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==Overview==
==Overview==
'''Q fever''' is caused by infection with ''[[Coxiella burnetii]]''. This organism is uncommon but may be found in cattle, sheep, goats and other domestic mammals, including cats and dogs.
Q fever is more prevalent in the elderly and in males. It has been a [[notifiable disease]] in the US since 1999. Q fever is underreported, thus scientists cannot reliably assess its incidence.<ref name="pmid18931396">{{cite journal |vauthors=Delsing CE, Kullberg BJ |title=Q fever in the Netherlands: a concise overview and implications of the largest ongoing outbreak |journal=Neth J Med |volume=66 |issue=9 |pages=365–7 |year=2008 |pmid=18931396 |doi= |url=}}</ref>
 
==Epidemiology and demographics==
 
In 1999, Q fever became a notifiable disease in the United States but reporting is not required in many other countries. Because the disease is underreported, scientists cannot reliably assess how many cases of Q fever have actually occurred worldwide.  Many human infections are inapparent.


Cattle, sheep, and goats are the primary reservoirs of C. burnetii.  Infection has been noted in a wide variety of other animals, including other species of livestock and in domesticated pets. Coxiella burnetii does not usually cause clinical disease in these animals, although abortion in goats and sheep has been linked to C. burnetii infection. Organisms are excreted in milk, urine, and feces of infected animals. Most importantly, during birthing the organisms are shed in high numbers within the amniotic fluids and the placenta.  The organisms are resistant to heat, drying, and many common disinfectants. These features enable the bacteria to survive for long periods in the environment. Infection of humans usually occurs by inhalation of these organisms from air that contains airborne barnyard dust contaminated by dried placental material, birth fluids, and excreta of infected herd animals. Humans are often very susceptible to the disease, and very few organisms may be required to cause infection.
==Epidemiology and Demographics==
===Age===
* Q fever is slightly more prevalent in elderly people; however, it is often seen in various age groups.  
* Q fever is occasionally seen in children, especially those who live on a farm.  
* In infected children younger than 3 years old, Q fever usually presents as [[pneumonia]].<ref name="pmid18452690">{{cite journal |vauthors=Hartzell JD, Wood-Morris RN, Martinez LJ, Trotta RF |title=Q fever: epidemiology, diagnosis, and treatment |journal=Mayo Clin. Proc. |volume=83 |issue=5 |pages=574–9 |year=2008 |pmid=18452690 |doi=10.4065/83.5.574 |url=}}</ref>


[[Image:Coxiella burnetii.JPG|thumb|left|C. burnetii, the Q fever causing agent]]
===Gender===
* Due to differing employment rates in typical professions that predispose people to contracting Q fever, men are more often affected than women.<ref name="pmid10515901">{{cite journal |vauthors=Maurin M, Raoult D |title=Q fever |journal=Clin. Microbiol. Rev. |volume=12 |issue=4 |pages=518–53 |year=1999 |pmid=10515901 |pmc=88923 |doi= |url=}}</ref>


The pathogenic agent is to be found everywhere except Antarctica and New Zealand.  
===Developed Countries===
In Europe it appears as hepatitis rather than pneumonia as in the United States. The bacterium is extremely sustainable and infectious: a single organism is able to cause an infection. The common way of infection is inhalation of contaminated dust, contact with contaminated milk, meat, wool and particularly birthing products. Ticks can transfer the pathogenic agent to other animals. Transfer between humans seems extremely rare and has so far been described in very few cases.
* In 1999, Q fever became a [[notifiable disease]] in the United States but reporting is not required in many other countries.  
* In Europe, Q fever often presents as [[hepatitis]] rather than [[pneumonia]] as it does in the United States.<ref name="pmid18931396">{{cite journal |vauthors=Delsing CE, Kullberg BJ |title=Q fever in the Netherlands: a concise overview and implications of the largest ongoing outbreak |journal=Neth J Med |volume=66 |issue=9 |pages=365–7 |year=2008 |pmid=18931396 |doi= |url=}}</ref>


Men are slightly more often affected than women, which most likely is attributed to different employment rates in typical professions.
===Developing Countries===
 
* [[Coxiella burnetii|''C. burnetii'']] is found everywhere except in Antarctica and New Zealand.  
"At risk" occupations include, but are not limited to:
* Q fever infections are often [[subclinical]].
* veterinary personnel
* stockyard workers
* farmers
* shearers
* animal transporters
* laboratory workers handling potentially infected veterinary samples or visiting abattoirs
* people who cull and process kangaroos
* hide (tannery) workers.


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
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Latest revision as of 23:55, 29 July 2020


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]

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Overview

Q fever is more prevalent in the elderly and in males. It has been a notifiable disease in the US since 1999. Q fever is underreported, thus scientists cannot reliably assess its incidence.[1]

Epidemiology and Demographics

Age

  • Q fever is slightly more prevalent in elderly people; however, it is often seen in various age groups.
  • Q fever is occasionally seen in children, especially those who live on a farm.
  • In infected children younger than 3 years old, Q fever usually presents as pneumonia.[2]

Gender

  • Due to differing employment rates in typical professions that predispose people to contracting Q fever, men are more often affected than women.[3]

Developed Countries

  • In 1999, Q fever became a notifiable disease in the United States but reporting is not required in many other countries.
  • In Europe, Q fever often presents as hepatitis rather than pneumonia as it does in the United States.[1]

Developing Countries

  • C. burnetii is found everywhere except in Antarctica and New Zealand.
  • Q fever infections are often subclinical.

References

  1. 1.0 1.1 Delsing CE, Kullberg BJ (2008). "Q fever in the Netherlands: a concise overview and implications of the largest ongoing outbreak". Neth J Med. 66 (9): 365–7. PMID 18931396.
  2. Hartzell JD, Wood-Morris RN, Martinez LJ, Trotta RF (2008). "Q fever: epidemiology, diagnosis, and treatment". Mayo Clin. Proc. 83 (5): 574–9. doi:10.4065/83.5.574. PMID 18452690.
  3. Maurin M, Raoult D (1999). "Q fever". Clin. Microbiol. Rev. 12 (4): 518–53. PMC 88923. PMID 10515901.


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