Mycobacterium avium complex infection: Difference between revisions
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== Pathophysiology & Etiology== | == Pathophysiology & Etiology== | ||
Revision as of 14:01, 1 October 2012
| Mycobacterium avium complex infection |
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Mycobacterium avium complex infection Microchapters |
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Differentiating Mycobacterium avium complex infection from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Mycobacterium avium complex infection On the Web |
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American Roentgen Ray Society Images of Mycobacterium avium complex infection |
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Directions to Hospitals Treating Mycobacterium avium complex infection |
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Risk calculators and risk factors for Mycobacterium avium complex infection |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Related Key Words and Synonyms:
Pathophysiology & Etiology
Etiologic Agent:
Mycobacterium avium complex (comprising M. avium and M.intracellulare).
Transmission:
Although the mode of transmission is unclear, MAC is most likely environmentally acquired.
Diagnosis
Diagnosis can be achieved through blood cultures, or cultures of other bodily fluids such as lymphatic dranage or stool. Bone marrow culture can often yield an earlier diagnosis, but is usually avoided as an initial diagnostic step because of its invasiveness.
History and Symptoms
Several different syndromes are caused by Mycobacterium avium complex (MAC). Disseminated infections are usually associated with HIV infection. Less commonly, pulmonary disease in nonimmunocompromised persons is a result of infection with MAC. In children, the most common syndrome is cervical lymphadenitis.
In HIV infected persons, manifestations include night sweats, weight loss, abdominal pain, fatigue, diarrhea, and anemia.
Risk Stratification and Prognosis
Incidence is decreasing because of changes in treatment for HIV-infected patients; however, antimicrobial resistance may be increasing.
Treatment
Pharmacotherapy
Treatment involves a combination of anti-tuberculosis antibiotics. These include:
References
- http://www.cdc.gov/ncidod/dbmd/diseaseinfo/mycobacteriumavium_t.htm
- http://en.wikipedia.org/wiki/Mycobacterium_avium_complex
Acknowledgements
The content on this page was first contributed by: C. Michael Gibson, M.S., M.D. Template:SIB