NDST1

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N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
File:PBB Protein NDST1 image.jpg
PDB rendering based on 1nst.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols NDST1 ; HSST; NST1
External IDs Template:OMIM5 Template:MGI HomoloGene20386
RNA expression pattern
File:PBB GE NDST1 202608 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1, also known as NDST1, is a human gene.[1]


References

  1. "Entrez Gene: NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1".

Further reading

  • Dixon J, Loftus SK, Gladwin AJ; et al. (1995). "Cloning of the human heparan sulfate-N-deacetylase/N-sulfotransferase gene from the Treacher Collins syndrome candidate region at 5q32-q33.1". Genomics. 26 (2): 239–44. PMID 7601448.
  • Humphries DE, Sullivan BM, Aleixo MD, Stow JL (1997). "Localization of human heparan glucosaminyl N-deacetylase/N-sulphotransferase to the trans-Golgi network". Biochem. J. 325 ( Pt 2): 351–7. PMID 9230113.
  • Sueyoshi T, Kakuta Y, Pedersen LC; et al. (1998). "A role of Lys614 in the sulfotransferase activity of human heparan sulfate N-deacetylase/N-sulfotransferase". FEBS Lett. 433 (3): 211–4. PMID 9744796.
  • Aikawa J, Esko JD (1999). "Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family". J. Biol. Chem. 274 (5): 2690–5. PMID 9915799.
  • Kakuta Y, Sueyoshi T, Negishi M, Pedersen LC (1999). "Crystal structure of the sulfotransferase domain of human heparan sulfate N-deacetylase/ N-sulfotransferase 1". J. Biol. Chem. 274 (16): 10673–6. PMID 10196134.
  • Pikas DS, Eriksson I, Kjellén L (2000). "Overexpression of different isoforms of glucosaminyl N-deacetylase/N-sulfotransferase results in distinct heparan sulfate N-sulfation patterns". Biochemistry. 39 (15): 4552–8. PMID 10758005.
  • Mura CV, Becker MI, Orellana A, Wolff D (2002). "Immunopurification of Golgi vesicles by magnetic sorting". J. Immunol. Methods. 260 (1–2): 263–71. PMID 11792394.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Bengtsson J, Eriksson I, Kjellén L (2003). "Distinct effects on heparan sulfate structure by different active site mutations in NDST-1". Biochemistry. 42 (7): 2110–5. doi:10.1021/bi026928g. PMID 12590599.
  • van den Born J, Pikas DS, Pisa BJ; et al. (2003). "Antibody-based assay for N-deacetylase activity of heparan sulfate/heparin N-deacetylase/N-sulfotransferase (NDST): novel characteristics of NDST-1 and -2". Glycobiology. 13 (1): 1–10. doi:10.1093/glycob/cwg011. PMID 12634318.
  • Nakayama K, Natori Y, Sato T; et al. (2004). "Altered expression of NDST-1 messenger RNA in puromycin aminonucleoside nephrosis". J. Lab. Clin. Med. 143 (2): 106–14. doi:10.1016/j.lab.2003.10.012. PMID 14966466.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.

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