Mirtazapine

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Synonyms / Brand Names: Mirtazapina, Mirtazapinum, Mirtazepine, Mepirzepine, Remeron, Remeron Soltab, Zispin, Remergil, Norset, Rexer, Remergon, Mirtabene, Avanza, Mirtazon, Axit, Mirtaz, Promyrtil

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Dosing and Administration

The recommended starting dose for Mirtazapine tablets USP is 15 mg/day, administered in a single dose, preferably in the evening prior to sleep. In the controlled clinical trials establishing the efficacy of Mirtazapine in the treatment of major depressive disorder, the effective dose range was generally 15 mg/day to 45 mg/day. While the relationship between dose and satisfactory response in the treatment of major depressive disorder for Mirtazapine has not been adequately explored, patients not responding to the initial 15 mg dose may benefit from dose increases up to a maximum of 45 mg/day. Mirtazapine has an elimination half-life of approximately 20 to 40 hours, therefore, dose changes should not be made at intervals of less than one to two weeks in order to allow sufficient time for evaluation of the therapeutic response to a given dose.



FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.

Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.

Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.

Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information

Trial Resources
Ongoing Trials, Trial Results

Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.

Media Resources
Slides, Video, Images, MP3, Podcasts, etc.

Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.

International Resources
en Español






FDA Package Insert Resources

Indications

Contraindications

Side Effects

Drug Interactions

Precautions

Overdose

Instructions for Administration

How Supplied

Pharmacokinetics and Molecular Data

FDA label

FDA on Mirtazapine

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Publication Resources

Most Recent Articles on Mirtazapine

Review Articles on Mirtazapine

Articles on Mirtazapine in N Eng J Med, Lancet, BMJ

WikiDoc State of the Art Review

Textbook Information on Mirtazapine

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Trial Resources

Ongoing Trials with Mirtazapine at Clinical Trials.gov

Trial Results with Mirtazapine

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Guidelines & Evidence Based Medicine Resources

US National Guidelines Clearinghouse on Mirtazapine

Cochrane Collaboration on Mirtazapine

Cost Effectiveness of Mirtazapine

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Media Resources

Powerpoint Slides on Mirtazapine

Images of Mirtazapine

Podcasts & MP3s on Mirtazapine

Videos on Mirtazapine

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Patient Resources

Patient Information from National Library of Medicine

Patient Resources on Mirtazapine

Discussion Groups on Mirtazapine

Patient Handouts on Mirtazapine

Blogs on Mirtazapine

Mirtazapine in the News

Mirtazapine in the Marketplace

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International Resources

Mirtazapine en Español

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Adapted from the FDA Package Insert.