Phosphate nephropathy: Difference between revisions

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===Gender===
===Gender===
Several studies report, the majority of cases of acute phosphate nephropathy in the female gender. It could be related to their smaller heights and subsequently less GFR as compared to men. <ref name="pmidPMID: 19675530" />  
Several studies report, the majority of cases of acute phosphate nephropathy in the female gender. It could be related to their smaller heights and subsequently less GFR as compared to men. <ref name="pmidPMID: 19675530" /> <ref name="pmid16192415">{{cite journal| author=Markowitz GS, Stokes MB, Radhakrishnan J, D'Agati VD| title=Acute phosphate nephropathy following oral sodium phosphate bowel purgative: an underrecognized cause of chronic renal failure. | journal=J Am Soc Nephrol | year= 2005 | volume= 16 | issue= 11 | pages= 3389-96 | pmid=16192415 | doi=10.1681/ASN.2005050496 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16192415  }} </ref>


===Age===
===Age===

Revision as of 15:15, 10 June 2020

Phosphate nephropathy Microchapters

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Overview

Pathophysiology

Causes

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

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Diagnostic Criteria

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Physical Examination

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Biopsy

X Ray

Ultrasound

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ayesha Javid, MBBS[2]

Overview

Acute phosphate nephropathy is a form of renal injury that occurs as a result of consumption of bowel purgatives which contain oral sodium phosphate (OSP). It can lead to acute kidney injury followed by chronic renal failure.[1] OSP is a commonly used purgative especially before colonoscopy.

Pathophysiology

Causes

Epidemiology and Demographics

Gender

Several studies report, the majority of cases of acute phosphate nephropathy in the female gender. It could be related to their smaller heights and subsequently less GFR as compared to men. [1] [2]

Age

Several epidemiological studies have identified advanced age as an independent risk factor of acute phosphate nephropathy. However, the exact age at which the patient's predisposition increase has not been identified yet. [1]

Risk Factors

Advanced age

Chronic Kidney disease

Hypertension

Drugs

Diabates mellitus

Female gender

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria | History and Symptoms | Physical Examination | Laboratory Findings | Phosphate Nephropathy Biopsy | X ray | Ultrasound | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

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  1. 1.0 1.1 1.2 Markowitz GS, Perazella MA (2009). "Acute phosphate nephropathy". Kidney Int. 76 (10): 1027–34. doi:10.1038/ki.2009.308. PMID 19675530 PMID: 19675530 Check |pmid= value (help).
  2. Markowitz GS, Stokes MB, Radhakrishnan J, D'Agati VD (2005). "Acute phosphate nephropathy following oral sodium phosphate bowel purgative: an underrecognized cause of chronic renal failure". J Am Soc Nephrol. 16 (11): 3389–96. doi:10.1681/ASN.2005050496. PMID 16192415.