Osteoporosis epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Raviteja Guddeti, M.B.B.S.[3]

Overview

Osteoporosis is a major health problem affecting 44 million male and female patients in the United States. The disease is more common in females aged over 50 years.

Prevalence

In developed countries, the average prevalence of osteoporosis is 3871 per 100,000 patients. While osteoporosis occurs in people from all ethnic groups, European or Asian ancestry predisposes an individual for osteoporosis.[1] People of African descent have a lower fracture risk compared to Caucasians and Asians.

Age

Osteoporosis affects 55% of Americans aged 50 and above. The prevalence of osteoporosis increases with age. Fracture risk increases after the sixth decade of life. The highest incidence is found among men and women ages 80 or older.

Gender

Females are more prone to develop osteoporosis than men. Lifetime risk of fractures is three times more in women than in men, but men are associated with higher mortality rates than that of women.


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [4], Farman Khan, MD, MRCP [5]

Epidemiology of osteoporosis in Men

Roughly around 1.5 million men over the age of 65 in the United States have osteoporosis, and another 3.5 million men are at risk of developing osteoporosis.In about 40 to 60 % of men who have osteoporotic fractures, causes for osteoporosis can be identified.The most common identifiable causes of osteoporosis include Hypogonadism, glucocorticoid therapy,vitamin D deficiency, anti-convulsant drug therapy, hypercalciuria, and alcohol abuse,gastrointestinal diseases.


References

  1. Melton LJ (2003). "Epidemiology worldwide". Endocrinol. Metab. Clin. North Am. 32 (1): 1–13, v. PMID 12699289.



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