OR1F1: Difference between revisions

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{{Infobox_gene}}
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'''Olfactory receptor 1F1''' is a [[protein]] that in humans is encoded by the ''OR1F1'' [[gene]].<ref name="pmid9288094">{{cite journal | author =  | title = A candidate gene for familial Mediterranean fever | journal = Nat Genet | volume = 17 | issue = 1 | pages = 25–31 |date=Oct 1997 | pmid = 9288094 | pmc =  | doi = 10.1038/ng0997-25 | last1 French Fmf | first1 Consortium }}</ref><ref name="pmid9500546">{{cite journal |vauthors=Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D | title = Distribution of olfactory receptor genes in the human genome | journal = Nat Genet | volume = 18 | issue = 3 | pages = 243–50 |date=Mar 1998 | pmid = 9500546 | pmc =  | doi = 10.1038/ng0398-243 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: OR1F1 olfactory receptor, family 1, subfamily F, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4992| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
  | image_source =
| PDB =  
| Name = Olfactory receptor, family 1, subfamily F, member 1
| HGNCid = 8194
| Symbol = OR1F1
| AltSymbols =; OLFMF; OR16-36; OR16-37; OR16-88; OR16-89; OR16-90; OR1F10; OR1F13P; OR1F4; OR1F5; OR1F6; OR1F7; OR1F8; OR1F9; OR3-145; ORL1023
| OMIM = 603232
| ECnumber =
  | Homologene = 69122
| MGIid =   
| GeneAtlas_image1 = PBB_GE_OR1F1_221402_at_tn.png
  | Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 4992
    | Hs_Ensembl = ENSG00000168124
    | Hs_RefseqProtein = NP_036492
    | Hs_RefseqmRNA = NM_012360
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 16
    | Hs_GenLoc_start = 3194248
    | Hs_GenLoc_end = 3195189
    | Hs_Uniprot = O43749
    | Mm_EntrezGene = 
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = 
    | Mm_RefseqProtein = 
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
    | Mm_Uniprot = 
  }}
}}
'''Olfactory receptor, family 1, subfamily F, member 1''', also known as '''OR1F1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR1F1 olfactory receptor, family 1, subfamily F, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4992| accessdate = }}</ref>


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| section_title =  
| section_title =  
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR1F1 olfactory receptor, family 1, subfamily F, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4992| accessdate = }}</ref>
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez" />
}}
}}


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==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
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| citations =  
| citations =  
*{{cite journal  | author= |title=A candidate gene for familial Mediterranean fever. The French FMF Consortium. |journal=Nat. Genet. |volume=17 |issue= 1 |pages= 25-31 |year= 1997 |pmid= 9288094 |doi= 10.1038/ng0997-25 }}
*{{cite journal  | author=Bernot A |title=A transcriptional Map of the FMF region |journal=Genomics |volume=50 |issue= 2 |pages= 147–60 |year= 1998 |pmid= 9653642 |doi=10.1006/geno.1998.5313 |name-list-format=vanc| author2=Heilig R  | author3=Clepet C  | display-authors=3 | last4=Smaoui  | first4=Nizar  | last5=Silva  | first5=Corinne Da | last6=Petit  | first6=Jean-Louis  | last7=Devaud  | first7=Catherine  | last8=Chiannilkulchai  | first8=Nuchanard  | last9=Fizames  | first9=Cécile }}
*{{cite journal | author=Rouquier S, Taviaux S, Trask BJ, ''et al.'' |title=Distribution of olfactory receptor genes in the human genome. |journal=Nat. Genet. |volume=18 |issue= 3 |pages= 243-50 |year= 1998 |pmid= 9500546 |doi= 10.1038/ng0398-243 }}
*{{cite journal  | author=Fuchs T |title=DEFOG: a practical scheme for deciphering families of genes |journal=Genomics |volume=80 |issue= 3 |pages= 295–302 |year= 2003 |pmid= 12213199 |doi=10.1006/geno.2002.6830  |name-list-format=vanc| author2=Malecova B  | author3=Linhart C  | display-authors=3  | last4=Sharan  | first4=Roded  | last5=Khen  | first5=Miriam  | last6=Herwig  | first6=Ralf  | last7=Shmulevich  | first7=Dmitry  | last8=Elkon  | first8=Rani  | last9=Steinfath  | first9=Matthias }}
*{{cite journal | author=Bernot A, Heilig R, Clepet C, ''et al.'' |title=A transcriptional Map of the FMF region. |journal=Genomics |volume=50 |issue= 2 |pages= 147-60 |year= 1998 |pmid= 9653642 |doi=  }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi=  }}
*{{cite journal  |vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100  | pmc=356993 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi=  }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
}}
{{refend}}
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{{NLM content}}
{{NLM content}}
{{membrane-protein-stub}}
 
{{Olfactory receptors}}
{{Olfactory receptors}}
[[Category:G protein coupled receptors]]
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[[Category:Olfactory receptors]]
 
 
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Latest revision as of 00:29, 7 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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n/a

RefSeq (protein)

n/a

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Olfactory receptor 1F1 is a protein that in humans is encoded by the OR1F1 gene.[1][2][3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

References

  1. French Fmf, Consortium (Oct 1997). "A candidate gene for familial Mediterranean fever". Nat Genet. 17 (1): 25–31. doi:10.1038/ng0997-25. PMID 9288094.
  2. Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546.
  3. 3.0 3.1 "Entrez Gene: OR1F1 olfactory receptor, family 1, subfamily F, member 1".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.