Pseudomyxoma peritonei history and symptoms: Difference between revisions
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Symptoms of pseudomyxoma peritonei include [[abdominal pain]], [[bloating]], [[abdominal distention]], weight changes, and [[infertility]]. | Symptoms of pseudomyxoma peritonei include [[abdominal pain]], [[bloating]], [[abdominal distention]], weight changes, and [[infertility]]. | ||
==History== | ==History== | ||
The median age of diagnosis for pseudomyxoma peritonei is 50 years | The median age of diagnosis for pseudomyxoma peritonei is 50 years of age. It is usually found incidentally in patients undergoing [[abdominal]] surgery or [[imaging]] for other medical conditions, most [[Patient|patients]] are diagnosed with advanced disease due to non specific symptoms of pseudomyxoma peritonei. The clinical presentation of the disease is dependent on the progression of the disease, [[tumor]]<nowiki/>s with [[Appendiceal cancers|appendiceal]] origin typically presents with [[appendicitis]]-like symptoms or if there is [[ovarian]] origin, it may present as a [[pelvic]] [[mass]] due to its compression impact on internal [[Organ (anatomy)|organs]]. More advanced disease may present with [[abdominal]] [[distension]], [[bowel obstruction]], and [[ascites]].<ref name="pmid17511043">{{cite journal |vauthors=Dixit A, Robertson JH, Mudan SS, Akle C |title=Appendiceal mucocoeles and pseudomyxoma peritonei |journal=World J. Gastroenterol. |volume=13 |issue=16 |pages=2381–4 |date=April 2007 |pmid=17511043 |pmc=4147153 |doi= |url=}}</ref><ref name="pmid11044169">{{cite journal |vauthors=Esquivel J, Sugarbaker PH |title=Clinical presentation of the Pseudomyxoma peritonei syndrome |journal=Br J Surg |volume=87 |issue=10 |pages=1414–8 |date=October 2000 |pmid=11044169 |doi=10.1046/j.1365-2168.2000.01553.x |url=}}</ref><ref name="pmid7750935">{{cite journal |vauthors=Ronnett BM, Kurman RJ, Zahn CM, Shmookler BM, Jablonski KA, Kass ME, Sugarbaker PH |title=Pseudomyxoma peritonei in women: a clinicopathologic analysis of 30 cases with emphasis on site of origin, prognosis, and relationship to ovarian mucinous tumors of low malignant potential |journal=Hum. Pathol. |volume=26 |issue=5 |pages=509–24 |date=May 1995 |pmid=7750935 |doi= |url=}}</ref> | ||
==Symptoms== | ==Symptoms== | ||
Symptoms of pseudomyxoma peritonei may include:<ref name="pmid11044169">{{cite journal |vauthors=Esquivel J, Sugarbaker PH |title=Clinical presentation of the Pseudomyxoma peritonei syndrome |journal=Br J Surg |volume=87 |issue=10 |pages=1414–8 |date=October 2000 |pmid=11044169 |doi=10.1046/j.1365-2168.2000.01553.x |url=}}</ref> | Symptoms of pseudomyxoma peritonei may include:<ref name="pmid11044169">{{cite journal |vauthors=Esquivel J, Sugarbaker PH |title=Clinical presentation of the Pseudomyxoma peritonei syndrome |journal=Br J Surg |volume=87 |issue=10 |pages=1414–8 |date=October 2000 |pmid=11044169 |doi=10.1046/j.1365-2168.2000.01553.x |url=}}</ref> | ||
* [[Abdominal]] or [[pelvic]] pain | * [[Abdominal]] or [[pelvic]] [[pain]] | ||
*New-onset [[hernia]]<ref name="pmid30026907">{{cite journal |vauthors=Gomes C, Tenreiro N, Marçal A, Moreira H, Pinto B, Avelar P |title=Pseudomyxoma peritonei presenting as irreducible epigastric hernia |journal=J Surg Case Rep |volume=2018 |issue=7 |pages=rjy148 |date=July 2018 |pmid=30026907 |pmc=6044295 |doi=10.1093/jscr/rjy148 |url=}}</ref> | *New-onset [[hernia]]<ref name="pmid30026907">{{cite journal |vauthors=Gomes C, Tenreiro N, Marçal A, Moreira H, Pinto B, Avelar P |title=Pseudomyxoma peritonei presenting as irreducible epigastric hernia |journal=J Surg Case Rep |volume=2018 |issue=7 |pages=rjy148 |date=July 2018 |pmid=30026907 |pmc=6044295 |doi=10.1093/jscr/rjy148 |url=}}</ref> | ||
* [[Bloating]] | * [[Bloating]] | ||
* [[Abdominal distension]] | * [[Abdominal distension]] | ||
* [[Weight change]] | * [[Weight change]] | ||
* Increased [[abdominal]] girth | * Increased [[abdominal]] girth | ||
*[[Appendicitis]]-like symptoms in some cases | *[[Appendicitis]]-like [[symptoms]] in some cases<ref name="pmid17343142">{{cite journal |vauthors=Smeenk RM, Verwaal VJ, Zoetmulder FA |title=[Pseudomyxoma peritonei; a rare tumour that can be treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy] |language=Dutch; Flemish |journal=Ned Tijdschr Geneeskd |volume=151 |issue=7 |pages=418–23 |date=February 2007 |pmid=17343142 |doi= |url=}}</ref> | ||
*[[Gynecological]] complaints in females such as [[menstrual]] irregularity due to the [[ovarian]] deposits of the mucinous tumor | *[[Gynecological]] complaints in [[Female|females]] such as [[menstrual]] irregularity due to the [[ovarian]] deposits of the [[mucinous]] [[tumor]] | ||
*[[Subcutaneous]] non tender [[umbilical]] | *[[Subcutaneous]] non tender [[umbilical]] [[Nodule (medicine)|nodules]] have also been reported in rare cases<ref name="pmid18224368">{{cite journal |vauthors=Srinivasaiah N, Retnasingam G, Kasarneni R, Slater B |title=Pseudomyxoma peritonei: a rare presentation as an umbilical nodule |journal=Ir J Med Sci |volume=178 |issue=2 |pages=219–21 |date=June 2009 |pmid=18224368 |doi=10.1007/s11845-008-0118-2 |url=}}</ref> | ||
== References == | == References == | ||
Latest revision as of 13:21, 2 April 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]Parminder Dhingra, M.D. [3]
Overview
Symptoms of pseudomyxoma peritonei include abdominal pain, bloating, abdominal distention, weight changes, and infertility.
History
The median age of diagnosis for pseudomyxoma peritonei is 50 years of age. It is usually found incidentally in patients undergoing abdominal surgery or imaging for other medical conditions, most patients are diagnosed with advanced disease due to non specific symptoms of pseudomyxoma peritonei. The clinical presentation of the disease is dependent on the progression of the disease, tumors with appendiceal origin typically presents with appendicitis-like symptoms or if there is ovarian origin, it may present as a pelvic mass due to its compression impact on internal organs. More advanced disease may present with abdominal distension, bowel obstruction, and ascites.[1][2][3]
Symptoms
Symptoms of pseudomyxoma peritonei may include:[2]
- Abdominal or pelvic pain
- New-onset hernia[4]
- Bloating
- Abdominal distension
- Weight change
- Increased abdominal girth
- Appendicitis-like symptoms in some cases[5]
- Gynecological complaints in females such as menstrual irregularity due to the ovarian deposits of the mucinous tumor
- Subcutaneous non tender umbilical nodules have also been reported in rare cases[6]
References
- ↑ Dixit A, Robertson JH, Mudan SS, Akle C (April 2007). "Appendiceal mucocoeles and pseudomyxoma peritonei". World J. Gastroenterol. 13 (16): 2381–4. PMC 4147153. PMID 17511043.
- ↑ 2.0 2.1 Esquivel J, Sugarbaker PH (October 2000). "Clinical presentation of the Pseudomyxoma peritonei syndrome". Br J Surg. 87 (10): 1414–8. doi:10.1046/j.1365-2168.2000.01553.x. PMID 11044169.
- ↑ Ronnett BM, Kurman RJ, Zahn CM, Shmookler BM, Jablonski KA, Kass ME, Sugarbaker PH (May 1995). "Pseudomyxoma peritonei in women: a clinicopathologic analysis of 30 cases with emphasis on site of origin, prognosis, and relationship to ovarian mucinous tumors of low malignant potential". Hum. Pathol. 26 (5): 509–24. PMID 7750935.
- ↑ Gomes C, Tenreiro N, Marçal A, Moreira H, Pinto B, Avelar P (July 2018). "Pseudomyxoma peritonei presenting as irreducible epigastric hernia". J Surg Case Rep. 2018 (7): rjy148. doi:10.1093/jscr/rjy148. PMC 6044295. PMID 30026907.
- ↑ Smeenk RM, Verwaal VJ, Zoetmulder FA (February 2007). "[Pseudomyxoma peritonei; a rare tumour that can be treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy]". Ned Tijdschr Geneeskd (in Dutch; Flemish). 151 (7): 418–23. PMID 17343142.
- ↑ Srinivasaiah N, Retnasingam G, Kasarneni R, Slater B (June 2009). "Pseudomyxoma peritonei: a rare presentation as an umbilical nodule". Ir J Med Sci. 178 (2): 219–21. doi:10.1007/s11845-008-0118-2. PMID 18224368.