Primary hyperaldosteronism causes: Difference between revisions
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==Causes== | ==Causes== | ||
=== Common Causes === | === Common Causes === | ||
Common causes of Conn's Syndrome may be divided into: | |||
*Adrenal causes: | *Adrenal causes: | ||
**Aldosterone-secreting adrenal adenoma (APA-benign tumor, 50-60%) | **Aldosterone-secreting adrenal adenoma (APA-benign tumor, 50-60%) | ||
Revision as of 17:06, 7 July 2017
Template:Conn syndrome Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]
Overview
Causes
Common Causes
Common causes of Conn's Syndrome may be divided into:
- Adrenal causes:
- Aldosterone-secreting adrenal adenoma (APA-benign tumor, 50-60%)
- Idiopathic hyperaldosteronism (IHA-Bilateral hyperplasia of the adrenal gland, 40-50%)
- Extra-adrenal causes
- Ectopic secretion of aldosterone (Ovaries and Kidneys)
Less Common Causes
- Familial hyperaldosteronism type I (glucocorticoid-remediable aldosteronism [GRA])
- Familial hyperaldosteronism II (the familial occurrence of APA or bilateral idiopathic hyperplasia or both)
- Familial hyperaldosteronism type III (associated with the germline mutation in the KCNJ5 potassium channel)
- Pure aldosterone-producing adrenocortical carcinomas
- Unilateral adrenal hyperplasia