Peutz-Jeghers syndrome history and symptoms: Difference between revisions
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The hallmark of Peutz-Jeghers syndrome is hamatomatous [[Polyp|polyps]]. A positive history of mucucutaneous [[hyperpigmentation]] and [[rectal bleeding]] is suggestive of Peutz-Jeghers syndrome. The most common symptoms of Peutz-Jeghers syndrome include [[abdominal pain]], [[fatigue]], and [[weight loss]]. | The hallmark of Peutz-Jeghers syndrome is hamatomatous [[Polyp|polyps]]. A positive history of mucucutaneous [[hyperpigmentation]] and [[rectal bleeding]] is suggestive of Peutz-Jeghers syndrome. The most common symptoms of Peutz-Jeghers syndrome include [[abdominal pain]], [[fatigue]], and [[weight loss]]. | ||
==History and Symptoms== | ==History and Symptoms== | ||
Individuals with Peutz-Jeghers syndrome may have positive history of:<ref name="KopacovaTacheci2009">{{cite journal|last1=Kopacova|first1=Marcela|last2=Tacheci|first2=Ilja|last3=Rejchrt|first3=Stanislav|last4=Bures|first4=Jan|title=Peutz-Jeghers syndrome: Diagnostic and therapeuticapproach|journal=World Journal of Gastroenterology|volume=15|issue=43|year=2009|pages=5397|issn=1007-9327|doi=10.3748/wjg.15.5397}}</ref> | |||
* Peutz-Jeghers syndrome in family | |||
* Mucucutaneous [[hyperpigmentation]] of the [[oral mucosa]] | * Mucucutaneous [[hyperpigmentation]] of the [[oral mucosa]] | ||
* [[Rectal bleeding|Rectal bleeds]] | * [[Rectal bleeding|Rectal bleeds]] | ||
| Line 23: | Line 24: | ||
*[[Hematemesis]] | *[[Hematemesis]] | ||
*[[Fatigue]] | *[[Fatigue]] | ||
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{| | {| | ||
! colspan="2" style="background:#4479BA; color: #FFFFFF;" align="center" + |Percentage of symptom occurrence in Peutz-Jeghers syndrome | ! colspan="2" style="background:#4479BA; color: #FFFFFF;" align="center" + |Percentage of symptom occurrence in Peutz-Jeghers syndrome | ||
Latest revision as of 16:50, 21 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]
Overview
The hallmark of Peutz-Jeghers syndrome is hamatomatous polyps. A positive history of mucucutaneous hyperpigmentation and rectal bleeding is suggestive of Peutz-Jeghers syndrome. The most common symptoms of Peutz-Jeghers syndrome include abdominal pain, fatigue, and weight loss.
History and Symptoms
Individuals with Peutz-Jeghers syndrome may have positive history of:[1]
- Peutz-Jeghers syndrome in family
- Mucucutaneous hyperpigmentation of the oral mucosa
- Rectal bleeds
- Abdominal pain
- Fatigue
Symptoms of Peutz-Jeghers syndrome include the following:[1][2][3]
- Mucocutaneous hyperpigmentation (mouth, hands, and feet)
- Rectal bleeding
- Melena
- Rectal prolapse
- Abdominal pain
- Weight loss
- Gynecomastia in males
- Menstrual irregularities in females
- Hematemesis
- Fatigue
| Percentage of symptom occurrence in Peutz-Jeghers syndrome | |
|---|---|
| Symptoms | Percentage (%) |
| Abnormal Pigmentation | 80 to 90 |
| GI Bleeding | 30 to 79 |
| Abdominal Pain | 5 to 29 |
References
- ↑ 1.0 1.1 Kopacova, Marcela; Tacheci, Ilja; Rejchrt, Stanislav; Bures, Jan (2009). "Peutz-Jeghers syndrome: Diagnostic and therapeuticapproach". World Journal of Gastroenterology. 15 (43): 5397. doi:10.3748/wjg.15.5397. ISSN 1007-9327.
- ↑ Giardiello, F; Trimbath, J (2006). "Peutz-Jeghers Syndrome and Management Recommendations". Clinical Gastroenterology and Hepatology. 4 (4): 408–415. doi:10.1016/j.cgh.2005.11.005. ISSN 1542-3565.
- ↑ "Peutz-Jeghers syndrome | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program".