OR8K3: Difference between revisions

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'''Olfactory receptor, family 8, subfamily K, member 3''', also known as '''OR8K3''', is a [[protein]] which in humans is encoded by the ''OR8K3'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR8K3 olfactory receptor, family 8, subfamily K, member 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=219473| accessdate = }}; {{NLM content}}</ref>
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== Function ==
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[[Olfactory receptor]]s interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of [[G protein-coupled receptor]]s (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez"/>
{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Olfactory receptor, family 8, subfamily K, member 3
| HGNCid = 15313
| Symbol = OR8K3
| AltSymbols =; OR11-181
| OMIM = 
| ECnumber = 
| Homologene = 51783
| MGIid = 3030881
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 219473
    | Hs_Ensembl = ENSG00000181689
    | Hs_RefseqProtein = NP_001005202
    | Hs_RefseqmRNA = NM_001005202
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 11
    | Hs_GenLoc_start = 55842359
    | Hs_GenLoc_end = 55843297
    | Hs_Uniprot = Q8NH51
    | Mm_EntrezGene = 259014
    | Mm_Ensembl = ENSMUSG00000075196
    | Mm_RefseqmRNA = XM_001001926
    | Mm_RefseqProtein = XP_001001926
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 2
    | Mm_GenLoc_start = 86028849
    | Mm_GenLoc_end = 86029808
    | Mm_Uniprot = 
  }}
}}
'''Olfactory receptor, family 8, subfamily K, member 3''', also known as '''OR8K3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR8K3 olfactory receptor, family 8, subfamily K, member 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=219473| accessdate = }}</ref>


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== References ==
{{PBB_Summary
{{reflist}}
| section_title =  
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR8K3 olfactory receptor, family 8, subfamily K, member 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=219473| accessdate = }}</ref>
}}


==References==
{{reflist|2}}
==Further reading==
==Further reading==
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{{refbegin | 2}}
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| citations =  
| citations =  
*{{cite journal  | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi=  }}
*{{cite journal  | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100  | pmc=356993 }}
}}
}}
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* {{MeshName|OR8K3+protein,+human}}
* {{MeshName|OR8K3+protein,+human}}


{{NLM content}}
{{membrane-protein-stub}}
{{Olfactory receptors}}
{{Olfactory receptors}}
[[Category:G protein coupled receptors]]
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[[Category:Olfactory receptors]]
 
 
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Latest revision as of 02:47, 27 October 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Olfactory receptor, family 8, subfamily K, member 3, also known as OR8K3, is a protein which in humans is encoded by the OR8K3 gene.[1]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

References

  1. ↑ 1.0 1.1 "Entrez Gene: OR8K3 olfactory receptor, family 8, subfamily K, member 3".; This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Further reading

External links


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