Non small cell lung cancer epidemiology and demographics: Difference between revisions

Jump to navigation Jump to search
 
(35 intermediate revisions by 5 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Non small cell lung cancer}}
{{Non small cell lung cancer}}
{{CMG}}; {{AE}} {{SC}}
{{CMG}}; {{AE}} {{SC}} {{MV}}
==Overview==
==Overview==
Non-small cell lung cancer is the most common cancer worldwide and the leading cause of [[Mortality|cancer-related mortality]] in the United States. Non-small cell lung cancer accounted for 1.8 million new cases and 1.6 million deaths of lung cancer in 2012. In the United States, the age-adjusted [[prevalence]] of non-small cell lung cancer is  47.2 per 100,000 individuals. The median age at diagnosis of non-small cell lung cancer is 70 years. Non-small cell lung cancer is most frequently diagnosed among people between 65 to 74 years old. Males are more commonly affected by non-small cell lung cancer than females. The male to female ratio is approximately 1.8 to 1. The rate of new cases in 2011 showed that males develop lung cancer more often than females (64.8 and 48.6 per 100,000 individuals). There is a racial preponderance to the development of non-small cell lung cancer, where African American individuals are at a significantly increased risk compared to Caucasian race.
==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Prevalence===
===Prevalence===
* The age-adjusted prevalence of [[lung cancer]] is approximately 58.7 per 100,000 individuals worldwide based on 2008-2012 cases.<ref name=seer>Lung caner. Surveillance, Epidemiology, and End Results Program 2015. http://seer.cancer.gov/statfacts/html/lungb.html </ref>
* In the United States, the age-adjusted [[prevalence]] of non-small cell lung cancer is 47.2 per 100,000 indivudals.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/statfacts/html/lungb.html, based on November 2013 SEER data submission, posted to the SEER web site. February 2016.</ref>
* The most common type of lung cancer is non–small cell lung cancer (NSCLC). About 85%–90% of all lung cancers are non–small cell lung cancer. The other 10%–15% are small cell lung cancer.<ref>Non small cell lung cancer. Canadian cancer society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/lung-cancer/non-small-cell-lung-cancer/?region=ab </ref>
* About 85%–90% of all lung cancers are non-small cell lung cancer.<ref>Non small cell lung cancer. Canadian cancer society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/lung-cancer/non-small-cell-lung-cancer/?region=ab </ref>
* The most common type of lung cancer is non-small cell lung cancer.<ref name="pmid18452692">{{cite journal |vauthors=Molina JR, Yang P, Cassivi SD, Schild SE, Adjei AA |title=Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship |journal=Mayo Clin. Proc. |volume=83 |issue=5 |pages=584–94 |year=2008 |pmid=18452692 |pmc=2718421 |doi=10.4065/83.5.584 |url=}}</ref><ref name="lung">Tumors of the lung: epidemiology. WHO/IARC. 2006 https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb10/bb10-chap1.pdf Accessed on February 21, 2016</ref>
** Non-small cell lung cancer is the most common cancer worldwide, accounting for 1.8 million new cases and 1.6 million deaths in 2012.
**Adenocarcinoma of the lung is the most common non-small cell lung cancer subtype in the United States.


===Incidence===
===Incidence===
* The age-adjusted [[incidence]] of non-small cell lung cancer in 2012 was estimated to be 58.7  per 100,000 individuals in the United States.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 2008-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
** The incidence rate of [[Adenocarcinoma of the lung|lung adenocarcinoma]] is 22.1 per 100,000 individuals a year.
** The incidence rate of [[Squamous-cell carcinoma|lung squamous-cell carcinoma]] is 14.4 per 100,000 individuals a year.
===Age===
* The incidence of non small cell lung cancer increases with age; the [[median]] age at diagnosis is 70 years.<ref name="pmid19934774">{{cite journal |vauthors=Subramanian J, Morgensztern D, Goodgame B, Baggstrom MQ, Gao F, Piccirillo J, Govindan R |title=Distinctive characteristics of non-small cell lung cancer (NSCLC) in the young: a surveillance, epidemiology, and end results (SEER) analysis |journal=J Thorac Oncol |volume=5 |issue=1 |pages=23–8 |year=2010 |pmid=19934774 |doi=10.1097/JTO.0b013e3181c41e8d |url=}}</ref>
** Non small cell lung cancer is most frequently diagnosed among people among 65 to 74 years old.
** Shown below is an image that demonstrates the age-adjusted [[incidence]] of non-small cell lung cancer in the United States. These graphs are adapted from SEER: The Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.
===Gender===
* Males are more commonly affected with non-small cell lung cancer than females. The male to female ratio is approximately 1.8 to 1.<ref name="pmid19934774">{{cite journal |vauthors=Subramanian J, Morgensztern D, Goodgame B, Baggstrom MQ, Gao F, Piccirillo J, Govindan R |title=Distinctive characteristics of non-small cell lung cancer (NSCLC) in the young: a surveillance, epidemiology, and end results (SEER) analysis |journal=J Thorac Oncol |volume=5 |issue=1 |pages=23–8 |year=2010 |pmid=19934774 |doi=10.1097/JTO.0b013e3181c41e8d |url=}}</ref>
** The rate of new cases in 2011 showed that males develop lung cancer more often than females (64.8 and 48.6 per 100,000 individuals).
** Shown below is an image that demonstrates the relative proportions of common types of non-small cell lung cancer in the United States, by histology and gender. These graphs are adapted from SEER: The Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.
===Race===
*There is a racial preponderance to the development of non small cell lung cancer, where African American individuals are at a significantly increased risk compared to Caucasian race.<ref name="lung">Tumors of the lung: epidemiology. WHO/IARC. 2006 https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb10/bb10-chap1.pdf Accessed on February 21, 2016</ref>
** There is a higher prevalence of lung adenocarcinoma among Asian female patients with EGFR mutation (51.4%).
* Shown below is an image that demonstrates the mortality rate of non-small cell lung cancer among different ethnic groups in the United States. These graphs are adapted from SEER: The Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.<ref name="pmid19934774">{{cite journal |vauthors=Subramanian J, Morgensztern D, Goodgame B, Baggstrom MQ, Gao F, Piccirillo J, Govindan R |title=Distinctive characteristics of non-small cell lung cancer (NSCLC) in the young: a surveillance, epidemiology, and end results (SEER) analysis |journal=J Thorac Oncol |volume=5 |issue=1 |pages=23–8 |year=2010 |pmid=19934774 |doi=10.1097/JTO.0b013e3181c41e8d |url=}}</ref>


==References==
==References==
Line 15: Line 38:
[[Category:Hematology]]
[[Category:Hematology]]
[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Needs content]]
[[Category:Disease]]
[[Category:Disease]]


{{WikiDoc Help Menu}}
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}
{{WikiDoc Sources}}
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Pulmonology]]
[[Category:Surgery]]

Latest revision as of 20:09, 27 March 2018

Non Small Cell Lung Cancer Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Non Small Cell Lung Cancer from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-Ray

CT Scan

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Management Approach

Stage I
Stage II
Stage III
Stage IV
Metastatic Cancer

Medical Therapy

Chemotherapy
Radiation Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Non small cell lung cancer epidemiology and demographics On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Non small cell lung cancer epidemiology and demographics

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Non small cell lung cancer epidemiology and demographics

CDC on Non small cell lung cancer epidemiology and demographics

Non small cell lung cancer epidemiology and demographics in the news

Blogs on Non small cell lung cancer epidemiology and demographics

Directions to Hospitals Treating Non small cell carcinoma of the lung

Risk calculators and risk factors for Non small cell lung cancer epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2] Maria Fernanda Villarreal, M.D. [3]

Overview

Non-small cell lung cancer is the most common cancer worldwide and the leading cause of cancer-related mortality in the United States. Non-small cell lung cancer accounted for 1.8 million new cases and 1.6 million deaths of lung cancer in 2012. In the United States, the age-adjusted prevalence of non-small cell lung cancer is 47.2 per 100,000 individuals. The median age at diagnosis of non-small cell lung cancer is 70 years. Non-small cell lung cancer is most frequently diagnosed among people between 65 to 74 years old. Males are more commonly affected by non-small cell lung cancer than females. The male to female ratio is approximately 1.8 to 1. The rate of new cases in 2011 showed that males develop lung cancer more often than females (64.8 and 48.6 per 100,000 individuals). There is a racial preponderance to the development of non-small cell lung cancer, where African American individuals are at a significantly increased risk compared to Caucasian race.

Epidemiology and Demographics

Prevalence

  • In the United States, the age-adjusted prevalence of non-small cell lung cancer is 47.2 per 100,000 indivudals.[1]
  • About 85%–90% of all lung cancers are non-small cell lung cancer.[2]
  • The most common type of lung cancer is non-small cell lung cancer.[3][4]
    • Non-small cell lung cancer is the most common cancer worldwide, accounting for 1.8 million new cases and 1.6 million deaths in 2012.
    • Adenocarcinoma of the lung is the most common non-small cell lung cancer subtype in the United States.

Incidence

  • The age-adjusted incidence of non-small cell lung cancer in 2012 was estimated to be 58.7 per 100,000 individuals in the United States.[1]

Age

  • The incidence of non small cell lung cancer increases with age; the median age at diagnosis is 70 years.[5]
    • Non small cell lung cancer is most frequently diagnosed among people among 65 to 74 years old.
    • Shown below is an image that demonstrates the age-adjusted incidence of non-small cell lung cancer in the United States. These graphs are adapted from SEER: The Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.

Gender

  • Males are more commonly affected with non-small cell lung cancer than females. The male to female ratio is approximately 1.8 to 1.[5]
    • The rate of new cases in 2011 showed that males develop lung cancer more often than females (64.8 and 48.6 per 100,000 individuals).
    • Shown below is an image that demonstrates the relative proportions of common types of non-small cell lung cancer in the United States, by histology and gender. These graphs are adapted from SEER: The Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.

Race

  • There is a racial preponderance to the development of non small cell lung cancer, where African American individuals are at a significantly increased risk compared to Caucasian race.[4]
    • There is a higher prevalence of lung adenocarcinoma among Asian female patients with EGFR mutation (51.4%).
  • Shown below is an image that demonstrates the mortality rate of non-small cell lung cancer among different ethnic groups in the United States. These graphs are adapted from SEER: The Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.[5]

References

  1. 1.0 1.1 Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/statfacts/html/lungb.html, based on November 2013 SEER data submission, posted to the SEER web site. February 2016.
  2. Non small cell lung cancer. Canadian cancer society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/lung-cancer/non-small-cell-lung-cancer/?region=ab
  3. Molina JR, Yang P, Cassivi SD, Schild SE, Adjei AA (2008). "Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship". Mayo Clin. Proc. 83 (5): 584–94. doi:10.4065/83.5.584. PMC 2718421. PMID 18452692.
  4. 4.0 4.1 Tumors of the lung: epidemiology. WHO/IARC. 2006 https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb10/bb10-chap1.pdf Accessed on February 21, 2016
  5. 5.0 5.1 5.2 Subramanian J, Morgensztern D, Goodgame B, Baggstrom MQ, Gao F, Piccirillo J, Govindan R (2010). "Distinctive characteristics of non-small cell lung cancer (NSCLC) in the young: a surveillance, epidemiology, and end results (SEER) analysis". J Thorac Oncol. 5 (1): 23–8. doi:10.1097/JTO.0b013e3181c41e8d. PMID 19934774.


Template:WikiDoc Sources