Neurosyphilis historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

In 1836, Marshall Hall an English physician found a patient with loss of postural control in darkness caused by severely compromised proprioception, but He did not develop more information about it. In 1840, Moritz Heinrich Romberg, a german physician was the first who discovered tabes dorsalis which is the most prominent manifestation of neurosyphilis. He described excessive drinking and increase sexual activity may be the causes of tabes dorsalis. He named the disease as progressive locomotor ataxia. He was unable to find the relation between syphilis and tabes doesalis. In 1858, Guillaume Duchenne a French neurologist for the first time described the association between syphilis and neurosyphilis .In 1875, Jean-Alfred Fournier, a French dermatologist conclusively described the syphilis as the main cause of tabes dorsalis. In 1888, Sir William R. Gowers a British neurologist gave accurate details of the modern Romberg's test.

Historical Perspective

The main points in historical Perspective of neurosyphilis are:[1][2][3][4]

  • In 1836, Marshall Hall, an English physician, found a patient with loss of postural control in darkness caused by severely compromised proprioception. but He did not develop more information about it.

References

  1. Vora SK, Lyons RW (2004). "The medical Kipling--syphilis, tabes dorsalis, and Romberg's test". Emerg Infect Dis. 10 (6): 1160–2. doi:10.3201/eid1006.031117. PMC 3323152. PMID 15224672.
  2. Lanska DJ (2002). "The Romberg sign and early instruments for measuring postural sway". Semin Neurol. 22 (4): 409–18. doi:10.1055/s-2002-36763. PMID 12539062.
  3. Housman B, Bellary SS, Walters A, Mirzayan N, Tubbs RS, Loukas M (2014). "Moritz Heinrich Romberg (1795-1873): Early founder of neurology". Clin Anat. 27 (2): 147–9. doi:10.1002/ca.22112. PMID 22711686.
  4. Betekhin MS (2012). "[Jean Alfred Fournier: to 180th anniversary]". Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med (6): 57–9. PMID 23634617.

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