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==Overview==
==Overview==


Physical examination findings of non-small cell lung cancer will depend on the location of the tumor. Non-small cell lung cancer with central location may cause crackling sounds, focal wheezing, voice hoarseness, and tachypnea. Peripheral location can present with pleurisy findings, such as reduced chest expansion. Common physical examination of patients with non-small cell lung cancer, include: crackling or bubbling noises, decreased/absent [[breath sounds]], whispered pectoriloquy, and tachypnea.<ref name="pmid4813837">{{cite journal |vauthors=Hyde L, Hyde CI |title=Clinical manifestations of lung cancer |journal=Chest |volume=65 |issue=3 |pages=299–306 |year=1974 |pmid=4813837 |doi= |url=}}</ref>
Physical examination findings of non-small cell lung cancer will depend on the location of the tumor. Non-small cell lung cancer with central location may cause [[Crackles|crackling sounds]], [[Wheezing|focal wheezing]], [[Hoarseness|voice hoarseness]], and [[tachypnea]]. Peripheral location can present with [[Pleurisy physical examination|pleurisy findings]]. Common physical examination of patients with non-small cell lung cancer, include: crackling or bubbling noises, decreased/absent [[breath sounds]], and whispered pectoriloquy.


==Physical Examination==
==Physical Examination==
*The following physical examination findings may be present among patients with non-small cell lung cancer:<ref name="pmid4813837">{{cite journal |vauthors=Hyde L, Hyde CI |title=Clinical manifestations of lung cancer |journal=Chest |volume=65 |issue=3 |pages=299–306 |year=1974 |pmid=4813837 |doi= |url=}}</ref>
The following physical examination findings may be present among patients with non-small cell lung cancer:<ref name="pmid4813837">{{cite journal |vauthors=Hyde L, Hyde CI |title=Clinical manifestations of lung cancer |journal=Chest |volume=65 |issue=3 |pages=299–306 |year=1974 |pmid=4813837 |doi= |url=}}</ref><ref name="pmid25077084">{{cite journal |vauthors=Ouziane I, Boutayeb S, Mrabti H, Lalya I, Rimani M, Errihani H |title=Sarcomatoid carcinoma of the lung: a model of resistance of chemotherapy |journal=N Am J Med Sci |volume=6 |issue=7 |pages=342–5 |date=July 2014 |pmid=25077084 |pmc=4114013 |doi=10.4103/1947-2714.136920 |url=}}</ref>
* Physical examination findings of non small cell lung cancer can be completely normal during the early stage of malignancy.
* Patient may present with following findings in later stage of [[malignancy]]:


===General appearance===
===General appearance===
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===Vital Signs===
===Vital Signs===
* Low-grade [[fever]]
* Low-grade [[fever]]
* Decreased SPO2
* Decreased oxygen saturation at room air
* [[Tachypnea]]
* [[Tachypnea]]
* [[Tachycardia]]
* [[Tachycardia]]
===HEENT===
*[[Lymphadenopathy]]
===Skin===
*[[Pallor]]
*[[Acanthosis nigricans]]
===CNS===
*[[Slurred speech]]
*[[Confusion]]


===Chest===
===Chest===
'''Inspection'''
*Performed in the anterior chest/posterior chest
*Hoarseness
*Rapid rate of breathing
'''Auscultation'''  
'''Auscultation'''  
*Present pleural friction rub
*Present [[pleural friction rub]]
*Present egophony
*Present [[egophony]]
*Crackling or bubbling noises
*Crackling or bubbling noises
*Present whispered pectoriloquy
*Present whispered pectoriloquy
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*Hyporesonance  
*Hyporesonance  
*Dull percussion
*Dull percussion
*Tactile fremitus
*[[Tactile fremitus]]
*Reduced chest expansion
*Reduced [[chest expansion]]


===Abdomen===
===Abdomen===
*[[Hepatomegaly]]
*[[Hepatomegaly]]
===Back===
* Back examination of patients with non small cell lung cancer of the lung is usually normal.
===Genitourinary===
* Genitourinary examination of patients with non small cell lung cancer is usually normal.


===Musculoskeletal===
===Musculoskeletal===
* Palpable soft-tissue mass
* Palpable soft-tissue mass
===Skin===
*[[Pallor]]
===HEENT===
*[[Lymphadenopathy]]
===CNS===
*Slurred speech
*Confusion


===Extremities===
===Extremities===
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[[Category:Lung cancer]]
[[Category:Lung cancer]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Pulmonology]]
[[Category:Surgery]]

Latest revision as of 16:10, 9 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

Physical examination findings of non-small cell lung cancer will depend on the location of the tumor. Non-small cell lung cancer with central location may cause crackling sounds, focal wheezing, voice hoarseness, and tachypnea. Peripheral location can present with pleurisy findings. Common physical examination of patients with non-small cell lung cancer, include: crackling or bubbling noises, decreased/absent breath sounds, and whispered pectoriloquy.

Physical Examination

The following physical examination findings may be present among patients with non-small cell lung cancer:[1][2]

  • Physical examination findings of non small cell lung cancer can be completely normal during the early stage of malignancy.
  • Patient may present with following findings in later stage of malignancy:

General appearance

  • Well-appearing
  • Older age in relation to chronological age
  • Lethargic
  • Confused

Vital Signs

HEENT

Skin

CNS

Chest

Auscultation

Percussion

Abdomen

Back

  • Back examination of patients with non small cell lung cancer of the lung is usually normal.

Genitourinary

  • Genitourinary examination of patients with non small cell lung cancer is usually normal.

Musculoskeletal

  • Palpable soft-tissue mass

Extremities

References

  1. Hyde L, Hyde CI (1974). "Clinical manifestations of lung cancer". Chest. 65 (3): 299–306. PMID 4813837.
  2. Ouziane I, Boutayeb S, Mrabti H, Lalya I, Rimani M, Errihani H (July 2014). "Sarcomatoid carcinoma of the lung: a model of resistance of chemotherapy". N Am J Med Sci. 6 (7): 342–5. doi:10.4103/1947-2714.136920. PMC 4114013. PMID 25077084.


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