Non-Hodgkin lymphoma risk factors: Difference between revisions

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{{CMG}}; {{AE}} {{AS}}
{{CMG}}; {{AE}} {{AS}}
==Overview==
==Overview==
The known risk factors in the development of Hodgkin's lymphoma are weakened immune system, [[autoimmune disorders]], certain infections and previous cancer treatment. Other possible risk factors include family history of Non-Hodgkin lymphoma, exposure to [[pesticides]], exposure to [[trichloroethylene]], [[diet]], [[obesity]], hair dyes, and occupational exposures.
The known risk factors in the development of Non-Hodgkin lymphoma are weakened immune system, [[autoimmune disorders]], certain infections and previous cancer treatment. Other possible risk factors include family history of Non-Hodgkin lymphoma, exposure to [[pesticides]], exposure to [[trichloroethylene]], [[diet]], [[obesity]], hair dyes, and occupational exposures.
==Risk Factors==
==Risk Factors==
The known risk factors in the development of Hodgkin's lymphoma are weakened immune system, [[autoimmune disorders]], certain infections and previous cancer treatment. Other possible risk factors include family history of Non-Hodgkin lymphoma, exposure to [[pesticides]], exposure to [[trichloroethylene]], [[diet]], [[obesity]], hair dyes, and occupational exposures.<ref name=CCS>{{cite web | title = Canadian Cancer Society Risk factors for non-Hodgkin lymphoma| url =http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/risks/?region=ab}}</ref>
The known risk factors in the development of Non-Hodgkin lymphoma are weakened immune system, [[autoimmune disorders]], certain infections and previous cancer treatment. Other possible risk factors include family history of Non-Hodgkin lymphoma, exposure to [[pesticides]], exposure to [[trichloroethylene]], [[diet]], [[obesity]], hair dyes, and occupational exposures.<ref name=CCS>{{cite web | title = Canadian Cancer Society Risk factors for non-Hodgkin lymphoma| url =http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/risks/?region=ab}}</ref>


{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
|+ '''Risk factors for Non-hodgkin lymphoma'''
|+ '''Risk factors for Non-Hodgkin lymphoma'''
! style="background: #4479BA; color:#FFF;" | Known risk factors
! style="background: #4479BA; color:#FFF;" | Known risk factors
! style="background: #4479BA; color:#FFF;" | Possible risk factors
! style="background: #4479BA; color:#FFF;" | Possible risk factors
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::* Linked with [[primary effusion lymphoma]], [[body cavity lymphoma]] and [[AIDS-related lymphoma]]
::* Linked with [[primary effusion lymphoma]], [[body cavity lymphoma]] and [[AIDS-related lymphoma]]
:* [[Hepatitis C virus]] (HCV) and [[hepatitis B virus]] (HBV)  
:* [[Hepatitis C virus]] (HCV) and [[hepatitis B virus]] (HBV)  
::* Higher risk of developing some types of Non-hodgkins lymphoma
::* Higher risk of developing some types of Non-Hodgkin lymphoma
* [[Bacterial]] infection  
* [[Bacterial]] infection  
:* [[Helicobacter pylori]] (H. pylori)  
:* [[Helicobacter pylori]] (H. pylori)  

Revision as of 13:16, 28 September 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

The known risk factors in the development of Non-Hodgkin lymphoma are weakened immune system, autoimmune disorders, certain infections and previous cancer treatment. Other possible risk factors include family history of Non-Hodgkin lymphoma, exposure to pesticides, exposure to trichloroethylene, diet, obesity, hair dyes, and occupational exposures.

Risk Factors

The known risk factors in the development of Non-Hodgkin lymphoma are weakened immune system, autoimmune disorders, certain infections and previous cancer treatment. Other possible risk factors include family history of Non-Hodgkin lymphoma, exposure to pesticides, exposure to trichloroethylene, diet, obesity, hair dyes, and occupational exposures.[1]

Risk factors for Non-Hodgkin lymphoma
Known risk factors Possible risk factors
Weakened immune system Family history of Non-Hodgkin lymphoma
Autoimmune disorders Exposure to pesticides
Certain infections Exposure to trichloroethylene
Previous cancer treatment Diet
Obesity
Hair dyes
Occupational exposures

A. Known risk factors

  • The likelihood of getting non-Hodgkin's lymphoma increases with age and is more common in men than in women.

1. Weakened immune system

  • a. Congenital immune system damage
  • Inherited immunodeficiency disorders are very rare, but acquired ones are a little more common
  • Inherited disorders
  • b. Acquired immune system damage
  • Acquired disorders
  • Immunosuppressant drugs for

2. Autoimmune disorders

  • Linked with diffuse large B-cell lymphoma
  • Hashimotos thyroiditis
  • Linked with a higher risk of developing primary thyroid lymphoma

3. Certain infections

  • Human T-cell leukemia/lymphoma virus, type 1 (HTLV-1)
  • Higher risk of developing some types of Non-Hodgkin lymphoma
  • Linked with a mucosa-associated lymphoid-tissue lymphoma (MALT lymphoma)

4. Previous cancer treatment

  • People who have received chemotherapy, with or without radiation therapy
  • People who have been treated for cancer have a higher risk of developing Non-hodgkin lymphoma for the rest of their lives
  • The risk of developing Non-hodgkin lymphoma is greatest in the first 5 years after treatment

B. Possible risk factors

  • 1. Family history of Non-hodgkin lymphoma
  • Non-hodgkin lymphoma is not generally considered to be familial, which means occurring in families more often than would be expected by chance
  • Higher risk of Non-hodgkin lymphoma in people with a first-degree relative (a parent, brother, sister or child) who has been diagnosed with lymphoma
  • Exposure to certain pesticides, such as Agent Orange, may be linked with a higher risk of developing Non-hodgkin lymphoma
  • Trichloroethylene (TCE) is a solvent used mostly to remove grease from metal
  • Exposure to TCE may increase the risk of developing Non-hodgkin lymphoma
  • 4. Diet
  • The link between Non-hodgkin lymphoma and diet is very complex
  • Diets high in meat, dairy products and saturated fat may increase the risk of developing Non-hodgkin lymphoma
  • Diets low in vegetables increase the risk of Non-hodgkin lymphoma
  • 5. Obesity
  • 6. Hair dyes
  • Higher risk in people who used hair dye before 1980
  • Risk affects people who used permanent dyes with dark colors in particular
  • Risk may also be higher in hair dressers and barbers, who were exposed to the dye at work
  • 7. Occupational exposures
  • Farming
  • Rubber industry
  • Wood and forestry
  • Printing
  • Welding

References

  1. "Canadian Cancer Society Risk factors for non-Hodgkin lymphoma".

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