RGS7

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Regulator of G-protein signalling 7
File:PBB Protein RGS7 image.jpg
PDB rendering based on 2a72.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols RGS7 ;
External IDs Template:OMIM5 Template:MGI HomoloGene2193
RNA expression pattern
File:PBB GE RGS7 206290 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Regulator of G-protein signalling 7, also known as RGS7, is a human gene.[1]


References

  1. "Entrez Gene: RGS7 regulator of G-protein signalling 7".

Further reading

  • Koelle MR, Horvitz HR (1996). "EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins". Cell. 84 (1): 115–25. PMID 8548815.
  • Shuey DJ, Betty M, Jones PG; et al. (1998). "RGS7 attenuates signal transduction through the G(alpha q) family of heterotrimeric G proteins in mammalian cells". J. Neurochem. 70 (5): 1964–72. PMID 9572280.
  • Levay K, Cabrera JL, Satpaev DK, Slepak VZ (1999). "Gbeta5 prevents the RGS7-Galphao interaction through binding to a distinct Ggamma-like domain found in RGS7 and other RGS proteins". Proc. Natl. Acad. Sci. U.S.A. 96 (5): 2503–7. PMID 10051672.
  • Saitoh O, Kubo Y, Odagiri M; et al. (1999). "RGS7 and RGS8 differentially accelerate G protein-mediated modulation of K+ currents". J. Biol. Chem. 274 (14): 9899–904. PMID 10092682.
  • Kim E, Arnould T, Sellin L; et al. (1999). "Interaction between RGS7 and polycystin". Proc. Natl. Acad. Sci. U.S.A. 96 (11): 6371–6. PMID 10339594.
  • Snow BE, Betts L, Mangion J; et al. (1999). "Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11". Proc. Natl. Acad. Sci. U.S.A. 96 (11): 6489–94. PMID 10339615.
  • Posner BA, Gilman AG, Harris BA (1999). "Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathways". J. Biol. Chem. 274 (43): 31087–93. PMID 10521509.
  • Benzing T, Yaffe MB, Arnould T; et al. (2000). "14-3-3 interacts with regulator of G protein signaling proteins and modulates their activity". J. Biol. Chem. 275 (36): 28167–72. doi:10.1074/jbc.M002905200. PMID 10862767.
  • Rose JJ, Taylor JB, Shi J; et al. (2000). "RGS7 is palmitoylated and exists as biochemically distinct forms". J. Neurochem. 75 (5): 2103–12. PMID 11032900.
  • Zhang JH, Barr VA, Mo Y; et al. (2001). "Nuclear localization of G protein beta 5 and regulator of G protein signaling 7 in neurons and brain". J. Biol. Chem. 276 (13): 10284–9. doi:10.1074/jbc.M009247200. PMID 11152459.
  • Benzing T, Köttgen M, Johnson M; et al. (2002). "Interaction of 14-3-3 protein with regulator of G protein signaling 7 is dynamically regulated by tumor necrosis factor-alpha". J. Biol. Chem. 277 (36): 32954–62. doi:10.1074/jbc.M200859200. PMID 12077120.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Hunt RA, Edris W, Chanda PK; et al. (2003). "Snapin interacts with the N-terminus of regulator of G protein signaling 7". Biochem. Biophys. Res. Commun. 303 (2): 594–9. PMID 12659861.
  • Witherow DS, Tovey SC, Wang Q; et al. (2003). "G beta 5.RGS7 inhibits G alpha q-mediated signaling via a direct protein-protein interaction". J. Biol. Chem. 278 (23): 21307–13. doi:10.1074/jbc.M212884200. PMID 12670932.
  • Anderson NL, Polanski M, Pieper R; et al. (2004). "The human plasma proteome: a nonredundant list developed by combination of four separate sources". Mol. Cell Proteomics. 3 (4): 311–26. doi:10.1074/mcp.M300127-MCP200. PMID 14718574.
  • Takida S, Fischer CC, Wedegaertner PB (2005). "Palmitoylation and plasma membrane targeting of RGS7 are promoted by alpha o.". Mol. Pharmacol. 67 (1): 132–9. doi:10.1124/mol.104.003418. PMID 15496508.
  • Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  • Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
  • Gregory SG, Barlow KF, McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
  • Drenan RM, Doupnik CA, Jayaraman M; et al. (2006). "R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanism". J. Biol. Chem. 281 (38): 28222–31. doi:10.1074/jbc.M604428200. PMID 16867977.

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