Radiation proctitis primary prevention: Difference between revisions
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Primary prevention strategies include: <ref name="pmid16170489">{{cite journal| author=Hille A, Christiansen H, Pradier O, Hermann RM, Siekmeyer B, Weiss E et al.| title=Effect of pentoxifylline and tocopherol on radiation proctitis/enteritis. | journal=Strahlenther Onkol | year= 2005 | volume= 181 | issue= 9 | pages= 606-14 | pmid=16170489 | doi=10.1007/s00066-005-1390-y | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16170489 }}</ref> | Primary prevention strategies include: <ref name="pmid16170489">{{cite journal| author=Hille A, Christiansen H, Pradier O, Hermann RM, Siekmeyer B, Weiss E et al.| title=Effect of pentoxifylline and tocopherol on radiation proctitis/enteritis. | journal=Strahlenther Onkol | year= 2005 | volume= 181 | issue= 9 | pages= 606-14 | pmid=16170489 | doi=10.1007/s00066-005-1390-y | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16170489 }}</ref> | ||
* modifications of radiation techniques and doses (Ex: intensity-modulated radiation therapy, image-guided radiation therapy decreases the rectal toxicity while maximizing the dose to the tumor.)<ref name="pmid17692976">{{cite journal| author=Fonteyne V, De Neve W, Villeirs G, De Wagter C, De Meerleer G| title=Late radiotherapy-induced lower intestinal toxicity (RILIT) of intensity-modulated radiotherapy for prostate cancer: the need for adapting toxicity scales and the appearance of the sigmoid colon as co-responsible organ for lower intestinal toxicity. | journal=Radiother Oncol | year= 2007 | volume= 84 | issue= 2 | pages= 156-63 | pmid=17692976 | doi=10.1016/j.radonc.2007.06.013 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17692976 }}</ref> | * modifications of radiation techniques and doses (Ex: intensity-modulated radiation therapy, image-guided radiation therapy decreases the rectal toxicity while maximizing the dose to the tumor.)<ref name="pmid17692976">{{cite journal| author=Fonteyne V, De Neve W, Villeirs G, De Wagter C, De Meerleer G| title=Late radiotherapy-induced lower intestinal toxicity (RILIT) of intensity-modulated radiotherapy for prostate cancer: the need for adapting toxicity scales and the appearance of the sigmoid colon as co-responsible organ for lower intestinal toxicity. | journal=Radiother Oncol | year= 2007 | volume= 84 | issue= 2 | pages= 156-63 | pmid=17692976 | doi=10.1016/j.radonc.2007.06.013 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17692976 }}</ref> | ||
* Identifying high risk patients<ref name="pmid24974847">{{cite journal| author=Fachal L, Gómez-Caamaño A, Barnett GC, Peleteiro P, Carballo AM, Calvo-Crespo P et al.| title=A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24.1. | journal=Nat Genet | year= 2014 | volume= 46 | issue= 8 | pages= 891-4 | pmid=24974847 | doi=10.1038/ng.3020 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24974847 }}</ref> | * Identifying high risk patients, based on genomic study helps taking extra precautions in those patients<ref name="pmid24974847">{{cite journal| author=Fachal L, Gómez-Caamaño A, Barnett GC, Peleteiro P, Carballo AM, Calvo-Crespo P et al.| title=A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24.1. | journal=Nat Genet | year= 2014 | volume= 46 | issue= 8 | pages= 891-4 | pmid=24974847 | doi=10.1038/ng.3020 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24974847 }}</ref><ref name="pmid21861849">{{cite journal| author=West CM, Barnett GC| title=Genetics and genomics of radiotherapy toxicity: towards prediction. | journal=Genome Med | year= 2011 | volume= 3 | issue= 8 | pages= 52 | pmid=21861849 | doi=10.1186/gm268 | pmc=3238178 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21861849 }}</ref> | ||
==References== | ==References== | ||
Revision as of 06:05, 10 June 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
Overview
Primary Prevention
Primary prevention strategies include: [1]
- modifications of radiation techniques and doses (Ex: intensity-modulated radiation therapy, image-guided radiation therapy decreases the rectal toxicity while maximizing the dose to the tumor.)[2]
- Identifying high risk patients, based on genomic study helps taking extra precautions in those patients[3][4]
References
- ↑ Hille A, Christiansen H, Pradier O, Hermann RM, Siekmeyer B, Weiss E; et al. (2005). "Effect of pentoxifylline and tocopherol on radiation proctitis/enteritis". Strahlenther Onkol. 181 (9): 606–14. doi:10.1007/s00066-005-1390-y. PMID 16170489.
- ↑ Fonteyne V, De Neve W, Villeirs G, De Wagter C, De Meerleer G (2007). "Late radiotherapy-induced lower intestinal toxicity (RILIT) of intensity-modulated radiotherapy for prostate cancer: the need for adapting toxicity scales and the appearance of the sigmoid colon as co-responsible organ for lower intestinal toxicity". Radiother Oncol. 84 (2): 156–63. doi:10.1016/j.radonc.2007.06.013. PMID 17692976.
- ↑ Fachal L, Gómez-Caamaño A, Barnett GC, Peleteiro P, Carballo AM, Calvo-Crespo P; et al. (2014). "A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24.1". Nat Genet. 46 (8): 891–4. doi:10.1038/ng.3020. PMID 24974847.
- ↑ West CM, Barnett GC (2011). "Genetics and genomics of radiotherapy toxicity: towards prediction". Genome Med. 3 (8): 52. doi:10.1186/gm268. PMC 3238178. PMID 21861849.