RCP9

Calcitonin gene-related peptide-receptor component protein
Identifiers
Symbols	RCP9 ; RCP; CGRP-RCP; CRCP; MGC111194
External IDs	Template:OMIM5 Template:MGI HomoloGene: 40587
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE RCP9 203898 at tn.png
File:PBB GE RCP9 203899 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Calcitonin gene-related peptide-receptor component protein, also known as RCP9, is a human gene.

This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Further reading

• Yallampalli C, Chauhan M, Thota CS; et al. (2003). "Calcitonin gene-related peptide in pregnancy and its emerging receptor heterogeneity". Trends Endocrinol. Metab. 13 (6): 263–9. PMID 12128288.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Luebke AE, Dahl GP, Roos BA, Dickerson IM (1996). "Identification of a protein that confers calcitonin gene-related peptide responsiveness to oocytes by using a cystic fibrosis transmembrane conductance regulator assay". Proc. Natl. Acad. Sci. U.S.A. 93 (8): 3455–60. PMID 8622957.CS1 maint: Multiple names: authors list (link)
• Balkan W, Oates EL, Howard GA, Roos BA (1999). "Testes exhibit elevated expression of calcitonin gene-related peptide receptor component protein". Endocrinology. 140 (3): 1459–69. PMID 10067875.CS1 maint: Multiple names: authors list (link)
• Evans BN, Rosenblatt MI, Mnayer LO; et al. (2000). "CGRP-RCP, a novel protein required for signal transduction at calcitonin gene-related peptide and adrenomedullin receptors". J. Biol. Chem. 275 (40): 31438–43. doi:10.1074/jbc.M005604200. PMID 10903324.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Prado MA, Evans-Bain B, Oliver KR, Dickerson IM (2002). "The role of the CGRP-receptor component protein (RCP) in adrenomedullin receptor signal transduction". Peptides. 22 (11): 1773–81. PMID 11754963.CS1 maint: Multiple names: authors list (link)
• Moreno MJ, Terrón JA, Stanimirovic DB; et al. (2002). "Characterization of calcitonin gene-related peptide (CGRP) receptors and their receptor-activity-modifying proteins (RAMPs) in human brain microvascular and astroglial cells in culture". Neuropharmacology. 42 (2): 270–80. PMID 11804624.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Harzenetter MD, Keller U, Beer S; et al. (2002). "Regulation and function of the CGRP receptor complex in human granulopoiesis". Exp. Hematol. 30 (4): 306–12. PMID 11937264.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hu P, Wu S, Sun Y; et al. (2002). "Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits". Mol. Cell. Biol. 22 (22): 8044–55. PMID 12391170.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Siaut M, Zaros C, Levivier E; et al. (2003). "An Rpb4/Rpb7-like complex in yeast RNA polymerase III contains the orthologue of mammalian CGRP-RCP". Mol. Cell. Biol. 23 (1): 195–205. PMID 12482973.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hasbak P, Saetrum Opgaard O, Eskesen K; et al. (2003). "Investigation of CGRP receptors and peptide pharmacology in human coronary arteries. Characterization with a nonpeptide antagonist". J. Pharmacol. Exp. Ther. 304 (1): 326–33. doi:10.1124/jpet.102.037754. PMID 12490608.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rush J, Moritz A, Lee KA; et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zuccarello D, Morini E, Douzgou S; et al. (2005). "Preliminary data suggest that mutations in the CgRP pathway are not involved in human sporadic cryptorchidism". J. Endocrinol. Invest. 27 (8): 760–4. PMID 15636430.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Krämer HH, Schmidt K, Leis S; et al. (2006). "Angiotensin converting enzyme has an inhibitory role in CGRP metabolism in human skin". Peptides. 27 (4): 917–20. doi:10.1016/j.peptides.2005.08.007. PMID 16406141.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)