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{{Renal Amyloidosis}}
{{Renal Amyloidosis}}
{{CMG}}; {{AE}}  
{{CMG}}; {{AE}} {{SHH}}


==Overview==
==Overview==

Revision as of 19:36, 22 June 2018

Renal amyloidosis Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]

Overview

Other Diagnostic Studies

Kidney biopsy

  • Kidney biopsy can represent amyloid deposition as vascular, tubulo-interstitial and/or glomerular deposits.[1]
  • In evaluation of kidney biopsy specimens, types of amyloidogenic proteins can be discovered.[2]

Congo red staining

  • All types of amyloidogenic proteins show affinity for Congo red dye, which demonstrates as:[3]
    • Orange-red appearance by normal light microscopy
    • Apple-green birefringence upon polarized light

References

  1. von Hutten H, Mihatsch M, Lobeck H, Rudolph B, Eriksson M, Röcken C (August 2009). "Prevalence and origin of amyloid in kidney biopsies". Am. J. Surg. Pathol. 33 (8): 1198–205. doi:10.1097/PAS.0b013e3181abdfa7. PMID 19561448.
  2. Khalighi MA, Dean Wallace W, Palma-Diaz MF (April 2014). "Amyloid nephropathy". Clin Kidney J. 7 (2): 97–106. doi:10.1093/ckj/sfu021. PMC 4377792. PMID 25852856.
  3. Khalighi MA, Dean Wallace W, Palma-Diaz MF (April 2014). "Amyloid nephropathy". Clin Kidney J. 7 (2): 97–106. doi:10.1093/ckj/sfu021. PMC 4377792. PMID 25852856.

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