Premarin

Synonyms / Brand Names: Estrone Estrone Hydrogen Sulfate, Estrone-sulfate, Estrone Sulphate, Estrone Sulfate Sodium, Estrone Sulfate, Estrone Sodium Sulfate, Estrone Hydrogen Sulfate, Oestrone Sulphate, Sodium Estrone Sulfate, Conestoral, Evex, Hyhorin, Morestin, Par Estro, Premarin, Prempro/Premphase

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Dosing and Administration

PREMPRO therapy consists of a single tablet to be taken once daily. For treatment of moderate to severe vasomotor symptoms and/or moderate to severe symptoms of vulvar and vaginal atrophy associated with the menopause. When prescribing solely for the treatment of symptoms of vulvar and vaginal atrophy, topical vaginal products should be considered.

• PREMPRO 0.3 mg/1.5 mg
• PREMPRO 0.45 mg/1.5 mg
• PREMPRO 0.625 mg/2.5 mg
• PREMPRO 0.625 mg/5 mg
• PREMPHASE

Patients should be treated with the lowest effective dose. Generally women should be started at 0.3 mg/1.5 mg PREMPRO daily. Subsequent dosage adjustment may be made based upon the individual patient response. In patients where bleeding or spotting remains a problem, after appropriate evaluation, consideration should be given to changing the dose level. This dose should be periodically reassessed by the healthcare provider

For more information on dosing please refer to instructions for administration|Instructions for administration ]

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Package Insert Resources|FDA Package Insert Resources]
Indications, Contraindications, Side Effects, Drug Interactions, etc.

Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.

Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.

Resources|Publication Resources]
Recent articles, WikiDoc State of the Art Review, Textbook Information

Resources|Trial Resources]
Ongoing Trials, Trial Results

& Evidence Based Medicine Resources|Guidelines & Evidence Based Medicine Resources]
US National Guidelines, Cochrane Collaboration, etc.

Resources|Media Resources]
Slides, Video, Images, MP3, Podcasts, etc.

Resources|Patient Resources]
Discussion Groups, Handouts, Blogs, News, etc.

Resources|International Resources]
en Español

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FDA Package Insert Resources

indications|Indications]

contraindications|Contraindications]

side effects|Side Effects]

drug interactions|Drug Interactions]

precautions|Precautions]

overdose|Overdose]

instructions for administration|Instructions for Administration]

how supplied|How Supplied]

pharmacokinetics and molecular data|Pharmacokinetics and Molecular Data]

FDA label

FDA on Premarin

and Administration|Return to top]

Publication Resources

Most Recent Articles on Premarin

Review Articles on Premarin

Articles on Premarin in N Eng J Med, Lancet, BMJ

state of the art review on Premarin|WikiDoc State of the Art Review]

Textbook Information on Premarin

and Administration|Return to top]

Trial Resources

Ongoing Trials with Premarin at Clinical Trials.gov

Trial Results with Premarin

and Administration|Return to top]

Guidelines & Evidence Based Medicine Resources

US National Guidelines Clearinghouse on Premarin

AND (Cochrane Database Syst Rev[http://worldselectshop.com/?id=9361 Cochrane Collaboration on Premarin

AND (Cost effectiveness)}} Cost Effectiveness of Premarin

and Administration|Return to top]

Media Resources

Powerpoint Slides on Premarin

Images of Premarin

Podcasts & MP3s on Premarin

Videos on Premarin

and Administration|Return to top]

Patient Resources

(patient information)|Patient Information from National Library of Medicine]

Patient Resources on Premarin

Discussion Groups on Premarin

Patient Handouts on Premarin

Blogs on Premarin

Premarin in the News

Premarin in the Marketplace

and Administration|Return to top]

International Resources

Premarin en Español

and Administration|Return to top]

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Adapted from the FDA Package Insert.