Myelodysplastic syndrome

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Myelodysplastic syndrome
ICD-10 D46
ICD-9 238.7
ICD-O: 9980/0-9989/3
DiseasesDB 8604
MeSH D009190

Myelodysplastic syndrome Microchapters

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Overview

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Pathophysiology

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Differentiating Myelodysplastic syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

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Natural History, Complications and Prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

Classification

Pathophysiology

Epidemiology & Demographics

Risk Factors

Screening

Causes

Differentiating Myelodysplastic syndrome from other Diseases

Natural History, Complications & Prognosis

Diagnosis

History & Symptoms | Physical Examination | Staging | Lab Tests | Electrocardiogram | Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention

Related chapters

Additional Readings

  • Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR, Sultan C. Proposals for the classification of the myelodysplastic syndromes. Br J Haematol 1982;51:189. PMID 6952920.
  • Block M, Jacobson LO, Bethard WF. Preleukemic acute human leukemia. JAMA 1953;152:1018-28. PMID 13052490.
  • Harris NL, Jaffe ES, Diebold J, Flandrin G, Muller-Hermelink HK, Vardiman J, Lister TA, Bloomfield CD. World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting-Airlie House, Virginia, November 1997. J Clin Oncol 1999;17:3835-49. PMID 10577857.
  • Foucar, K Bone Marrow Pathology, 2nd Edition, ASCP Press. c 2001
  • Greenberg, Peter L. (editor) "Myelodysplastic Syndromes: Clinical and Biological Advances" Cambridge University Press, New York 2006 ISBN 978-0521496681 ISBN 0521496683
  • Steensma DP, Gibbons RJ, Higgs DR. "Acquired alpha-thalassemia in association with myelodysplastic syndrome and other hematologic malignancies." Blood 2005;105:443-452. PMID 15358626.
  • List A, Dewald G, Bennett J, Giagnounidis A, Raza A, Feldman E, Powell B, Greenberg P, Thomas D, Store R, Reeder C, Wride K, Patin J, Schmidt M, Zeldis J, Knight R. "Lenalidomide in the Myelodysplastic Syndrome with Chromosome 5q Deletion." NEJM 2006;355(14):1456-1465. PMID 17021321.
  • Fenaux P, Mufti GJ, Lindberg EH, Santini V, Finelli C, Giagounidis A, Schoch R, Gatterman N, Sanz G, List A, Gore SD, Seymour JF, Bennett JM, Byrd J, Backstrum J, Zimmerman JF, McKenzie D, Beach CL, Silverman LR. "Efficacy of Azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised open-label phase III study." Lancet Oncology 2009;10(3):223-232. PMID 19230772.

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