NACA (gene)

Nascent-polypeptide-associated complex alpha polypeptide
Identifiers
Symbols	NACA ; HSD48; MGC117224
External IDs	Template:OMIM5 Template:MGI HomoloGene: 55914
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE NACA 200735 x at tn.png
File:PBB GE NACA 208635 x at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Nascent-polypeptide-associated complex alpha polypeptide, also known as NACA, is a human gene.

Further reading

• Wiedmann B, Sakai H, Davis TA, Wiedmann M (1994). "A protein complex required for signal-sequence-specific sorting and translocation". Nature. 370 (6489): 434–40. doi:10.1038/370434a0. PMID 8047162.CS1 maint: Multiple names: authors list (link)
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
• Yotov WV, St-Arnaud R (1996). "Mapping of the human gene for the alpha-NAC/1.9.2 (NACA/1.9.2) transcriptional coactivator to Chromosome 12q23-24.1". Mamm. Genome. 7 (2): 163–4. PMID 8835540.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yotov WV, Moreau A, St-Arnaud R (1998). "The alpha chain of the nascent polypeptide-associated complex functions as a transcriptional coactivator". Mol. Cell. Biol. 18 (3): 1303–11. PMID 9488445.CS1 maint: Multiple names: authors list (link)
• Moreau A, Yotov WV, Glorieux FH, St-Arnaud R (1998). "Bone-specific expression of the alpha chain of the nascent polypeptide-associated complex, a coactivator potentiating c-Jun-mediated transcription". Mol. Cell. Biol. 18 (3): 1312–21. PMID 9488446.CS1 maint: Multiple names: authors list (link)
• Munz B, Wiedmann M, Lochmüller H, Werner S (1999). "Cloning of novel injury-regulated genes. Implications for an important role of the muscle-specific protein skNAC in muscle repair". J. Biol. Chem. 274 (19): 13305–10. PMID 10224091.CS1 maint: Multiple names: authors list (link)
• Beatrix B, Sakai H, Wiedmann M (2001). "The alpha and beta subunit of the nascent polypeptide-associated complex have distinct functions". J. Biol. Chem. 275 (48): 37838–45. doi:10.1074/jbc.M006368200. PMID 10982809.CS1 maint: Multiple names: authors list (link)
• Zhang QH, Ye M, Wu XY; et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. PMID 11042152.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sims RJ, Weihe EK, Zhu L; et al. (2002). "m-Bop, a repressor protein essential for cardiogenesis, interacts with skNAC, a heart- and muscle-specific transcription factor". J. Biol. Chem. 277 (29): 26524–9. doi:10.1074/jbc.M204121200. PMID 12011100.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kim SH, Shim KS, Lubec G (2002). "Human brain nascent polypeptide-associated complex alpha subunit is decreased in patients with Alzheimer' s disease and Down syndrome". J. Investig. Med. 50 (4): 293–301. PMID 12109594.CS1 maint: Multiple names: authors list (link)
• Behrends U, Jandl T, Golbeck A; et al. (2002). "Novel products of the HUD, HUC, NNP-1 and alpha-internexin genes identified by autologous antibody screening of a pediatric neuroblastoma library". Int. J. Cancer. 100 (6): 669–77. doi:10.1002/ijc.10550. PMID 12209604.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mossabeb R, Seiberler S, Mittermann I; et al. (2002). "Characterization of a novel isoform of alpha-nascent polypeptide-associated complex as IgE-defined autoantigen". J. Invest. Dermatol. 119 (4): 820–9. doi:10.1046/j.1523-1747.2002.00518.x. PMID 12406326.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Stilo R, Liguoro D, di Jeso B; et al. (2003). "The alpha-chain of the nascent polypeptide-associated complex binds to and regulates FADD function". Biochem. Biophys. Res. Commun. 303 (4): 1034–41. PMID 12684039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Papachristou DJ, Batistatou A, Sykiotis GP; et al. (2003). "Activation of the JNK-AP-1 signal transduction pathway is associated with pathogenesis and progression of human osteosarcomas". Bone. 32 (4): 364–71. PMID 12689679.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hämmerle K, Shayan P, Niemeyer CM, Flotho C (2003). "Expression analysis of alpha-NAC and ANX2 in juvenile myelomonocytic leukemia using SMART polymerase chain reaction and "virtual Northern" hybridization". Cancer Genet. Cytogenet. 142 (2): 149–52. PMID 12699894.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Al-Shanti N, Steward CG, Garland RJ, Rowbottom AW (2004). "Investigation of alpha nascent polypeptide-associated complex functions in a human CD8(+) T cell ex vivo expansion model using antisense oligonucleotides". Immunology. 112 (3): 397–403. doi:10.1111/j.1365-2567.2004.01893.x. PMID 15196207.CS1 maint: Multiple names: authors list (link)
• Ballif BA, Villén J, Beausoleil SA; et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)