Pancreatic cancer MRI: Difference between revisions

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==MRI==
==MRI==
'''MRI:''' <ref name="pmid22811847">{{cite journal| author=Tummala P, Junaidi O, Agarwal B| title=Imaging of pancreatic cancer: An overview. | journal=J Gastrointest Oncol | year= 2011 | volume= 2 | issue= 3 | pages= 168-74 | pmid=22811847 | doi=10.3978/j.issn.2078-6891.2011.036 | pmc=3397617 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22811847  }} </ref> <ref name="pmid24976723">{{cite journal| author=Lee ES, Lee JM| title=Imaging diagnosis of pancreatic cancer: a state-of-the-art review. | journal=World J Gastroenterol | year= 2014 | volume= 20 | issue= 24 | pages= 7864-77 | pmid=24976723 | doi=10.3748/wjg.v20.i24.7864 | pmc=4069314 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24976723  }} </ref><ref name="pmid22786999">{{cite journal| author=Sahani DV, Bonaffini PA, Catalano OA, Guimaraes AR, Blake MA| title=State-of-the-art PET/CT of the pancreas: current role and emerging indications. | journal=Radiographics | year= 2012 | volume= 32 | issue= 4 | pages= 1133-58; discussion 1158-60 | pmid=22786999 | doi=10.1148/rg.324115143 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22786999  }} </ref><ref name="pmid17208676">{{cite journal| author=Schima W| title=MRI of the pancreas: tumours and tumour-simulating processes. | journal=Cancer Imaging | year= 2006 | volume= 6 | issue=  | pages= 199-203 | pmid=17208676 | doi=10.1102/1470-7330.2006.0035 | pmc=1766565 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17208676  }} </ref><ref name="pmid22811847">{{cite journal| author=Tummala P, Junaidi O, Agarwal B| title=Imaging of pancreatic cancer: An overview. | journal=J Gastrointest Oncol | year= 2011 | volume= 2 | issue= 3 | pages= 168-74 | pmid=22811847 | doi=10.3978/j.issn.2078-6891.2011.036 | pmc=3397617 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22811847  }} </ref>
*MRI is considered when there is a diagnostic difficulty even after performing a CT scan.
*MRI is helpful in staging the extent and spread of pancreatic carcinoma rather than for detecting tumors or lesions less than 2 cm in size.
*MRI also helps in avoiding the radiation exposure when compared to a CT scan.
*MRI scan while determining pancreatic adenocarcinoma relies on the assessment of the size, shape, contour of the gland.
*Gadolinium is the contrast material most commonly used in the contrast MRI scan of the pancreas.
*MRI is helpful in characterizing cystic lesions of the pancreas and can aid in arriving at the diagnosis.
*Pancreatic cancer shows hypointense lesions on gadolinium-enhanced T1-weighted images.
*For the complete evaluation of the pancreatic parenchyma and the pancreaticobiliary ductal system, the following magnetic resonance sequences is advised:
**T1-weighted gradient-echo; T2-weighted axial and coronal sequences, usually turbo spin-echo; two dimensional (2D) and three dimensional (3D) MRCP
**T1-weighted 3D gradient-echo (GRE) before and after intravenous administration of gadolinium.
*Diffusion-weighted imaging (DWI) nowadays is being widely used.


==References==
==References==

Revision as of 22:47, 15 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]Faizan Sheraz, M.D. [3]

Overview

MRI

MRI: [1] [2][3][4][1]

  • MRI is considered when there is a diagnostic difficulty even after performing a CT scan.
  • MRI is helpful in staging the extent and spread of pancreatic carcinoma rather than for detecting tumors or lesions less than 2 cm in size.
  • MRI also helps in avoiding the radiation exposure when compared to a CT scan.
  • MRI scan while determining pancreatic adenocarcinoma relies on the assessment of the size, shape, contour of the gland.
  • Gadolinium is the contrast material most commonly used in the contrast MRI scan of the pancreas.
  • MRI is helpful in characterizing cystic lesions of the pancreas and can aid in arriving at the diagnosis.
  • Pancreatic cancer shows hypointense lesions on gadolinium-enhanced T1-weighted images.
  • For the complete evaluation of the pancreatic parenchyma and the pancreaticobiliary ductal system, the following magnetic resonance sequences is advised:
    • T1-weighted gradient-echo; T2-weighted axial and coronal sequences, usually turbo spin-echo; two dimensional (2D) and three dimensional (3D) MRCP
    • T1-weighted 3D gradient-echo (GRE) before and after intravenous administration of gadolinium.
  • Diffusion-weighted imaging (DWI) nowadays is being widely used.

References

  1. 1.0 1.1 Tummala P, Junaidi O, Agarwal B (2011). "Imaging of pancreatic cancer: An overview". J Gastrointest Oncol. 2 (3): 168–74. doi:10.3978/j.issn.2078-6891.2011.036. PMC 3397617. PMID 22811847.
  2. Lee ES, Lee JM (2014). "Imaging diagnosis of pancreatic cancer: a state-of-the-art review". World J Gastroenterol. 20 (24): 7864–77. doi:10.3748/wjg.v20.i24.7864. PMC 4069314. PMID 24976723.
  3. Sahani DV, Bonaffini PA, Catalano OA, Guimaraes AR, Blake MA (2012). "State-of-the-art PET/CT of the pancreas: current role and emerging indications". Radiographics. 32 (4): 1133–58, discussion 1158-60. doi:10.1148/rg.324115143. PMID 22786999.
  4. Schima W (2006). "MRI of the pancreas: tumours and tumour-simulating processes". Cancer Imaging. 6: 199–203. doi:10.1102/1470-7330.2006.0035. PMC 1766565. PMID 17208676.