Potassium bicarbonate: Difference between revisions

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{{Chembox new
{{DrugProjectFormSinglePage
|   Name = Potassium bicarbonate
|aOrAn=a
|   ImageFile = Potassium bicarbonate.jpg
|indicationType=treatment
|   ImageSize = 200px
|hasBlackBoxWarning=Yes
|   ImageName = Potassium bicarbonate
|adverseReactions=<!--Black Box Warning-->
|   IUPACName = potassium hydrogen carbonate<!-- e.g. Iron(II) chloride -->
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
|   OtherNames = potassium acid carbonate<!-- e.g. Ferrous chloride etc, + linked mineral names -->
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>
| Section1 = {{Chembox Identifiers
 
|   CASNo = 298-14-6
* Content
  }}
 
| Section2 = {{Chembox Properties
<!--Adult Indications and Dosage-->
|   Formula = KHCO<sub>3</sub>
 
|   MolarMass = 100.11 g/mol
<!--FDA-Labeled Indications and Dosage (Adult)-->
|   Appearance = colorless crystals or white powder
|fdaLIADAdult======Condition1=====
|   Density = 2.17 g/cm<sup>3</sup>, solid
 
|   Solubility = 32.2 g/100 ml (20°C)
* Dosing Information
|   MeltingPt = decomposes 100°C-200°C
 
  }}
:* Dosage
| Section3 = {{Chembox Structure
 
|   CrystalStruct = [[monoclinic]]<!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention "close packed" or similar. You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl<sub>2</sub>]]  -->
=====Condition2=====
  }}
 
| Section7 = {{Chembox Hazards
* Dosing Information
|   ExternalMSDS = [http://msds.ehs.cornell.edu/msds/msdsdod/a495/m247034.htm Potassium bicarbonate]
 
  }}
:* Dosage
| Section8 = {{Chembox Related
 
|   OtherCpds = [[potassium carbonate]]
=====Condition3=====
  }}
 
* Dosing Information
 
:* Dosage
 
=====Condition4=====
 
* Dosing Information
 
:* Dosage
 
<!--Off-Label Use and Dosage (Adult)-->
 
<!--Guideline-Supported Use (Adult)-->
|offLabelAdultGuideSupport======Condition1=====
 
* Developed by:
 
* Class of Recommendation:
 
* Strength of Evidence:
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
 
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* Dosing Information
 
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<!--Pediatric Indications and Dosage-->
 
<!--FDA-Labeled Indications and Dosage (Pediatric)-->
|fdaLIADPed======Condition1=====
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients.
 
<!--Off-Label Use and Dosage (Pediatric)-->
 
<!--Guideline-Supported Use (Pediatric)-->
|offLabelPedGuideSupport======Condition1=====
 
* Developed by:
 
* Class of Recommendation:
 
* Strength of Evidence:
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
 
<!--Non–Guideline-Supported Use (Pediatric)-->
|offLabelPedNoGuideSupport======Condition1=====
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
 
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|contraindications=* Condition1
 
<!--Warnings-->
|warnings=* Description
 
====Precautions====
 
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=====Endocrine=====
 
 
 
 
=====Hematologic and Lymphatic=====
 
 
 
 
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=====Musculoskeletal=====
 
 
 
 
=====Neurologic=====
 
 
 
 
=====Respiratory=====
 
 
 
 
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=====Special Senses=====
 
 
 
 
=====Urogenital=====
 
 
 
 
=====Miscellaneous=====
 
 
 
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|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.
 
=====Body as a Whole=====
 
 
 
=====Cardiovascular=====
 
 
 
=====Digestive=====
 
 
 
=====Endocrine=====
 
 
 
=====Hematologic and Lymphatic=====
 
 
 
=====Metabolic and Nutritional=====
 
 
 
=====Musculoskeletal=====
 
 
 
=====Neurologic=====
 
 
 
=====Respiratory=====
 
 
 
=====Skin and Hypersensitivy Reactions=====
 
 
 
=====Special Senses=====
 
 
 
=====Urogenital=====
 
 
 
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|useInNursing=There is no FDA guidance on the use of {{PAGENAME}} with respect to nursing mothers.
|useInPed=There is no FDA guidance on the use of {{PAGENAME}} with respect to pediatric patients.
|useInGeri=There is no FDA guidance on the use of {{PAGENAME}} with respect to geriatric patients.
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|useInRace=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific racial populations.
|useInRenalImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with renal impairment.
|useInHepaticImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with hepatic impairment.
|useInReproPotential=There is no FDA guidance on the use of {{PAGENAME}} in women of reproductive potentials and males.
|useInImmunocomp=There is no FDA guidance one the use of {{PAGENAME}} in patients who are immunocompromised.
 
<!--Administration and Monitoring-->
|administration=* Oral
 
* Intravenous
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.
 
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====Signs and Symptoms====
 
* Description
 
====Management====
 
* Description
 
===Chronic Overdose===
 
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: [[File:{{PAGENAME}}01.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
 
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==Overview==
{{LabelImage
'''Potassium bicarbonate''' (also known as '''potassium hydrogen carbonate''' or '''potassium acid carbonate'''), is a colorless, odorless, slightly [[Base (chemistry)|basic]], salty substance. The compound is used as a source of [[carbon dioxide]] for leavening in baking, extinguishing fire in powder fire extinguishers, acting as a [[reagent]], and a strong [[buffering agent]] in medications. The US [[Food and Drug Administration]] (FDA) recognizes potassium bicarbonate as "[[generally recognized as safe]]".  It is used as a base in foods to regulate pH.
|fileName={{PAGENAME}}11.png
}}
{{LabelImage
|fileName={{PAGENAME}}11.png
}}
<!--Pill Image-->


Potassium bicarbonate is [[soluble]] in [[water]], and is often found added to bottled water to affect [[taste]]; however, it is not soluble in [[alcohol]]. Decomposition of the substance occurs between 100°[[Celsius|C]] and 120°C into [[Potassium|K]]<sub>2</sub>[[Carbon|C]][[Oxygen|O]]<sub>3</sub> ([[potassium carbonate]]), [[Hydrogen|H]]<sub>2</sub>[[Oxygen|O]] ([[water]]), and [[Carbon|C]][[Oxygen|O]]<sub>2</sub> ([[carbon dioxide]]). In [[concentration]]s greater than 0.5%, KHCO<sub>3</sub> can have phytotoxic effects on plants (potassium bicarbonate has widespread use in crops, especially for neutralizing [[acid]]ic soil), although there is no evidence of human [[carcinogenicity]], no adverse effects of overexposure, and no [[LD50|LD<sub>50</sub>]].


Physically, potassium bicarbonate occurs as a crystal or a soft white granular powder. It has a [[CAS registry number|CAS No]] [298-14-6]. It is manufactured by reacting [[potassium carbonate]] with [[carbon dioxide]] and [[water]]:


:[[Potassium|K]]<sub>2</sub>[[Carbon|C]][[Oxygen|O]]<sub>3</sub> + [[Carbon|C]][[Oxygen|O]]<sub>2</sub> + [[Hydrogen|H]]<sub>2</sub>[[Oxygen|O]] &rarr; 2 [[Potassium|K]][[Hydrogen|H]][[Carbon|C]][[Oxygen|O]]<sub>3</sub>
<!--Label Display Image-->


Potassium bicarbonate is used as a fire suppression agent ("BC powder") in some dry powder fire extinguishers, as the principal component of the Purple-K powder. It is the only dry chemical fire suppression agent recognized by the [[National Fire Protection Association]] for firefighting at airport crash rescue sites. It is about twice as effective in fire suppression as [[sodium bicarbonate]]. [http://www.nrl.navy.mil/content.php?P=PURPLEK]


==External links==


* [http://www.armandproducts.com/pdfs/PotBiVs6.PDF Potassium Bicarbonate Handbook]
* [http://www.omri.org/Potassium_bicarbonate_crops.pdf Potassium Bicarbonate: Crops]


{{Mineral supplements}}
{{SIB}}
[[Category:Potassium compounds]]
[[Category:Bicarbonates]]
[[Category:Acid salts]]
[[Category:Endocrinology]]


[[de:Kaliumhydrogencarbonat]]
<!--Category-->
[[ja:炭酸水素カリウム]]
[[pt:Bicarbonato de potássio]]


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Revision as of 17:54, 22 April 2015

Potassium bicarbonate
Black Box Warning
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];

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Black Box Warning

ConditionName:
See full prescribing information for complete Boxed Warning.
ConditionName:
  • Content

Overview

Potassium bicarbonate is a {{{drugClass}}} that is FDA approved for the treatment of {{{indication}}}. There is a Black Box Warning for this drug as shown here. Common adverse reactions include .

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

Condition1
  • Dosing Information
  • Dosage
Condition2
  • Dosing Information
  • Dosage
Condition3
  • Dosing Information
  • Dosage
Condition4
  • Dosing Information
  • Dosage

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

Condition1
  • Developed by:
  • Class of Recommendation:
  • Strength of Evidence:
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Guideline-Supported Use of Potassium bicarbonate in adult patients.

Non–Guideline-Supported Use

Condition1
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Non–Guideline-Supported Use of Potassium bicarbonate in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

Condition1
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding FDA-Labeled Use of Potassium bicarbonate in pediatric patients.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

Condition1
  • Developed by:
  • Class of Recommendation:
  • Strength of Evidence:
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Guideline-Supported Use of Potassium bicarbonate in pediatric patients.

Non–Guideline-Supported Use

Condition1
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Non–Guideline-Supported Use of Potassium bicarbonate in pediatric patients.

Contraindications

  • Condition1

Warnings

ConditionName:
See full prescribing information for complete Boxed Warning.
ConditionName:
  • Content
  • Description

Precautions

  • Description

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Potassium bicarbonate in the drug label.

Body as a Whole
Cardiovascular
Digestive
Endocrine
Hematologic and Lymphatic
Metabolic and Nutritional
Musculoskeletal
Neurologic
Respiratory
Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous

Postmarketing Experience

There is limited information regarding Postmarketing Experience of Potassium bicarbonate in the drug label.

Body as a Whole
Cardiovascular
Digestive
Endocrine
Hematologic and Lymphatic
Metabolic and Nutritional
Musculoskeletal
Neurologic
Respiratory
Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous

Drug Interactions

  • Drug
  • Description

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA):

  • Pregnancy Category


Pregnancy Category (AUS):

  • Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Potassium bicarbonate in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Potassium bicarbonate during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Potassium bicarbonate with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Potassium bicarbonate with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Potassium bicarbonate with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Potassium bicarbonate with respect to specific gender populations.

Race

There is no FDA guidance on the use of Potassium bicarbonate with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Potassium bicarbonate in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Potassium bicarbonate in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Potassium bicarbonate in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Potassium bicarbonate in patients who are immunocompromised.

Administration and Monitoring

Administration

  • Oral
  • Intravenous

Monitoring

There is limited information regarding Monitoring of Potassium bicarbonate in the drug label.

  • Description

IV Compatibility

There is limited information regarding IV Compatibility of Potassium bicarbonate in the drug label.

Overdosage

Acute Overdose

Signs and Symptoms

  • Description

Management

  • Description

Chronic Overdose

There is limited information regarding Chronic Overdose of Potassium bicarbonate in the drug label.

Pharmacology

There is limited information regarding Potassium bicarbonate Pharmacology in the drug label.

Mechanism of Action

Structure

File:Potassium bicarbonate01.png
This image is provided by the National Library of Medicine.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Potassium bicarbonate in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Potassium bicarbonate in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Potassium bicarbonate in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Potassium bicarbonate in the drug label.

How Supplied

Storage

There is limited information regarding Potassium bicarbonate Storage in the drug label.

Images

Drug Images

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Package and Label Display Panel

{{#ask: Label Page::Potassium bicarbonate |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Patient Counseling Information of Potassium bicarbonate in the drug label.

Precautions with Alcohol

  • Alcohol-Potassium bicarbonate interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

Look-Alike Drug Names

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. ↑ Empty citation (help)
  2. ↑ "http://www.ismp.org". External link in |title= (help)

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