Pancoast tumor overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

A pancoast tumor, also known as superior sulcus tumor, defined primarily by its location at the pulmonary apex. The tumor can cause compression of a brachiocephalic vein, subclavian artery, phrenic nerve, recurrent laryngeal nerve, or, compression of a sympathetic ganglion.

Historical Perspective

Pancoast tumor was first described by Hare in 1838. In 1924, Henry K. Pancoast discovered the association between apical chest tumors, characteristic pain distribution, and Horner’s syndrome. In 1954, external beam radiation was used for the treatment of associated pain by Haas and colleagues. In 1990’s a combination of chemotherapy and radiotherapy was found to be associated with better prognosis and treatment outcome.

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