Peutz-Jeghers syndrome history and symptoms: Difference between revisions
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*[[Hematemesis]] | *[[Hematemesis]] | ||
*[[Fatigue]] | *[[Fatigue]] | ||
{| | {| | ||
| | ! colspan="2" style="background:#4479BA; color: #FFFFFF;" align="center" + |Percentage of symptom occurrence in Peutz-Jeghers syndrome | ||
!Symptoms | ! style="background:#7d7d7d; color: #FFFFFF;" align="center" + |Symptoms | ||
!Percentage (%) | ! style="background:#7d7d7d; color: #FFFFFF;" align="center" + |Percentage (%) | ||
|- | |- | ||
|Abnormal Pigmentation | | style="background:#DCDCDC;" align="center" + |Abnormal Pigmentation | ||
|80 to 90 | | style="background:#F5F5F5;" align="center" + |80 to 90 | ||
|- | |- | ||
|GI Bleeding | | style="background:#DCDCDC;" align="center" + |GI Bleeding | ||
|30 to 79 | | style="background:#F5F5F5;" align="center" + |30 to 79 | ||
|- | |- | ||
|Abdominal Pain | | style="background:#DCDCDC;" align="center" + |Abdominal Pain | ||
|5 to 29 | | style="background:#F5F5F5;" align="center" + |5 to 29 | ||
|} | |} | ||
Revision as of 20:10, 20 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]
Overview
The hallmark of Peutz-Jeghers syndrome is hamatomatous polyps. A positive history of mucucutaneous hyperpigmentation and rectal bleeding is suggestive of Peutz-Jeghers syndrome. The most common symptoms of Peutz-Jeghers syndrome include abdominal pain, fatigue, and weight loss.
History and Symptoms
Symptoms of Peutz-Jeghers syndrome include the following:[1][2][3]
- Mucocutaneous hyperpigmentation (mouth, hands, and feet)
- Rectal bleeding
- Melena
- Rectal prolapse
- Abdominal pain
- Weight loss
- Gynecomastia in males
- Menstrual irregularities in females
- Hematemesis
- Fatigue
Percentage of symptom occurrence in Peutz-Jeghers syndrome | Symptoms | Percentage (%) | |
---|---|---|---|
Abnormal Pigmentation | 80 to 90 | ||
GI Bleeding | 30 to 79 | ||
Abdominal Pain | 5 to 29 |
References
- ↑ Giardiello, F; Trimbath, J (2006). "Peutz-Jeghers Syndrome and Management Recommendations". Clinical Gastroenterology and Hepatology. 4 (4): 408–415. doi:10.1016/j.cgh.2005.11.005. ISSN 1542-3565.
- ↑ Kopacova, Marcela; Tacheci, Ilja; Rejchrt, Stanislav; Bures, Jan (2009). "Peutz-Jeghers syndrome: Diagnostic and therapeuticapproach". World Journal of Gastroenterology. 15 (43): 5397. doi:10.3748/wjg.15.5397. ISSN 1007-9327.
- ↑ "Peutz-Jeghers syndrome | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program".