Neurosyphilis MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

Spinal and brain MRI may be helpful in the diagnosis of tabes dorsalis. Findings on MRI suggestive of tabes dorsalis include longitudinal T2-weighted hyperintensity in the dorsal columns of the spinal cord, narrowing between the cervical intervertebral discs and partial ankylosis of the cervical disc space, bilateral high intensity signals on the T2 weighted sequence located in mesiotemporal, insular, frontal regions, calcification of the ligamentum flavum.

MRI

Spinal and brain MRI may be helpful in the diagnosis of tabes dorsalis. Findings on MRI suggestive of tabes dorsalis include:

References

  1. Bou-Haidar P, Peduto AJ, Karunaratne N (2009). "Differential diagnosis of T2 hyperintense spinal cord lesions: part B." J Med Imaging Radiat Oncol. 53 (2): 152–9. doi:10.1111/j.1754-9485.2009.02067.x. PMID 19527360.
  2. Sen A, Chandrasekhar K (2013). "Spinal MR imaging in Vitamin B12 deficiency: Case series; differential diagnosis of symmetrical posterior spinal cord lesions". Ann Indian Acad Neurol. 16 (2): 255–8. doi:10.4103/0972-2327.112487. PMC 3724087. PMID 23956577.
  3. 3.0 3.1 Salem KM, Majeed H, Bommireddy R, Klezl Z (2013). "Tertiary syphilis in the cervical spine: a case report and review of the literature". Global Spine J. 3 (1): 41–6. doi:10.1055/s-0032-1329887. PMC 3854603. PMID 24436850.
  4. Brisset M, Chadenat ML, Cordoliani Y, Kamga-Tallom R, D'Anglejean J, Pico F (2011). "[MRI features of neurosyphilis]". Rev Neurol (Paris). 167 (4): 337–42. doi:10.1016/j.neurol.2010.08.012. PMID 21440277.

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