PCYT1B: Difference between revisions

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{{Underlinked|date=March 2014}}
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'''Choline-phosphate cytidylyltransferase B''' is an [[enzyme]] that in humans is encoded by the ''PCYT1B'' [[gene]].<ref name="pmid9593753">{{cite journal | vauthors = Lykidis A, Murti KG, Jackowski S | title = Cloning and characterization of a second human CTP:phosphocholine cytidylyltransferase | journal = J Biol Chem | volume = 273 | issue = 22 | pages = 14022–9 |date=Jul 1998 | pmid = 9593753 | pmc =  | doi =10.1074/jbc.273.22.14022 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PCYT1B phosphate cytidylyltransferase 1, choline, beta| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9468| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source = 
| PDB =
| Name = Phosphate cytidylyltransferase 1, choline, beta
| HGNCid = 8755
| Symbol = PCYT1B
| AltSymbols =; CTB; CCT-beta
| OMIM = 604926
| ECnumber = 
| Homologene = 3564
| MGIid = 2147987
| GeneAtlas_image1 = PBB_GE_PCYT1B_206751_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_PCYT1B_210456_at_tn.png
| Function = {{GNF_GO|id=GO:0004105 |text = choline-phosphate cytidylyltransferase activity}}{{GNF_GO|id=GO:0016740 |text = transferase activity}}
| Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005783 |text = endoplasmic reticulum}}
| Process = {{GNF_GO|id=GO:0001541 |text = ovarian follicle development}} {{GNF_GO|id=GO:0006656 |text = phosphatidylcholine biosynthetic process}} {{GNF_GO|id=GO:0007283 |text = spermatogenesis}} {{GNF_GO|id=GO:0008654 |text = phospholipid biosynthetic process}} {{GNF_GO|id=GO:0009058 |text = biosynthetic process}}
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9468
    | Hs_Ensembl = ENSG00000102230
    | Hs_RefseqProtein = NP_004836
    | Hs_RefseqmRNA = NM_004845
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = X
    | Hs_GenLoc_start = 24486125
    | Hs_GenLoc_end = 24600715
    | Hs_Uniprot = Q9Y5K3
    | Mm_EntrezGene = 236899
    | Mm_Ensembl = ENSMUSG00000035246
    | Mm_RefseqmRNA = NM_177546
    | Mm_RefseqProtein = NP_808214
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = X
    | Mm_GenLoc_start = 89927831
    | Mm_GenLoc_end = 90002667
    | Mm_Uniprot = Q811Q9
  }}
}}
'''Phosphate cytidylyltransferase 1, choline, beta''', also known as '''PCYT1B''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PCYT1B phosphate cytidylyltransferase 1, choline, beta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9468| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Ballif BA, Villén J, Beausoleil SA, ''et al.'' |title=Phosphoproteomic analysis of the developing mouse brain. |journal=Mol. Cell Proteomics |volume=3 |issue= 11 |pages= 1093-101 |year= 2005 |pmid= 15345747 |doi= 10.1074/mcp.M400085-MCP200 }}
*{{cite journal   |vauthors=Ballif BA, Villén J, Beausoleil SA, etal |title=Phosphoproteomic analysis of the developing mouse brain |journal=Mol. Cell. Proteomics |volume=3 |issue= 11 |pages= 1093–101 |year= 2005 |pmid= 15345747 |doi= 10.1074/mcp.M400085-MCP200 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Llorca O, Martín-Benito J, Gómez-Puertas P, ''et al.'' |title=Analysis of the interaction between the eukaryotic chaperonin CCT and its substrates actin and tubulin. |journal=J. Struct. Biol. |volume=135 |issue= 2 |pages= 205-18 |year= 2002 |pmid= 11580270 |doi= 10.1006/jsbi.2001.4359 }}
*{{cite journal   |vauthors=Llorca O, Martín-Benito J, Gómez-Puertas P, etal |title=Analysis of the interaction between the eukaryotic chaperonin CCT and its substrates actin and tubulin |journal=J. Struct. Biol. |volume=135 |issue= 2 |pages= 205–18 |year= 2002 |pmid= 11580270 |doi= 10.1006/jsbi.2001.4359 }}
*{{cite journal | author=McCormack EA, Llorca O, Carrascosa JL, ''et al.'' |title=Point mutations in a hinge linking the small and large domains of beta-actin result in trapped folding intermediates bound to cytosolic chaperonin CCT. |journal=J. Struct. Biol. |volume=135 |issue= 2 |pages= 198-204 |year= 2002 |pmid= 11580269 |doi= 10.1006/jsbi.2001.4385 }}
*{{cite journal   |vauthors=McCormack EA, Llorca O, Carrascosa JL, etal |title=Point mutations in a hinge linking the small and large domains of beta-actin result in trapped folding intermediates bound to cytosolic chaperonin CCT |journal=J. Struct. Biol. |volume=135 |issue= 2 |pages= 198–204 |year= 2002 |pmid= 11580269 |doi= 10.1006/jsbi.2001.4385 }}
*{{cite journal  | author=Lykidis A, Baburina I, Jackowski S |title=Distribution of CTP:phosphocholine cytidylyltransferase (CCT) isoforms. Identification of a new CCTbeta splice variant. |journal=J. Biol. Chem. |volume=274 |issue= 38 |pages= 26992-7001 |year= 1999 |pmid= 10480912 |doi=  }}
*{{cite journal  | vauthors=Lykidis A, Baburina I, Jackowski S |title=Distribution of CTP:phosphocholine cytidylyltransferase (CCT) isoforms. Identification of a new CCTbeta splice variant |journal=J. Biol. Chem. |volume=274 |issue= 38 |pages= 26992–7001 |year= 1999 |pmid= 10480912 |doi=10.1074/jbc.274.38.26992 }}
*{{cite journal  | author=Gubin AN, Njoroge JM, Bouffard GG, Miller JL |title=Gene expression in proliferating human erythroid cells. |journal=Genomics |volume=59 |issue= 2 |pages= 168-77 |year= 1999 |pmid= 10409428 |doi= 10.1006/geno.1999.5855 }}
*{{cite journal  | vauthors=Gubin AN, Njoroge JM, Bouffard GG, Miller JL |title=Gene expression in proliferating human erythroid cells |journal=Genomics |volume=59 |issue= 2 |pages= 168–77 |year= 1999 |pmid= 10409428 |doi= 10.1006/geno.1999.5855 }}
*{{cite journal  | author=Lykidis A, Murti KG, Jackowski S |title=Cloning and characterization of a second human CTP:phosphocholine cytidylyltransferase. |journal=J. Biol. Chem. |volume=273 |issue= 22 |pages= 14022-9 |year= 1998 |pmid= 9593753 |doi=  }}
}}
}}
{{refend}}
{{refend}}


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Revision as of 17:47, 7 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Choline-phosphate cytidylyltransferase B is an enzyme that in humans is encoded by the PCYT1B gene.[1][2]


References

  1. ↑ Lykidis A, Murti KG, Jackowski S (Jul 1998). "Cloning and characterization of a second human CTP:phosphocholine cytidylyltransferase". J Biol Chem. 273 (22): 14022–9. doi:10.1074/jbc.273.22.14022. PMID 9593753.
  2. ↑ "Entrez Gene: PCYT1B phosphate cytidylyltransferase 1, choline, beta".

Further reading



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