Phenformin

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Phenformin
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Clinical data
ATC code
Identifiers
CAS Number
PubChem CID
DrugBank
E number{{#property:P628}}
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Chemical and physical data
FormulaC10H15N5
Molar mass205.26 g/mol

Phenformin is an anti-diabetic drug from the biguanide class. It is no longer widely available because it is known to induce lactic acidosis.[1]

Like metformin, phenformin leads to weight loss, something often desirable in type 2 diabetics, and it is for this reason that there is still some interest in it.[2]

References

  1. Enia G, Garozzo M, Zoccali C (1997). "Lactic acidosis induced by phenformin is still a public health problem in Italy". BMJ. 315 (7120): 1466–7. PMID 9418116.
  2. Rosand J, Friedberg J, Yang J (1997). "Fatal phenformin-associated lactic acidosis". Ann Intern Med. 127 (2): 170. PMID 9230023.

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