Pyelonephritis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

PMID: 21292654

Overview

The following are a few important aspects of the laboratory testing for pyelonephritis.[1]

  • Pyelonephritis can be diagnosed with the help or urinalysis and urine culture.
  • Cultures should always be obtained before administration of antibiotics if pyelonephritis is suspected.
  • A combination of leukocyte esterase test and nitrite test (with either of the two test being positive) is considered to be very effective with a sensitivity ranging from 75-84 and a specificity ranging from 82-98 percent.

Laboratory Findings

  • Urinalysis: Urinalysis is testing of a urine sample. The urine sample is collected in a special container in a health care provider’s office or commercial facility and can be tested in the same location or sent to a lab for analysis. The presence of white blood cells, nitrites and bacteria in the urine indicate infection and also indicate the need to start empirical treatment.
  • Urine culture: A urine culture is performed by placing part of a urine sample in a tube or dish with a substance that encourages any bacteria present to grow. The urine sample is collected in a special container in a health care provider’s office or commercial facility and sent to a lab for culture. Once the bacteria have multiplied, which usually takes 1 to 3 days, they can be identified. The health care provider can then determine the best treatment.

References

  1. Ramakrishnan K, Scheid DC (2005). "Diagnosis and management of acute pyelonephritis in adults". Am Fam Physician. 71 (5): 933–42. PMID 15768623.

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