Non small cell lung cancer history and symptoms: Difference between revisions

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==Overview==
==Overview==


The hallmark of non-small cell lung cancer is chronic cough, weight loss, and hemoptysis. A positive history of smoking, exposure to asbestos, tuberculosis infection, or a high risk occupation may be suggestive of non-small cell lung cancer. Symptoms related with non-small cell lung cancer will vary depending on the size and location of the tumor. Common symptoms of non-small cell lung cancer may also include shortness of breath, fatigue, and chest pain.<ref name="pain"> Non small cell lung cancer. Wikipedia. https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma Accessed on February 24, 2016 </ref>
The hallmark of non-small cell lung cancer is [[Cough|chronic cough]], [[weight loss]], and [[hemoptysis]]. A positive history of [[smoking]], [[Asbestosis|exposure to asbestos]], [[tuberculosis infection]], or a [[Occupational safety and health|high risk occupation]] may be suggestive of non-small cell lung cancer. Symptoms related with non-small cell lung cancer will vary depending on the size and location of the tumor. Common symptoms of non-small cell lung cancer may also include [[shortness of breath]], [[fatigue]], and [[chest pain]].


==History==
==History==
*Obtaining the history is an important aspect of making a diagnosis of non-small cell lung cancer. It provides insight into natural evolution of the disease. Complete history will help determine the association with other conditions. Specific symptoms description such as duration, onset, and progression are important for making the diagnosis. Specific areas of focus when obtaining the history, are outlined below:<ref name="pmid11899115">{{cite journal |vauthors=Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J |title=The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study |journal=Cancer Causes Control |volume=13 |issue=1 |pages=27–34 |year=2002 |pmid=11899115 |doi= |url=}}</ref>
Obtaining the history is an important aspect of making a diagnosis of non-small cell lung cancer.  
*Family history of cancer
* Past medical, social and family history provides important insight into natural evolution of the disease.
*Personal history of cancer
* Complete history will help determine the likelihood of metastases and the association with other conditions.  
:*Colorectal cancer
* Specific areas of focus when obtaining the history, are outlined below:<ref name="pmid11899115">{{cite journal |vauthors=Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J |title=The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study |journal=Cancer Causes Control |volume=13 |issue=1 |pages=27–34 |year=2002 |pmid=11899115 |doi= |url=}}</ref><ref name="pmid17505036">{{cite journal |vauthors=Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM |title=Natural history of stage I non-small cell lung cancer: implications for early detection |journal=Chest |volume=132 |issue=1 |pages=193–9 |year=2007 |pmid=17505036 |doi=10.1378/chest.06-3096 |url=}}</ref>
:*Bladder cancer  
** '''Past medical history:'''
:*Breast cancer
*** Previous primary infection of [[tuberculosis]]
:*Prostate cancer
*** [[Colorectal cancer]]
*Positive history of active/passive smoking
***[[Bladder cancer]]
:*Number of cigarettes/year  
***[[Breast cancer]]
:*Number of years/months of active smoking
***[[Prostate cancer]]
:*Number of years/months of smoking cessation  
**'''Social history:'''
*Previous primary infection of tuberculosis
***Positive history of active/passive smoking
*Positive family history of the following syndromes:
***Number of cigarettes/year
:*Li-Fraumeni syndrome  
***Number of years/months of active smoking
:*Noonan syndrome
***Number of years/months of [[smoking cessation]]
**'''Family history:'''
***Positive family history for cancer
***Positive family history for following syndromes:
****[[Li-Fraumeni syndrome]]
****[[Noonan syndrome]]


==Common Symptoms==
==Common Symptoms==
*The majority of non-small cell lung cancers are asymptomatic and are usually found incidentally.<ref name="pain"> Non small cell lung cancer. Wikipedia. https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma Accessed on February 24, 2016 </ref>
The majority of non-small cell lung cancers are [[asymptomatic]] and are usually found incidentally. The hallmark of non-small cell lung cancer is chronic cough, weight loss, and hemoptysis.<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors =  Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref><ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015</ref>
*The hallmark of non-small cell lung cancer is chronic cough, weight loss, and hemoptysis.
*Symptoms that suggest non small cell lung cancer include:
*Other symptoms that suggest non small cell lung cancer, include:<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors =  Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref><ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015</ref>
** Chronic [[cough]]  
:* [[Dyspnea]]  
** [[Dyspnea]]  
:* [[Hemoptysis]]  
** [[Hemoptysis]]  
:* Chronic [[coughing]]
** [[Chest pain]]
:* [[Wheezing]]
** [[Abdominal pain]]
:* [[Chest pain]]
** [[Fatigue]]
:* [[Abdominal pain]]
** [[Weight loss]]
:* [[Cachexia]]  
** [[Anorexia|Loss of appetite]]
:* [[Fatigue]]
** [[Dysphonia]]
:* Loss of [[appetite]]
:* [[Dysphonia]]  
 
==Less Common Symptoms==
==Less Common Symptoms==
 
Other less common symptoms of non-small cell lung cancer include:<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors =  Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref><ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015</ref>
*Other less common symptoms of non-small cell lung cancer, include:  
* Symptoms during later stage of non-small cell lung cancer include:
'''Late Symptoms'''
** [[Bone pain]]
:* [[Bone pain]]
** [[Dysphagia]]
:* [[Dysphagia]]
** [[Fatigue]]
:* [[Fatigue]]
** [[Paresthesia|Numbness in extremities]]
:* Numbness in extremities
** [[Dizziness]]
:* [[Dizziness]]
** [[Seizure]]
:* [[Seizure]]
 


==References==
==References==
{{reflist|2}}
{{reflist|2}}


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Latest revision as of 15:57, 9 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

The hallmark of non-small cell lung cancer is chronic cough, weight loss, and hemoptysis. A positive history of smoking, exposure to asbestos, tuberculosis infection, or a high risk occupation may be suggestive of non-small cell lung cancer. Symptoms related with non-small cell lung cancer will vary depending on the size and location of the tumor. Common symptoms of non-small cell lung cancer may also include shortness of breath, fatigue, and chest pain.

History

Obtaining the history is an important aspect of making a diagnosis of non-small cell lung cancer.

  • Past medical, social and family history provides important insight into natural evolution of the disease.
  • Complete history will help determine the likelihood of metastases and the association with other conditions.
  • Specific areas of focus when obtaining the history, are outlined below:[1][2]

Common Symptoms

The majority of non-small cell lung cancers are asymptomatic and are usually found incidentally. The hallmark of non-small cell lung cancer is chronic cough, weight loss, and hemoptysis.[3][4]

Less Common Symptoms

Other less common symptoms of non-small cell lung cancer include:[3][4]

References

  1. ↑ Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J (2002). "The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study". Cancer Causes Control. 13 (1): 27–34. PMID 11899115.
  2. ↑ Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM (2007). "Natural history of stage I non-small cell lung cancer: implications for early detection". Chest. 132 (1): 193–9. doi:10.1378/chest.06-3096. PMID 17505036.
  3. ↑ 3.0 3.1 Hamilton, W (Dec 2005). "What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study". Thorax. BMJ Publishing Group Ltd. 60 (12): 1059–1065. PMID 16227326. Unknown parameter |coauthors= ignored (help)
  4. ↑ 4.0 4.1 Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015


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