PRKAR1B

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Protein kinase, cAMP-dependent, regulatory, type I, beta
Identifiers
Symbols PRKAR1B ; PRKAR1
External IDs Template:OMIM5 Template:MGI HomoloGene37665
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Protein kinase, cAMP-dependent, regulatory, type I, beta, also known as PRKAR1B, is a human gene.[1]


References

  1. "Entrez Gene: PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta".

Further reading

  • Harrich D, McMillan N, Munoz L; et al. (2007). "Will diverse Tat interactions lead to novel antiretroviral drug targets?". Current drug targets. 7 (12): 1595–606. PMID 17168834.
  • Solberg R, Sistonen P, Träskelin AL; et al. (1992). "Mapping of the regulatory subunits RI beta and RII beta of cAMP-dependent protein kinase genes on human chromosome 7". Genomics. 14 (1): 63–9. PMID 1358799.
  • Solberg R, Taskén K, Keiserud A, Jahnsen T (1991). "Molecular cloning, cDNA structure and tissue-specific expression of the human regulatory subunit RI beta of cAMP-dependent protein kinases". Biochem. Biophys. Res. Commun. 176 (1): 166–72. PMID 1708242.
  • Hofmann B, Nishanian P, Baldwin RL; et al. (1991). "HIV inhibits the early steps of lymphocyte activation, including initiation of inositol phospholipid metabolism". J. Immunol. 145 (11): 3699–705. PMID 1978848.
  • Scambler P, Oyen O, Wainwright B; et al. (1987). "Exclusion of catalytic and regulatory subunits of cAMP-dependent protein kinase as candidate genes for the defect causing cystic fibrosis". Am. J. Hum. Genet. 41 (5): 925–32. PMID 3479018.
  • Hofmann B, Nishanian P, Nguyen T; et al. (1993). "Human immunodeficiency virus proteins induce the inhibitory cAMP/protein kinase A pathway in normal lymphocytes". Proc. Natl. Acad. Sci. U.S.A. 90 (14): 6676–80. PMID 7688126.
  • Solberg R, Taskén K, Wen W; et al. (1994). "Human regulatory subunit RI beta of cAMP-dependent protein kinases: expression, holoenzyme formation and microinjection into living cells". Exp. Cell Res. 214 (2): 595–605. doi:10.1006/excr.1994.1297. PMID 7925653.
  • Hofmann B, Nishanian P, Fan J; et al. (1994). "HIV Gag p17 protein impairs proliferation of normal lymphocytes in vitro". AIDS. 8 (7): 1016–7. PMID 7946090.
  • Taskén K, Skålhegg BS, Solberg R; et al. (1993). "Novel isozymes of cAMP-dependent protein kinase exist in human cells due to formation of RI alpha-RI beta heterodimeric complexes". J. Biol. Chem. 268 (28): 21276–83. PMID 8407966.
  • Swingler S, Gallay P, Camaur D; et al. (1997). "The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix". J. Virol. 71 (6): 4372–7. PMID 9151826.
  • Chen P, Mayne M, Power C, Nath A (1997). "The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases". J. Biol. Chem. 272 (36): 22385–8. PMID 9278385.
  • Zidovetzki R, Wang JL, Chen P; et al. (1998). "Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase C- and cAMP-dependent protein kinase pathways". AIDS Res. Hum. Retroviruses. 14 (10): 825–33. PMID 9671211.
  • Mayne M, Bratanich AC, Chen P; et al. (1998). "HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease". Neuroimmunomodulation. 5 (3–4): 184–92. PMID 9730685.
  • Laxminarayana D, Khan IU, Mishra N; et al. (1999). "Diminished levels of protein kinase A RI alpha and RI beta transcripts and proteins in systemic lupus erythematosus T lymphocytes". J. Immunol. 162 (9): 5639–48. PMID 10228048.
  • Adachi M, Lewis EJ (2002). "The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status". J. Biol. Chem. 277 (25): 22915–24. doi:10.1074/jbc.M201695200. PMID 11943777.
  • Oliver CJ, Terry-Lorenzo RT, Elliott E; et al. (2002). "Targeting protein phosphatase 1 (PP1) to the actin cytoskeleton: the neurabin I/PP1 complex regulates cell morphology". Mol. Cell. Biol. 22 (13): 4690–701. PMID 12052877.
  • Nguyen DT, Rovira II, Finkel T (2002). "Regulation of the Werner helicase through a direct interaction with a subunit of protein kinase A.". FEBS Lett. 521 (1–3): 170–4. PMID 12067711.
  • Mucignat-Caretta C, Caretta A (2003). "Localization of Triton-insoluble cAMP-dependent kinase type RIbeta in rat and mouse brain". J. Neurocytol. 30 (11): 885–94. PMID 12373096.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Carlson CR, Ruppelt A, Taskén K (2003). "A kinase anchoring protein (AKAP) interaction and dimerization of the RIalpha and RIbeta regulatory subunits of protein kinase a in vivo by the yeast two hybrid system". J. Mol. Biol. 327 (3): 609–18. PMID 12634056.

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