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* There is an association between PMR and [[giant cell arteritis]].  While 40 to 60% of patients with [[giant cell arteritis]] have PMR, 16 to 21% of patients with PMR develop [[giant cell arteritis]].<ref name="pmid7598301">{{cite journal| author=Salvarani C, Gabriel SE, O'Fallon WM, Hunder GG| title=The incidence of giant cell arteritis in Olmsted County, Minnesota: apparent fluctuations in a cyclic pattern. | journal=Ann Intern Med | year= 1995 | volume= 123 | issue= 3 | pages= 192-4 | pmid=7598301 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7598301  }} </ref><ref name="pmid7880191">{{cite journal| author=Salvarani C, Gabriel SE, O'Fallon WM, Hunder GG| title=Epidemiology of polymyalgia rheumatica in Olmsted County, Minnesota, 1970-1991. | journal=Arthritis Rheum | year= 1995 | volume= 38 | issue= 3 | pages= 369-73 | pmid=7880191 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7880191  }} </ref><ref name="pmid1629827">{{cite journal| author=Franzén P, Sutinen S, von Knorring J| title=Giant cell arteritis and polymyalgia rheumatica in a region of Finland: an epidemiologic, clinical and pathologic study, 1984-1988. | journal=J Rheumatol | year= 1992 | volume= 19 | issue= 2 | pages= 273-6 | pmid=1629827 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1629827  }} </ref>  Some symptoms of [[temporal arteritis]] include severe [[headaches]], scalp tenderness, [[jaw claudication]], [[fever]], distorted vision or aching in the limbs caused by decreased blood flow, and [[fatigue]].
* There is an association between PMR and [[giant cell arteritis]].  While 40 to 60% of patients with [[giant cell arteritis]] have PMR, 16 to 21% of patients with PMR develop [[giant cell arteritis]].<ref name="pmid7598301">{{cite journal| author=Salvarani C, Gabriel SE, O'Fallon WM, Hunder GG| title=The incidence of giant cell arteritis in Olmsted County, Minnesota: apparent fluctuations in a cyclic pattern. | journal=Ann Intern Med | year= 1995 | volume= 123 | issue= 3 | pages= 192-4 | pmid=7598301 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7598301  }} </ref><ref name="pmid7880191">{{cite journal| author=Salvarani C, Gabriel SE, O'Fallon WM, Hunder GG| title=Epidemiology of polymyalgia rheumatica in Olmsted County, Minnesota, 1970-1991. | journal=Arthritis Rheum | year= 1995 | volume= 38 | issue= 3 | pages= 369-73 | pmid=7880191 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7880191  }} </ref><ref name="pmid1629827">{{cite journal| author=Franzén P, Sutinen S, von Knorring J| title=Giant cell arteritis and polymyalgia rheumatica in a region of Finland: an epidemiologic, clinical and pathologic study, 1984-1988. | journal=J Rheumatol | year= 1992 | volume= 19 | issue= 2 | pages= 273-6 | pmid=1629827 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1629827  }} </ref>  Some symptoms of [[temporal arteritis]] include severe [[headaches]], scalp tenderness, [[jaw claudication]], [[fever]], distorted vision or aching in the limbs caused by decreased blood flow, and [[fatigue]].


==References==
==References==

Revision as of 21:37, 1 June 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Polymyalgia rheumatica (PMR) is typically characterized by symmetrical pain and morning stiffness in the proximal joints and limbs, including the neck, the shoulder girdle, the pelvic girdle, the lower back, and the thighs. In some patients, there is involvement of the distal parts of the body such as peripheral synovitis or arthritis. Constitutional symptoms can also be present, and they include fever, fatigue, loss of appetite, and weight loss.[1] There is an association between PMR and giant cell arteritis which can present with one or more of the following symptoms headaches, scalp tenderness, jaw claudication, fever, or distorted vision.[2][3][4]

History and Symptoms

  • PMR is typically characterized by pain and morning stiffness in the proximal joints and limbs, including the neck, the shoulder girdle, the pelvic girdle, the lower back, and the thighs.[1] The symptoms last for more than 30 days and involve the body parts symmetrically.[5] The morning stiffness lasts for at approximately 30-45 minutes. The pain is moderate to severe, and may inhibit the activity of the person. These symptoms usually occur in the morning, or after sleeping. The muscle strength is intact, though it may be limited by pain. The symptoms can interfere with sleep and daily activities such as getting dressed in the morning or getting up from a chair.

References

  1. 1.0 1.1 1.2 1.3 Dasgupta B, Cimmino MA, Maradit-Kremers H, Schmidt WA, Schirmer M, Salvarani C; et al. (2012). "2012 provisional classification criteria for polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative". Ann Rheum Dis. 71 (4): 484–92. doi:10.1136/annrheumdis-2011-200329. PMC 3298664. PMID 22388996.
  2. 2.0 2.1 Salvarani C, Gabriel SE, O'Fallon WM, Hunder GG (1995). "The incidence of giant cell arteritis in Olmsted County, Minnesota: apparent fluctuations in a cyclic pattern". Ann Intern Med. 123 (3): 192–4. PMID 7598301.
  3. 3.0 3.1 Salvarani C, Gabriel SE, O'Fallon WM, Hunder GG (1995). "Epidemiology of polymyalgia rheumatica in Olmsted County, Minnesota, 1970-1991". Arthritis Rheum. 38 (3): 369–73. PMID 7880191.
  4. 4.0 4.1 Franzén P, Sutinen S, von Knorring J (1992). "Giant cell arteritis and polymyalgia rheumatica in a region of Finland: an epidemiologic, clinical and pathologic study, 1984-1988". J Rheumatol. 19 (2): 273–6. PMID 1629827.
  5. Salvarani C, Cantini F, Boiardi L, Hunder GG (2002). "Polymyalgia rheumatica and giant-cell arteritis". N Engl J Med. 347 (4): 261–71. doi:10.1056/NEJMra011913. PMID 12140303.

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