NLK

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Nemo-like kinase
Identifiers
Symbols NLK ; DKFZp761G1211; FLJ21033
External IDs Template:OMIM5 HomoloGene88836
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Nemo-like kinase, also known as NLK, is a human gene.[1]


References

  1. "Entrez Gene: NLK nemo-like kinase".

Further reading

  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548.
  • Brott BK, Pinsky BA, Erikson RL (1998). "Nlk is a murine protein kinase related to Erk/MAP kinases and localized in the nucleus". Proc. Natl. Acad. Sci. U.S.A. 95 (3): 963–8. PMID 9448268.
  • Volorio S, Simon G, Repetto M; et al. (1999). "Sequencing analysis of forty-eight human image cDNA clones similar to Drosophila mutant protein". DNA Seq. 9 (5–6): 307–15. PMID 10524757.
  • Kehrer-Sawatzki H, Moschgath E, Maier C; et al. (2000). "Characterization of the Fugu rubripes NLK and FN5 genes flanking the NF1 (Neurofibromatosis type 1) gene in the 5' direction and mapping of the human counterparts". Gene. 251 (1): 63–71. PMID 10863097.
  • Kortenjann M, Wehrle C, Nehls MC, Boehm T (2002). "Only one nemo-like kinase gene homologue in invertebrate and mammalian genomes". Gene. 278 (1–2): 161–5. PMID 11707333.
  • Wistow G, Bernstein SL, Wyatt MK; et al. (2002). "Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts". Mol. Vis. 8: 196–204. PMID 12107411.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Ishitani T, Kishida S, Hyodo-Miura J; et al. (2003). "The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling". Mol. Cell. Biol. 23 (1): 131–9. PMID 12482967.
  • Ishitani T, Ninomiya-Tsuji J, Matsumoto K (2003). "Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling". Mol. Cell. Biol. 23 (4): 1379–89. PMID 12556497.
  • Yasuda J, Tsuchiya A, Yamada T; et al. (2003). "Nemo-like kinase induces apoptosis in DLD-1 human colon cancer cells". Biochem. Biophys. Res. Commun. 308 (2): 227–33. PMID 12901858.
  • Yasuda J, Yokoo H, Yamada T; et al. (2004). "Nemo-like kinase suppresses a wide range of transcription factors, including nuclear factor-kappaB". Cancer Sci. 95 (1): 52–7. PMID 14720327.
  • Smit L, Baas A, Kuipers J; et al. (2004). "Wnt activates the Tak1/Nemo-like kinase pathway". J. Biol. Chem. 279 (17): 17232–40. doi:10.1074/jbc.M307801200. PMID 14960582.
  • Kanei-Ishii C, Ninomiya-Tsuji J, Tanikawa J; et al. (2004). "Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK". Genes Dev. 18 (7): 816–29. doi:10.1101/gad.1170604. PMID 15082531.
  • Kanei-Ishii C, Nomura T, Tanikawa J; et al. (2004). "Differential sensitivity of v-Myb and c-Myb to Wnt-1-induced protein degradation". J. Biol. Chem. 279 (43): 44582–9. doi:10.1074/jbc.M407831200. PMID 15308626.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Kojima H, Sasaki T, Ishitani T; et al. (2005). "STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation". Proc. Natl. Acad. Sci. U.S.A. 102 (12): 4524–9. doi:10.1073/pnas.0500679102. PMID 15764709.
  • Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
  • Lim J, Hao T, Shaw C; et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
  • Gohda J, Irisawa M, Tanaka Y; et al. (2007). "HTLV-1 Tax-induced NFkappaB activation is independent of Lys-63-linked-type polyubiquitination". Biochem. Biophys. Res. Commun. 357 (1): 225–30. doi:10.1016/j.bbrc.2007.03.125. PMID 17418100.

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