PASK
PAS domain containing serine/threonine kinase | |||||||||||||
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File:PBB Protein PASK image.jpg PDB rendering based on 1ll8. | |||||||||||||
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Identifiers | |||||||||||||
Symbols | PASK ; DKFZP434O051; DKFZp686P2031; KIAA0135; PASKIN; STK37 | ||||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 9038 | ||||||||||||
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RNA expression pattern | |||||||||||||
File:PBB GE PASK 213534 s at tn.png | |||||||||||||
File:PBB GE PASK 216945 x at tn.png | |||||||||||||
More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Template:GNF Ortholog box | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | n/a | n/a | |||||||||||
Ensembl | n/a | n/a | |||||||||||
UniProt | n/a | n/a | |||||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||||
RefSeq (protein) | n/a | n/a | |||||||||||
Location (UCSC) | n/a | n/a | |||||||||||
PubMed search | n/a | n/a |
PAS domain containing serine/threonine kinase, also known as PASK, is a human gene.[1]
PAS domains regulate the function of many intracellular signaling pathways in response to both extrinsic and intrinsic stimuli. PASK is an evolutionarily conserved protein present in yeast, flies, and mammals.[supplied by OMIM][1]
References
Further reading
- Nakajima D, Okazaki N, Yamakawa H; et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. PMID 12168954.
- Nagase T, Seki N, Tanaka A; et al. (1996). "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (4): 167–74, 199–210. PMID 8590280.
- Andersson B, Wentland MA, Ricafrente JY; et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
- Yu W, Andersson B, Worley KC; et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. PMID 9110174.
- Ceulemans H, Van Eynde A, Pérez-Callejón E; et al. (1999). "Structure and splice products of the human gene encoding sds22, a putative mitotic regulator of protein phosphatase-1". Eur. J. Biochem. 262 (1): 36–42. PMID 10231361.
- Rutter J, Michnoff CH, Harper SM; et al. (2001). "PAS kinase: an evolutionarily conserved PAS domain-regulated serine/threonine kinase". Proc. Natl. Acad. Sci. U.S.A. 98 (16): 8991–6. doi:10.1073/pnas.161284798. PMID 11459942.
- Hofer T, Spielmann P, Stengel P; et al. (2001). "Mammalian PASKIN, a PAS-serine/threonine kinase related to bacterial oxygen sensors". Biochem. Biophys. Res. Commun. 288 (4): 757–64. doi:10.1006/bbrc.2001.5840. PMID 11688972.
- Amezcua CA, Harper SM, Rutter J, Gardner KH (2003). "Structure and interactions of PAS kinase N-terminal PAS domain: model for intramolecular kinase regulation". Structure. 10 (10): 1349–61. PMID 12377121.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- da Silva Xavier G, Rutter J, Rutter GA (2004). "Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose". Proc. Natl. Acad. Sci. U.S.A. 101 (22): 8319–24. doi:10.1073/pnas.0307737101. PMID 15148392.
- Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Ewing RM, Chu P, Elisma F; et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.
- Eckhardt K, Troger J, Reissmann J; et al. (2007). "Male germ cell expression of the PAS domain kinase PASKIN and its novel target eukaryotic translation elongation factor eEF1A1". Cell. Physiol. Biochem. 20 (1–4): 227–40. doi:10.1159/000104169. PMID 17595531.
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