Pulmonary hypertension laboratory tests: Difference between revisions
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==Overview== | ==Overview== | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
*Biochemistry,hematology and Thyroid function tests are required in all patients with pulmonary hypertension.(Important for diagnosis of chronic hemolytic anemia,myeloproliferative | *Biochemistry,hematology and Thyroid function tests are required in all patients with pulmonary hypertension.(Important for diagnosis of [[chronic hemolytic anemia]], [[myeloproliferative disorder]]s, thyroid disorders and [[chronic renal failure]] on [[dialysis]]). | ||
* Serologic testing to detect Connective tissue diseases(systemic sclerosis), HIV and Hepatitis. | * Serologic testing to detect Connective tissue diseases([[systemic sclerosis]]), [[HIV]] and [[Hepatitis]]. | ||
'''Systemic sclerosis''' is very important to exclude in pulmonary hypertension because this systemic disease has a very high prevalence of pulmonary arterial hypertension.Anti-Scl-70, anti-centromere,and U3-RNP are typically positive. | '''[[Systemic sclerosis]]''' is very important to exclude in pulmonary hypertension because this systemic disease has a very high prevalence of pulmonary arterial hypertension. [[Anti-Scl-70]], [[anti-centromere]], and [[U3-RNP]] are typically positive. | ||
*Liver function tests to exclude portal hypertension. | *Liver function tests to exclude [[portal hypertension]]. | ||
*Both ANP and BNP have been shown to correlate with the survival in Idiopathic Pulmonary Hypertension | *Both ANP and BNP have been shown to correlate with the survival in [[Idiopathic Pulmonary Hypertension]]. However NT-proBNP appears to be an independent predictor of survival and correlates with RV dysfunction. | ||
*Serum uric acid: reflects impaired oxidative metabolism of ischemic peripheral tissues.. | *Serum [[uric acid]]: reflects impaired [[oxidative]] metabolism of [[ischemic]] peripheral tissues.. | ||
==References== | ==References== | ||
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[[Category:Cardiology]] | |||
[[Category:Pulmonology]] | |||
[[Category:Disease]] | |||
[[Category:Mature chapter]] | |||
Revision as of 17:51, 25 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Assistant Editor(s)-in-Chief: Ralph Matar,
Overview
Laboratory Findings
- Biochemistry,hematology and Thyroid function tests are required in all patients with pulmonary hypertension.(Important for diagnosis of chronic hemolytic anemia, myeloproliferative disorders, thyroid disorders and chronic renal failure on dialysis).
- Serologic testing to detect Connective tissue diseases(systemic sclerosis), HIV and Hepatitis.
Systemic sclerosis is very important to exclude in pulmonary hypertension because this systemic disease has a very high prevalence of pulmonary arterial hypertension. Anti-Scl-70, anti-centromere, and U3-RNP are typically positive.
- Liver function tests to exclude portal hypertension.
- Both ANP and BNP have been shown to correlate with the survival in Idiopathic Pulmonary Hypertension. However NT-proBNP appears to be an independent predictor of survival and correlates with RV dysfunction.
- Serum uric acid: reflects impaired oxidative metabolism of ischemic peripheral tissues..