throat culture]] for group A beta hemolytic streptococci may be performed. However many patients may have negative culture by the time rheumatic fever develops<ref name="pmid1404745">{{cite journal| author=| title=Guidelines for the diagnosis of rheumatic fever. Jones Criteria, 1992 update. Special Writing Group of the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young of the American Heart Association. | journal=JAMA | year= 1992 | volume= 268 | issue= 15 | pages= 2069-73 | pmid=1404745 | doi= | pmc= | url= }} </ref>.
*Rapid streptococcal antigen test
*Rapid streptococcal antigen test is quicker. However, it has a lower sensitivity (70%) and statistically equal specificity (98%) as throat culture<ref name="pmid19275067">{{cite journal| author=Choby BA| title=Diagnosis and treatment of streptococcal pharyngitis. | journal=Am Fam Physician | year= 2009 | volume= 79 | issue= 5 | pages= 383-90 | pmid=19275067 | doi= | pmc= | url= }} </ref>. Therefore, negative test results rules out streptococcal infection.
*Elevated or rising antistreptolysin O antibody titer
*Elevated or rising [[antistreptolysin O]] antibody titer.


==References==
==References==

Revision as of 19:56, 16 September 2011

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S.

Inflammatory Markers

The following inflammatory markers are often elevated:

Diagnosis of Streptococcus Pharyngitis

  • Throat culture for group A beta hemolytic streptococci may be performed. However many patients may have negative culture by the time rheumatic fever develops[1].
  • Rapid streptococcal antigen test is quicker. However, it has a lower sensitivity (70%) and statistically equal specificity (98%) as throat culture[2]. Therefore, negative test results rules out streptococcal infection.
  • Elevated or rising antistreptolysin O antibody titer.

References

  1. "Guidelines for the diagnosis of rheumatic fever. Jones Criteria, 1992 update. Special Writing Group of the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young of the American Heart Association". JAMA. 268 (15): 2069–73. 1992. PMID 1404745.
  2. Choby BA (2009). "Diagnosis and treatment of streptococcal pharyngitis". Am Fam Physician. 79 (5): 383–90. PMID 19275067.

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